Grantee Research Project Results
Publications submitted after final report for Center:
Human Models for Analysis of Pathways (H MAPs) Center
Grant Number R835737
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Reference Type | Citation | Progress Report Year (Date Added to Report) | Document Sources |
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Abstract | Ghanian Z, Mehvar S, Jamali N, Sheibani N, Ranji M. Time-lapse microscopy of oxidative stress demonstrates metabolic sensitivity of retinal pericytes under high glucose condition. JOURNAL OF BIOPHOTONICS 2018;11(9):e201700289 |
R835737 (Final) (07/25/23) |
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Abstract | Li C, Yu J, Schehr J, Berry S, Leal T, Lang J, Beebe D. Exclusive Liquid Repellency: An Open Multi-Liquid-Phase Technology for Rare Cell Culture and Single-Cell Processing. APPLIED MATERIALS & INTERFACES 2018;10(20):17065-17070 |
R835737 (Final) (07/25/23) |
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Abstract | Li C, Yu J, Paine P, Juang D, Berry S, Beebe D. Double-exclusive liquid repellency (double-ELR): an enabling technology for rare phenotype analysis. LAB ON A CHIP 2018;18(18):2710-2719 |
R835737 (Final) (07/25/23) |
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Abstract | Saghiri M, Asatourian A, Nguyn E, Wang S, Sheibani N. Hydrogel Arrays and Choroidal Neovascularization Models for Evaluation of Angiogenic Activity of Vital Pulp Therapy Biomaterials. JOURNAL OF ENDODONTICS 2018;44(5):773-779 |
R835737 (Final) (07/25/23) |
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Abstract | McGee G. Quantifying Exposome-Health Associations with Bayesian Multiple Index Models. Instituto de Salud Global de Barcelona. Spain 2023. |
R839278 (2019) (04/13/23) |
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Journal Article | Aisenbrey E, Murphy W. Synthetic alternatives to Matrigel. Nature Reviews Materials 2020 |
R835737 (Final) (06/18/20) |
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Journal Article | Bakooshli M, Lippmann E, Mulcahy B, Iyer N, Nguyen C, Tung K, Stewart B, van den Dorpel H, Fuehrmann T, Gilbert P, Shoichet M, Bigot A, Pegoraro E, Ahn H, Ginsberg H, Zhen M, Ashton R, Gilbert P. A 3D culture model of innervated human skeletal muscle enables studies of the adult neuromuscular junction. DEVELOPMENTAL BIOLOGHY, STEM CELLS AND REGENERATIVE MEDICINE 2019;8(e44530) |
R835737 (Final) (07/25/23) |
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Journal Article | Chien H, MacKay D. Assessing effects of model complexity and structure on predictions of hydrological responses using serial and parallel model design. HYDROLOGICAL PROCESSES 2020;34(2):404-419. |
R830669 (Final) (06/07/22) |
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Journal Article | Clements AE, Groves ER, Chamberlain CS, Vanderby R, Murphy WL. Microparticles locally deliver active interleukin-1 receptor antagonist in vivo. Advanced Healthcare Materials 2018;7(16):1800263. |
R835737 (Final) (07/25/23) |
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Journal Article | Estevez-Silva M, Sreeram A, Cuskey S, Fedorchak N, Layer N, Ashton R. Single-injection ex ovo transplantation method for broad spinal cord engraftment of human pluripotent stem cell-derived motor neurons. JOURNAL OF NEUROSCIENCE METHODS 2018;298:16-23 |
R835737 (Final) (07/26/23) |
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Journal Article | Falero-Perez J, Sorenson C, Sheibani N. Cyp1b1-deficient retinal astrocytes are more proliferative and migratory and are protected from oxidative stress and inflammation. AMERICAN JOURNAL OF PHYSIOLOGY 2019;306(6):C767-C781 |
