Grantee Research Project Results
Final Report: Determination of Aggregate and Cumulative Exposures of Perfluorinated Compounds Consistent with Biomarkers of the Compounds Using Simulation Modeling of Exposure and Pharmacokinetics
EPA Grant Number: R833450Title: Determination of Aggregate and Cumulative Exposures of Perfluorinated Compounds Consistent with Biomarkers of the Compounds Using Simulation Modeling of Exposure and Pharmacokinetics
Investigators: Chaisson, Christine , Franklin, Claire A. , Andersen, Melvin E. , Tedder, Douglas R. , Mathis, Eric T. , Krewski, Daniel , Clewell, Harvey , Jayjock, Michael , Ramsay, Tim , Tan, Yu-Mei
Institution: The LifeLine Group, Inc. , University of Ottawa’s Institute for Population Health , Center for Human Health Assessment CIIT Centers for Health Research
Current Institution: The LifeLine Group, Inc. , Center for Human Health Assessment CIIT Centers for Health Research , University of Ottawa’s Institute for Population Health
EPA Project Officer: Hahn, Intaek
Project Period: May 1, 2007 through May 1, 2010
Project Amount: $749,991
RFA: Interpretation of Biomarkers Using Physiologically Based Pharmacokinetic Modeling (2006) RFA Text | Recipients Lists
Research Category: Human Health
Journal Articles on this Report : 1 Displayed | Download in RIS Format
| Other project views: | All 1 publications | 1 publications in selected types | All 1 journal articles |
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Loccisano AE, Campbell Jr JL, Andersen ME, Clewell III HJ. Evaluation and prediction of pharmacokinetics of PFOA and PFOS in the monkey and human using a PBPK model. Regulatory Toxicology and Pharmacology 2011;59(1):157-175. |
R833450 (Final) |
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Supplemental Keywords:
Health, RFA, Scientific Discipline, Health Risk Assessment, Risk Assessments, Biology, Environmental Chemistry, Endocrine Disruptors - Human Health, endocrine disruptors, Biochemistry, Endocrine Disruptors - Environmental Exposure & Risk, toxicity, neurotoxic, dose response, bioindicator, human growth and development, developmental biology, exposure studies, ecological risk assessment model, hormone production, assessment technology, thyroid toxicants, human health riskProgress and Final Reports:
Original AbstractThe perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.