Grantee Research Project Results
2024 Progress Report: Development of a Wastewater Hierarchical Sentinel Site Identification for Future Pandemic Surveillance Systems
EPA Grant Number: R840487Title: Development of a Wastewater Hierarchical Sentinel Site Identification for Future Pandemic Surveillance Systems
Investigators: Nguyen, Thanh (Helen) H. , Jutla, Antarpreet , Smith, Rebecca , Schmidt, Arthur , Keefer, Laura , Unnikrishnan, Avinash , Galan, Deise
Institution: University of Illinois Urbana-Champaign , Portland State University , University of Florida , National Association of County and City Health Officials
EPA Project Officer: Callan, Richard
Project Period: September 1, 2022 through April 29, 2025
Project Period Covered by this Report: September 1, 2023 through August 31,2024
Project Amount: $1,000,000
RFA: National Priorities: Innovative Sampling Designs for Public Health Surveillance of Coronaviruses and Other Pathogens in Wastewater Request for Applications (RFA) (2022) RFA Text | Recipients Lists
Research Category: Endocrine Disruptors , Environmental Engineering , Water
Objective:
Working closely with local departments of public health partners, we plan to achieve the following. Objective 1: Develop optimal sampling strategies for wastewater monitoring networks for the detection of emerging pandemic pathogens; Objective 2: Develop and test a framework for adapting the wastewater monitoring strategies based on characteristics of the pathogen, its infection, transmission processes, and target populations; Objective 3: Develop a secure data management platform to provide actionable wastewater monitoring information to public health officials and utilities for pandemic control.
Progress Summary:
The first year of the project has been devoted to the first two objectives and the outputs and outcomes are documented below:
- For objective 1, we have been working on a model that combines highway transportation with infectious disease transmission. This modeling effort is led by University of Florida and University of Alabama.
- For objective 2, University of Illinois team has developed sampling methods for locations in the regions with septic tanks and analytical methods for targeting several viruses. The analytical methods range from digital PCR to portable assay.
- For objective 3, University of Illinois team has developed a template of a dashboard of different viruses and related public health intervention and is currently working with public health agencies to improve it.
Future Activities:
Objective 1: Validate the models with data from Objective 2
Objective 2: Complete analyzing the wastewater samples for different viruses and transferring them into a dashboard.
Objective 3: We will continue to work with the participatory research team to prioritize attributes of a wastewater surveillance dashboard and to determine use cases for its application.
Journal Articles on this Report : 1 Displayed | Download in RIS Format
| Other project views: | All 4 publications | 4 publications in selected types | All 4 journal articles |
|---|
| Type | Citation | ||
|---|---|---|---|
|
|
Oh C, Xun G, Lane ST, Petrov VA, Zhao H, Nguyen TH. Portable, single nucleotide polymorphism-specific duplex assay for virus surveillance in wastewater. Science of the Total Environment 2024;912:168701. |
R840487 (2024) |
Exit |
Supplemental Keywords:
wastewater, virus, pathogen, infection, risk, secured data platformProgress and Final Reports:
Original AbstractThe perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.