Grantee Research Project Results
2021 Progress Report: Innovative methodology based on a non-targeted screening approach combined with activity patterns for estimation of soil and dust ingestion rate in children.
EPA Grant Number: R840199Title: Innovative methodology based on a non-targeted screening approach combined with activity patterns for estimation of soil and dust ingestion rate in children.
Investigators: Quinete, Natalia , Gardinali, Piero , Bagner, Daniel , George, Florence
Institution: Florida International University
EPA Project Officer: Hahn, Intaek
Project Period: June 1, 2021 through May 6, 2025
Project Period Covered by this Report: June 1, 2021 through May 31,2022
Project Amount: $1,217,193
RFA: Estimating Childrens Soil and Dust Ingestion Rates for Exposure Science (2020) RFA Text | Recipients Lists
Research Category: Children's Health , Endocrine Disruptors , Human Health
Objective:
Aim 1: Development of a non-targeted screening approach to estimate soil and dust ingestion by children.
Aim 2: Activity pattern study to estimate soil and dust ingestion by children.
Aim 3: Statistical calculations combining both approaches for accurate estimation of soil and dust ingestion rate by children.
Progress Summary:
- The QAPP document was submitted and has been approved
- Two post-doctoral research associates (Dr. Joseph Cox and Dr. Danni Cui) and a project coordinator (Emily Meijas) for recruitment (Obj 2) have been hired to work on the project
- Surveys and questionnaires were created and setup in REDCap
- Non-targeted screening methods for different matrices (urine, soil, dust, food and water) have been established and tested
- Completed initial training of undergraduate students to help with family recruitment at Nicklaus Children’s Hospital
- Project logo, flyers, google voice phone number, email account, and SharePoint for the project were created
- We recruited over one-third of our targeted enrollment (i.e., 34 families) to participate, and a total of 15 families have completed the first two sets of sample collection and surveys
- Publications/Presentations: Acceptance of an abstract to SETAC 2022 in Pittsburgh for platform presentation of the preliminary work titled “Identifying children’s exposure to chemicals through soil and dust ingestion using non-targeted analysis approaches
Future Activities:
1. Continue recruitment efforts to enroll a total of 90 children
2. Continue analyzing samples to elucidate children’s chemical exposure and identification of potential soil and dust tracers.
3. Initiate statistical studies to evaluate the model to be used for soil and dust ingestion rate.
Journal Articles:
No journal articles submitted with this report: View all 1 publications for this projectSupplemental Keywords:
NTA, drinking water, food, urine, Florida, underrepresented population, SHEDS-HTProgress and Final Reports:
Original AbstractThe perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.