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Grantee Research Project Results

Journal Publications Details for Grant Number R840033

An in vitro-in silico hybrid approach for high-throughput estimation of trans-barrier permeability for chemical pollutants

RFA: Advancing Toxicokinetics for Efficient and Robust Chemical Evaluations (2019)

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Journal Article (9)
Reference Type Reference Title Journal Author Citation Progress Report Year Document Sources
Journal Article Comparison of in vitro membrane permeabilities of diverse environmental chemicals with in silico predictions SCIENCE OF THE TOTAL ENVIRONMENT Intasiri A, Illa S, Prertprawnon S, Wang S, Bell T, Li L, Li D Intasiri A, Illa S, Prertprawnon S, Wang S, Bell T, Li L, Li D. Comparison of in vitro membrane permeabilities of diverse environmental chemicals with in silico predictions. SCIENCE OF THE TOTAL ENVIRONMENT 2024;933 R840033 (2023)
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Journal Article Human Chemical Exposure from Background Emissions in the United States and the Implication for Quantifying Risks from Marginal Emission Increase. TOXICS Li D, Li L Li D, Li L. Human chemical exposure from background emissions in the United States and the implication for quantifying risks from marginal emission increase. Toxics 2021;9(11):308. R840033 (2022)
R840033 (Final)
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Journal Article Understanding the Impacts of Presystemic Metabolism on the Human Oral Bioavailability of Chemicals ENVIRONMENTAL SCIENCE & TECHNOLOGY Wang S, Zhang Z, Saunders L, Li D, Li L Wang S, Zhang Z, Saunders L, Li D, Li L. Understanding the Impacts of Presystemic Metabolism on the Human Oral Bioavailability of Chemicals. ENVIRONMENTAL SCIENCE & TECHNOLOGY 2024; R840033 (2023)
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Journal Article Elucidating impacts of partitioning and transmembrane permeability on absorption of chemicals in human gastrointestinal tract ENVIRONMENT INTERNATIONAL Wang S, Zhang Z, Li D Wang S, Zhang Z, Li D. Elucidating impacts of partitioning and transmembrane permeability on absorption of chemicals in human gastrointestinal tract. Environment International 2024;193. R840033 (2023)
R840033 (Final)
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Journal Article Emerging investigator series: the role of chemical properties in human exposure to environmental chemicals. ENVIRONMENTAL SCIENCES: PROCESS IMPACTS Zhang Z, Wang S, Li L Zhang Z, Wang S, Li L. Emerging investigator series:the role of chemical properties in human exposure to environmental chemicals. Environmental Sciences: Process Impacts 2021;23(12):1839-1862. R840033 (2022)
R840033 (Final)
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Journal Article Evaluating consumer exposure to disinfecting chemicals against coronavirus disease 2019 (COVID-19) and associated health risks. ENVIRONMENT INTERNATIONAL Li D, Sangion A, Li L Li D, Sangion A, Li L. Evaluating consumer exposure to disinfecting chemicals against coronavirus disease 2019 (COVID-19) and associated health risks. Environment International 2020;145:106108. R840033 (Final)
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Journal Article In silico model-based exploration of the applicability of parallel artificial membrane permeability assay (PAMPA) to screen chemicals of environmental concern. ENVIRONMENT INTERNATIONAL Wang S, Zhang Z, Li D, Illa SE, Li L Wang S, Zhang Z, Li D, Illa SE, Li L. In silico model-based exploration of the applicability of parallel artificial membrane permeability assay (PAMPA) to screen chemicals of environmental concern. Environment International 2022;170:107589. R840033 (Final)
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Journal Article Comparison of in vitro membrane permeabilities of diverse environmental chemicals with in silico predictions. SCIENCE OF THE TOTAL ENVIRONMENT Intasiri A, Illa SE, Prertprawnon S, Wang S, Li L, Bell TW, Li D Intasiri A, Illa SE, Prertprawnon S, Wang S, Li L, Bell TW, Li D. Comparison of in vitro membrane permeabilities of diverse environmental chemicals with in silico predictions. Science of The Total Environment 2024;933:173244. R840033 (Final)
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Journal Article Understanding the impacts of presystemic metabolism on the human oral bioavailability of chemicals. ENVIRONMENTAL SCIENCE & TECHNOLOGY Wang S, Zhang Z, Saunders LJ, Li D, Li L Wang S, Zhang Z, Saunders LJ, Li D, Li L. Understanding the impacts of presystemic metabolism on the human oral bioavailability of chemicals. Environmental Science & Technology 2024;58(32):14135-14145. R840033 (Final)
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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