Skip to main content
U.S. flag

An official website of the United States government

Here’s how you know

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

HTTPS

Secure .gov websites use HTTPS
A lock (LockA locked padlock) or https:// means you have safely connected to the .gov website. Share sensitive information only on official, secure websites.

  • Environmental Topics
  • Laws & Regulations
  • Report a Violation
  • About EPA
Contact Us

Grantee Research Project Results

Publications Details for Grant Number R835165

Multi-Sensor Reporter Cell Technology to Assess Hazard Involving Endocrine Signaling Pathways

RFA: Developing High-Throughput Assays for Predictive Modeling of Reproductive and Developmental Toxicity Modulated Through the Endocrine System or Pertinent Pathways in Humans and Species Relevant to Ecological Risk Assessment (2011)

Other Views

  • All
    Publications
  • Selected
    Publication Types
  • Journal
    Articles
  • Publications Submitted
    After Final Report
  • Redisplay this page with
    Reference Title, Journal, and Author Columns
  • Display this Page
    in RIS Format
Journal Article (7)
Presentation (19)
Reference Type Citation Progress Report Year Document Sources
Journal Article Adoteye K, Banks HT, Cross K, Eytcheson S, Flores KB, LeBlanc GA, Nguyen T, Ross C, Smith E, Stemkovski M, Stokely S. Statistical validation of structured population models for Daphnia magna. Mathematical Biosciences 2015;266:73-84. R835165 (Final)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Abstract: ScienceDirect-Abstract
    Exit
Journal Article Adoteye K, Banks HT, Flores KB, LeBlanc GA. Estimation of time-varying mortality rates using continuous models for Daphnia magna. Applied Mathematics Letters 2015;44:12-16. R835165 (Final)
  • Abstract: ScienceDirect-Abstract
    Exit
Journal Article Kakaley EK, Wang HY, LeBlanc GA. Agonist-mediated assembly of the crustacean methyl farnesoate receptor. Scientific Reports 2017;7:45071 (9 pp.). R835165 (Final)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Full-text: Scientific Reports-Full Text HTML
    Exit
  • Abstract: Scientific Reports-Abstract
    Exit
  • Other: Scientific Reports-Full Text PDF
    Exit
Journal Article LeBlanc GA, Medlock EK. Males on demand: the environmental-neuro-endocrine control of male sex determination in daphnids. The FEBS Journal 2015;282(21):4080-4093. R835165 (2015)
R835165 (Final)
  • Abstract from PubMed
  • Full-text: Wiley Online-Full Text HTML
    Exit
  • Abstract: Wiley Online-Abstract
    Exit
  • Other: Wiley Online-Full Text PDF
    Exit
Journal Article Medlock Kakaley EK, Eytcheson SA, LeBlanc GA. Ligand-mediated receptor assembly as an endpoint for high-throughput chemical toxicity screening. Environmental Science & Technology 2017;51(16):9327-9333. R835165 (Final)
  • Full-text from PubMed
  • Abstract from PubMed
  • Associated PubMed link
  • Full-text: ACS-Full Text HTML
    Exit
  • Abstract: ACS-Abstract
    Exit
  • Other: ACS-Full Text PDF
    Exit
Journal Article Rutter E, Banks H, LeBlanc G, Flores K. Continuous Structured Population Models for Daphnia magna. BULLETIN OF MATHEMATICAL BIOLOGY 2017;79:2627-2648 R835165 (Final)
  • Full-text from PubMed
  • Full-text: Springer Link - Full Text HTML
    Exit
Journal Article Wang Y, Kwon G, An L, Holmes CN, Haeba M, LeBlanc GA. Differential interactions of the flame retardant triphenyl phosphate within the PPAR signaling network. MOJ Toxicology 2016;2(3):00039 (11 pp.). R835165 (Final)
  • Full-text: MOJT-Full Text HTML
    Exit
  • Abstract: MOJT-Abstract
    Exit
  • Other: MOJT-Full Text PDF
    Exit
Presentation An L, Ectcheson S, Holmes C, Kwon G, Medlock E, Wang Y. High-throughput assays to assess interactive effects of chemicals on endocrine signaling pathways. Presented at the Society of Environmental Toxicology and Chemistry (SETAC) North America Focus Topic Meeting: Endocrine Disruption, U.S. Environmental Protection Agency, Research Triangle Park, NC, February 4-6, 2014. R835165 (2015)
R835165 (Final)
not available
Presentation Holmes CN, LeBlanc GA. Integrating synergy into additive models of chemical mixtures toxicity. Presented at the Carolinas Society of Environmental Toxicology and Chemistry (CSETAC) Annual Meeting, Raleigh, NC, March 2013. R835165 (Final)
not available
Presentation Holmes CN, LeBlanc GA. Insect growth-regulating insecticides differentially activates the PPAR signaling network. Presented at the 53rd Annual Meeting of the Society of Toxicology, Phoenix, AZ, March 23-27, 2014. R835165 (Final)
not available
Presentation Holmes CN, LeBlanc GA. Insect growth-regulating insecticides differentially activate the PPAR signaling network. Presented at the 54th Annual Meeting of the Society of Toxicology, San Diego, CA, March 22-26, 2015 R835165 (2014)
R835165 (2015)
R835165 (Final)
not available
Presentation Holmes CN, Kwon G, Wang Y, An L, LeBlanc GA. Ligand-dependent receptor assembly as an endpoint for the high-throughput screening of chemicals for endocrine activity. Presented at the Society of Environmental Toxicology and Chemistry (SETAC) North America 36th Annual Meeting, Salt Lake City, UT, November 1-5, 2015. R835165 (2015)
R835165 (Final)
not available
