Grantee Research Project Results
Final Report: Impacts of Manufactured Nanomaterials on Human Health and the Environment - A Focus on Nanoparticulate Aerosol and Atmospherically Processed Nanoparticulate Aerosol
EPA Grant Number: R831717Title: Impacts of Manufactured Nanomaterials on Human Health and the Environment - A Focus on Nanoparticulate Aerosol and Atmospherically Processed Nanoparticulate Aerosol
Investigators: Grassian, Vicki H. , Thorne, Peter S. , O'Shaughnessy, Patrick
Institution: University of Iowa
EPA Project Officer: Aja, Hayley
Project Period: October 1, 2004 through September 30, 2007
Project Amount: $335,000
RFA: Exploratory Research to Anticipate Future Environmental Issues: Impacts of Manufactured Nanomaterials on Human Health and the Environment (2003) RFA Text | Recipients Lists
Research Category: Nanotechnology , Safer Chemicals , Human Health
Objective:
In this research, the potential effects of manufactured nanoparticle aerosol on human health were investigated. This research was conducted to satisfy three main objectives. These objectives are to:
- characterize fully a variety of manufactured nanomaterials in terms of their size, shape, bulk and surface properties;
- determine if engineered nanomaterials are particularly deleterious to health compared to particles from combustion processes that have been more extensively studied; and
- evaluate the relative health effects caused by different surface coatings on the nanoparticle.
To carry out these objectives a variety of different chemical classes of nanomaterials were investigated. Surface coatings, or capping groups, often are used to control particle size in manufacturing so we investigated the effects of surface coatings from the manufacturing process in the toxicity of manufactured nanomaterials. We have focused our attention on metal and metal oxide based nanomaterials as these materials have wide ranging applications and are being used in consumer products.
Summary/Accomplishments (Outputs/Outcomes):
Journal Articles on this Report : 1 Displayed | Download in RIS Format
Other project views: | All 21 publications | 6 publications in selected types | All 5 journal articles |
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Type | Citation | ||
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Grassian V. When Size Really Matters: Size-Dependent Properties and Surface Chemistry of Metal and Metal Oxide Nanoparticles in Gas and Liquid Phase Environments. JOURNAL OF PHYSICAL CHEMISTRY 2008;112(47):18303-18313 |
R831717 (Final) |
Exit |
Supplemental Keywords:
ambient air, risk assessment, health effects, human health, particulates, environmental chemistry, industry, scientific discipline, health, physical aspects, risk assessments, health risk assessment, physical processes, biochemistry, environmental chemistry, biochemical research, nanotechnology, respiratory impact, inhalation study, engineered nanomaterials, inhalation toxicology, carbon fullerene, cytokines, human health risk, particle exposure, ambient particle health effects, particulate matter, exposure, human exposure, Health, PHYSICAL ASPECTS, Scientific Discipline, Environmental Chemistry, Health Risk Assessment, Risk Assessments, Physical Processes, Biochemistry, particulate matter, particle size, cytokines, carbon fullerene, exposure, nanotechnology, particle exposure, ambient particle health effects, human exposure, engineered nanomaterials, respiratory impact, inhalation toxicology, inhalation study, biochemical researchProgress and Final Reports:
Original AbstractThe perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.