R835737 (Final) (07/26/23) |
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Journal Article | Gotkowitz M, Bradbury K, Borchardt M, Zhu J, Spencer S. Effects of Climate and Sewer Condition on Virus Transport to Groundwater. ENVIRONMENTAL SCIENCE & TECHNOLOGY 2016;50(16):8497-8504. |
R834869 (Final) (06/07/22) |
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Journal Article | Iyer N, Shin J, Cuskey S, Tian Y, Nicol N, Doersch T, Seipel F, McCalla S, Roy S, Ashton R. Modular derivation of diverse, regionally discrete human posterior CNS neurons enables discovery of transcriptomic patterns. SCIENCE ADVANCES 2022;8(39):eabn7430 |
R835737 (Final) (01/13/23) |
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Journal Article | Johnson B, VItek R, Morgan M, Fink D, Beames T, Geiger P, Beebe D, Lipinski R. A Microphysiological Approach to Evaluate Effectors of Intercellular Hedgehog Signaling in Development. Frontiers in Cell and Developmental Biology 2021;9:71. |
R835737 (Final) (03/25/21) |
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Journal Article | Kauschik G, Gupta K, Harms V, Torr E, Evans J, Johnson H, Soref C, Acevedo-Acevedo S, Antosiewicz-Bourget J, Mamott D. Engineered Perineural Vascular Plexus for Modeling Developmental Toxicity. Advanced Healcare Materials 2020;(2000825). |
R835737 (Final) (07/17/20) |
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Journal Article | Khalil A, Yu X, Umhoefer J, Chamberlain C, COnnie S, Wildenauer L, Diarra G, Hacker T, Murphy W. Single-dose mRNA therapy via biomaterial-mediated sequestration of overexpressed proteins. Science Advances 2020;6(27):eaba2422. |
R835737 (Final) (08/13/20) |
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Journal Article | Knight GT, Lundin BF, Iyer N, Ashton LMT, Sethares WA, Willett RM, Ashton RS. Engineering induction of singular neural rosette emergence within jPSC-derived tissues. eLIFE 2018;7:e37549 (23 pp.). |
R835737 (Final) (07/25/23) |
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Journal Article | KOwalski K, Auerbach J, Martinies S, Starling A, Moore B, Dabelea D, Magzamen S. Neighborhood Walkability, Historical Redlining, and Childhood Obesity in Denver, Colorado. JOURNAL OF URBAN HEALTH-BULLETIN OF THE NEW YORK ACADEMY OF MEDICINE 2023;Early Access |
R839278 (2021) (02/02/23) |
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Journal Article | Lavine JA, Farnoodian M, Wang S, Darjatmoko SR, Wright LS, Gamm DM, Ip MS, Sorenson CM, Sheibani N. β2-adrenergic receptor antagonism attenuates CNV through inhibition of VEGF and IL-6 expression. Investigative Ophthalmology & Visual Science 2017;58(1):299-308. |
R835737 (Final) (07/25/23) |
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Journal Article | Lei J, Murphy W, Temenoff J. Combination of Heparin Binding Peptide and Heparin Cell Surface Coatings for Mesenchymal Stem Cell Spheroid Assembly. BIOCONJUGATE CHEMISTRY 2018;29(4):878-884 |
R835737 (Final) (07/25/23) |
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Journal Article | Lewis S, Takimoto T, Mehrvar S, Higuchi H, Doebley A, Stokes G, Sheibani N, Ideda S, Ranji M, Ikeda A. The effect of Tmem135 overexpression on the mouse heart. PLOS ONE 2018;13(8):e0201986 |
R835737 (Final) (07/25/23) |
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Journal Article | Li C, Hurley A, Hu W, Warrick J, Lozano G, Ayuso J, Pan W, Handlesman J, Beebe D. Social motility of biofilm-like microcolonies in a gliding bacterium. Nature Communications 2021;12(1). |
R835737 (Final) (11/05/21) |