Presentation Holmes CN, Kwon G, Wang Y, An L, LeBlanc GA. Bioluminescence energy resonance transfer: an innovative technology for evaluating chemical interactions with nuclear receptors. Presented at the Society of Toxicology Future Tox III Meeting, Arlington, VA, November 19-20, 2015. R835165 (2015)
R835165 (Final)
not available
Presentation LeBlanc GA. Multi-sensor reporter cell technology to assess hazard involving endocrine signaling pathways. Presented at the U.S. Environmental Protection Agency, Washington DC, 2012. R835165 (2013)
R835165 (Final)
not available
Presentation LeBlanc GA, Wang YH, Holmes CN, Kwon G, Medlock EK. A transgenerational endocrine signaling pathway in crustacea. Presented at the Carolinas Society of Environmental Toxicology and Chemistry (CSETAC) Meeting, Raleigh, NC, March 2013. R835165 (2012)
R835165 (Final)
not available
Presentation LeBlanc GA. Endocrine disruption beyond the estrogen, androgen, and thyroid signaling pathways. Presented via a webinar sponsored by the U.S. Environmental Protection Agency, Washington DC, 2013. R835165 (2013)
R835165 (Final)
not available
Presentation LeBlanc GA. Sex on demand: environmental sex determination in crustacea. Presented at the University of North Carolina at Wilmington, Wilmington, NC, 2013. R835165 (2013)
R835165 (Final)
not available
Presentation LeBlanc GA. Emerging targets of endocrine disruption: the xenocrine system. Presented at the Society of Environmental Toxicology and Chemistry (SETAC) North America Focused Topic Meeting: Endocrine Disruption, U.S. Environmental Protection Agency, Research Triangle Park, NC, February 4-6, 2014. R835165 (2013)
R835165 (Final)
not available
Presentation Medlock EK, LeBlanc GA. Reproductive and developmental signaling pathway in crustaceans. Presented at the Society of Environmental Toxicology and Chemistry (SETAC) North America 34th Annual Meeting, Nashville, TN, November 17-21, 2013. R835165 (2012)
not available
Presentation Medlock EK, LeBlanc GA. Activation of a sex determination signaling cascade in crustaceans. Presented at the Carolinas Chapter of the Society of Environmental Toxicology and Chemistry (CSETAC) Annual Meeting, Clemson SC, April 2014. R835165 (2014)
R835165 (Final)
not available
Presentation Medlock EK, LeBlanc GA. Activation and disruption of a crustacean reproductive signaling pathway. Presented at the 35th Annual Meeting of the Society of Environmental Toxicology and Chemistry (SETAC) North America, Vancouver, British Columbia, Canada, November 9-13, 2014. R835165 (2014)
R835165 (Final)
not available
Presentation Medlock EK. Males on demand: the environmental–neuro-endocrine control of male sex determination in daphnids. Podcast presented via The FEBS Journal, August 26, 2015. R835165 (2015)
R835165 (Final)
  • Other: PlayerFM-Podcast Playback
    Exit
Presentation Medlock EK, LeBlanc GA. Deciphering an environmental-endocrine signaling pathway for the identification of efficacious screening endpoints. Presented at the Society of Environmental Toxicology and Chemistry (SETAC) North America 36th Annual Meeting, Salt Lake City, UT, November 1-5, 2015. R835165 (2015)
R835165 (Final)
not available
Presentation Medlock EK, LeBlanc GA. Bioluminescence resonance energy transfer (BRET) as an approach for high-throughput screening of chemicals for toxicity. Presented at the North Carolina State University Graduate Student Symposium, Raleigh, NC, 2015. R835165 (Final)
not available
Presentation Medlock E, LeBlanc GA. A novel approach for high-throughput screening of potential crustacean endocrine disrupting chemicals. Poster presented at the North Carolina State University 10th Annual Graduate Student Research Symposium, Raleigh, NC, March 25, 2015 (Poster No. 118). R835165 (2015)
  • Abstract: NCSU-2015 Symposium Abstracts
    Exit
Presentation LeBlanc GA. Novel modes of endocrine action and disruption. Presented at the 6th Society of Environmental Toxicology and Chemistry (SETAC) Europe Special Science Symposium: Environmental Endocrine Disruptor Testing and Evaluation, Brussels, Belgium, October 24-25, 2012. R835165 (Final)
not available

Top of Page

The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

Site Navigation

  • Grantee Research Project Results Home
  • Grantee Research Project Results Basic Search
  • Grantee Research Project Results Advanced Search
  • Grantee Research Project Results Fielded Search
  • Publication search
  • EPA Regional Search

Related Information

  • Search Help
  • About our data collection
  • Research Grants
  • P3: Student Design Competition
  • Research Fellowships
  • Small Business Innovation Research (SBIR)
Contact Us to ask a question, provide feedback, or report a problem.
Last updated April 28, 2023
United States Environmental Protection Agency

Discover.

  • Accessibility
  • Budget & Performance
  • Contracting
  • EPA www Web Snapshot
  • Grants
  • No FEAR Act Data
  • Plain Writing
  • Privacy
  • Privacy and Security Notice

Connect.

  • Data.gov
  • Inspector General
  • Jobs
  • Newsroom
  • Open Government
  • Regulations.gov
  • Subscribe
  • USA.gov
  • White House

Ask.

  • Contact EPA
  • EPA Disclaimers
  • Hotlines
  • FOIA Requests
  • Frequent Questions

Follow.