Grantee Research Project Results
2007 Progress Report: Carbon Nanotubes: Environmental Dispersion States, Transport, Fate, and Bioavailability
EPA Grant Number: R833321Title: Carbon Nanotubes: Environmental Dispersion States, Transport, Fate, and Bioavailability
Investigators: Weber, Walter J. , Huang, Qingguo
Institution: University of Michigan
EPA Project Officer: Hahn, Intaek
Project Period: March 1, 2007 through March 1, 2010
Project Period Covered by this Report: September 1, 2006 through August 31,2007
Project Amount: $371,886
RFA: Exploratory Research: Nanotechnology Research Grants Investigating Environmental and Human Health Effects of Manufactured Nanomaterials: a Joint Research Solicitation-EPA, NSF, NIOSH, NIEHS (2006) RFA Text | Recipients Lists
Research Category: Hazardous Waste/Remediation , Nanotechnology , Safer Chemicals
Objective:
Our overarching goal is to evaluate factors that control the environmental dispersion states, transport, fate, and bioavailability of carbon nanotubes, thereby providing a foundation for human and ecological risk assessment. Specifically, single-walled and multi-walled 14C-labeled carbon nanotubes will be synthesized, purified, and characterized using techniques previously established in our lab. These radio-labeled materials will then be used to systematically investigate i) the dispersion states of these nanomaterials under typical environmental conditions, ii) their transport behaviors within and through a series of different types of soil and sediment media, and iii) their bioavailability to selected critical aquatic and terrestrial food-chain organisms.
Approach:
We have developed and refined a means for producing single-walled and multi-walled 14C-labeled carbon nanotubes by using radioactively labeled methane as a feedstock for the synthesis of carbon nanotubes via chemical vapor deposition methods. Carbon nanotubes will be mixed with natural organic matter and subjected to a wide range of aquatic conditions (i.e., pH, ionic strength, etc.) to elucidate their dispersion state in natural environments. Carbon nanotube transport through a series of soil and sediment sorbent materials having different geochemical properties will be tested in dynamic column studies, and relationships among the breakthrough behaviors and the properties of both the nanotubes and the geosorbent materials will be analyzed. Carbon nanotube bioavailability to a fish, an aquatic worm, and an earthworm will be tested in lab-scale systems to examine the potentials of these nanomaterials to enter food chains in different environments, and factors controlling ecological bioavailability will be determined.
Progress Summary:
Expected Results:
The proposed study will provide: a) fundamental information regarding carbon nanotube dispersion states, transport, fate, and bioavailability in different environmental systems; b) identify factors controlling these environmental behaviors; and c) establish deterministic models capable of predicting behaviors under different environmental conditions. This information is critically needed by EPA and the research community for rigorous assessments of the environmental fate, transport, and ecological risks of carbon nanotubes in various soil/water/sediment systems.
Journal Articles on this Report : 10 Displayed | Download in RIS Format
Other project views: | All 14 publications | 10 publications in selected types | All 10 journal articles |
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Liu X, O'Carroll DM, Petersen EJ, Huang Q, Anderson CL. Mobility of multiwalled carbon nanotubes in porous media. Environmental Science & Technology 2009;43(21):8153-8158. |
R833321 (2007) R834094 (Final) |
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Petersen EJ, Huang Q, Weber Jr WJ. Bioaccumulation of radio-labeled carbon nanotubes by Eisenia foetida. Environmental Science & Technology 2008;42(8):3090-3095. |
R833321 (2007) |
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Petersen EJ, Huang Q, Weber WJ Jr. Ecological uptake and depuration of carbon nanotubes by Lumbriculus variegatus. Environmental Health Perspectives 2008;116(4):496-500. |
R833321 (2007) |
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Petersen EJ, Akkanen J, Kukkonen JVK, Weber Jr WJ. Biological uptake and depuration of carbon nanotubes by Daphnia magna. Environmental Science & Technology 2009;43(8):2969-2975. |
R833321 (2007) |
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Petersen EJ, Pinto RA, Landrum PF, Weber Jr WJ. Influence of carbon nanotubes on pyrene bioaccumulation from contaminated soils by earthworms. Environmental Science & Technology 2009;43(11):4181-4187. |
R833321 (2007) |
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Petersen EJ, Huang Q, Weber Jr. WJ. Relevance of octanol-water distribution measurements to the potential ecological uptake of multi-walled carbon nanotubes. Environmental Toxicology and Chemistry 2010;29(5):1106-1112. |
R833321 (2007) R834094 (Final) |
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Petersen EJ, Pinto RA, Zhang L, Huang Q, Landrum PF, Weber Jr. WJ. Effects of polyethyleneimine-mediated functionalization of multi-walled carbon nanotubes on earthworm bioaccumulation and sorption by soils. Environmental Science & Technology 2011;45(8):3718-3724. |
R833321 (2007) R834094 (Final) |
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Petersen EJ, Pinto RA, Mai DJ, Landrum PF, Weber Jr WJ. Influence of polyethyleneimine graftings of multi-walled carbon nanotubes on their accumulation and elimination by and toxicity to Daphnia magna. Environmental Science & Technology 2011;45(3):1133-1138. |
R833321 (2007) |
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Shi X, Wang SH, Shen M, Antwerp ME, Chen X, Li C, Petersen EJ, Huang Q, Weber Jr WJ, Baker Jr JR. Multifunctional dendrimer-modified multiwalled carbon nanotubes: synthesis, characterization, and in vitro cancer cell targeting and imaging. Biomacromolecules 2009;10(7):1744-1750. |
R833321 (2007) R834094 (Final) |
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Tervonen K, Waissi G, Petersen EJ, Akkanen J, Kukkonen JVK. Analysis of fullerene-C60 and kinetic measurements for its accumulation and depuration in Daphnia magna. Environmental Toxicology and Chemistry 2010;29(5):1072-1078. |
R833321 (2007) |
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Supplemental Keywords:
, Health, Scientific Discipline, PHYSICAL ASPECTS, Health Risk Assessment, Risk Assessments, Biochemistry, Physical Processes, biological pathways, bioavailability, exposure, nanotechnology, carbon fullerene, human exposure, nanomaterials, toxicologic assessment, nanoparticle toxicity, carcinogenicProgress and Final Reports:
Original AbstractThe perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.