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Journal Article | Mahony C, Ashton R, Birk B, Boobis A, Cull T, Datson G, Ewart L, Knudsen T, Manou I, Maurer-Stroh S. New ideas for non-animal approaches to predict repeated-dose systemic toxicity:Report from an EPAA Blue Sky Workshop. Regulatory Toxicology and Pharmacology 2020;114(UNSP 104668). |
R835737 (Final) (07/17/20) |
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Journal Article | Majumder J, Torr E, Aisenbrey E, Lebakken C, Favreau P, Richards W, Yin Y, Chang Q, Murphy W. Human induced pluripotent stem cell-derived planar neural organoids assembled on synthetic hydrogels. JOURNAL OF TISSUE ENGINEERING 2024;15(20417314241230633) |
R835737 (Final) (03/01/24) |
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Journal Article | Martinies S, Hoskovec L, Wilson A, Moore B, Starling A, Allshouse W, Adgate J, Dabelea D, Magzamen S. Using non-parametric Bayes shrinkage to assess relationships between multiple environmental and social stressors and neonatal size and body composition in the Healthy Start cohort. ENVIRONMENTAL HEALTH 2022;21(1):111 |
R839278 (2021) (12/01/22) |
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Journal Article | McDonald B, McKeen S, Cui Y, Agmanadov R, Kim S, Frost G, Pollack I, Peischl J, Holloway J, Graus M, Warneke C, Gilman J, de Gouw J, Kaiser J, Keutsch F, Hanisco T, Wolfe G, Trainer M. Modeling Ozone in the Eastern using a Fuel-Based Mobile Source Emissions Inventory. ENVIRONMENTAL SCIENCE & TECHNOLOGY 2018;52(13):7360-7370. |
R835406 (Final) (06/21/22) |
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Journal Article | McGee G, Wilson A, Webster T, Coull B. Bayesian multiple index models for environmental mixtures. BIOMETRICS 2021;1(3). |
R835872 (2020) (07/07/22) R839278 (2020) (07/07/22) |
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Journal Article | Mezu-Ndubuisi O, Wang Y, Schoephoerster J, Falero_Perez J, Zaitoun I, Sheibani, Gong S. Intravitreal Delivery of VEGF-A(165)-loaded PLGA Microparticles Reduces Retinal Vaso-Obliteration in an In Vivo Mouse Model of Retinopathy of Prematurity. CURRENT EYE RESEARCH 2018;44(Full Text HTML):275-286 |
R835737 (Final) (07/25/23) |
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Journal Article | Molugy K, Harkness T, Carlson-Tevermer J, Prestil R, Piscopo N, Seymour S, Knight G, Ashton R, Saha K. Tracking and Predicting Human Somatic Cell Reprogramming Using Nuclear Characteristics. BIOPHYSICAL JOURNAL 2020;118(9):2086-2102. |
R835737 (Final) (05/26/20) |
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Journal Article | Morgan M, Schuler L, Ciciliano J, Johnson B, Alarid E, Beebe D. Modeling chemical effects on breast cancer: the importance of the microenvironment in vitro. Integrative Biology 2020;12(2):21-33 |
R835737 (Final) (07/17/20) |
not available |
Journal Article | Schwantes R, Lacey F, Tilmes S, Emmons L, Lauritzen P, Walters S, Callaghan P, Zarzycki C, Barth M, Jo D, Duseong S. Evaluating the Impact of Chemical Complexity and Horizontal Resolution on Tropospheric Ozone Over the Conterminous US With a Global Variable Resolution Chemistry Model. JOURNAL OF ADVANCES IN MODELING EARTH SYSTEMS 2019;14(6):e2021MS002889. |
R835406 (Final) (07/05/22) |
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Journal Article | Seirup M, Chu L, Sengupta S, Leng N, Browder H, Kapadia K, Shafer C, Duffin B, Elwell A, Bolin J. Reproducibility across single-cell RNA-seq protocols for spatial ordering analysis. PLOS One 2020;15(9). |
R835737 (Final) (11/05/20) |
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Journal Article | Seirup M, Sengupta S, Swanson S, McIntosh B, Collins M, Cu L, Cheng Z, Gorkin D, Duffin B, Bolin J, Argus C, Stewart R, Thompson J. Rapid changes in chromatin structure during dedifferentiation of primary hepatocytes in vitro. GENOMICS 2022;114(3):110330. |
R835737 (Final) (08/11/22) |
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Journal Article | Tseng M, Fu Q, Yokel R, Lor K, Fernandez-Botran G, Deng Z, Graham U, Butterfield D, Grulke E. Persistent Hepatic Structural Alterations Following Nanoceria Vascular Infusion in the Rat. TOXIC PATHOLOGY 2013;42(6):984-996 |
R833372 (Final) (07/18/23) |
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Journal Article | Virumbrales-Munoz M, Ayuso J, Lacueva A, Randelovic T, Livingston M, Beebe D, Olivan S, Pereboom D, Doblare M, Fernandez L. Enabling cell recovery from 3D cell culture microfluidic devices for tumour microenvironment biomarker profiling. Scientific Reports 2020;10(1):757. |
R835737 (Final) (08/13/20) |
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Journal Article | Xie A, Zacharias N, Binder B, Murphy W. Controlled aggregation enhances immunomodulatory potential of mesenchymal stromal cell aggregates. Stem Cells Translational Medicine 2021;1(18). |
R835737 (Final) (04/21/21) |
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Journal Article | Clements AE, Leiferman EM, Chamberlain CS, Vanderby R, Murphy WL. Addition of mineral coated microparticles to soluble interleukin-1 receptor antagonist injected subcutaneously improves and extends systemic interleukin-1 inhibition. Advanced Therapeutics 2018;1(7):1800048. |
R835737 (Final) (07/25/23) |
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Journal Article | Mork D, Kioumourtzoglou MA, Weisskopf M, Coull BA, Wilson A. Heterogeneous Distributed Lag Models to Estimate Personalized Effects of Maternal Exposures to Air Pollution. ARXIV PREPRINT ARXIV 2019;13763. |
R835872 (Final) (12/21/23) R839278 (2019) (04/13/23) R839278 (Final) (12/21/23) |
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Journal Article | Martenies SE, Akherati A, Jathar S, Magzamen S. Health and environmental justice implications of retiring two coal‐fired power plants in the southern Front Range region of Colorado. GeoHealth 2019;3(9):266-283. |
R839278 (2019) (06/19/20) |
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Journal Article | Khalil AS, Xie AW, Johnson HJ, Murphy WL. Sustained release and protein stabilization reduce the growth factor dosage required for human pluripotent stem cell expansion. Biomaterials 2020:120007. |
R835737 (Final) (05/26/20) |
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Journal Article | Hoskovec L, Benka-Coker W, Severson R, Magzman S, Wilson A. Model choice for estimating the association between exposure to chemical mixtures and health outcomes:A simulation study. PLOS ONE 2021;16(3):e0249236. |
R839278 (2019) (04/13/23) |
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Journal Article | Bergin RA, Harkey M, Hoffman A, Moore RH, Anderson B, Beyersdorf A, Ziemba L, Thornhill L, Winstead E, Holloway T, Bertram TH. Observation-based constraints on modeled aerosol surface area:implications for heterogeneous chemistry. Atmospheric Chemistry and Physics 2022;22:15449–68. |
R840006 (2022) (01/06/23) R840006 (2023) (12/08/23) |
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Report | McGee G. Quantifying Exposome-Health Associations with Bayesian Multiple Index Models. Instituto de Salud Global de Barcelona, Spain, April 2021, 20.500.12592/nm03k7. |
R839278 (2021) (03/30/23) |
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.