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Grantee Research Project Results

Publications Details for Grant Number R833137

Risk Assessment of Food Allergenicity by a Data Base Approach

RFA: Biotechnology: Potential Allergenicity of Genetically Engineered Foods (2006)

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Abstract (2)
Journal Article (13)
Presentation (30)
Working Group/Panel (1)
Reference Type Reference Title Journal Author Citation Progress Report Year Document Sources
Abstract Cross reactivity in mountain cedar-tomato oral allergy syndrome. None Bonds RS, Tiwari R, Ning B, Czerwinski EW, Goldblum RM, Midoro-Horiuti T Bonds RS, Tiwari R, Ning B, Czerwinski EW, Goldblum RM, Midoro-Horiuti T. Cross reactivity in mountain cedar-tomato oral allergy syndrome. Journal of Allergy and Clinical Immunology 2007;119(1):S113 R833137 (Final)
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Abstract Analysis for IgE epitopes of Jun a 1 using random peptide display library. None Midoro-Horiuti T, Tiwari R, Negi S, Ning B, Schein C, Braun W, Goldblum R Midoro-Horiuti T, Tiwari R, Negi S, Ning B, Schein C, Braun W, Goldblum R. Analysis for IgE epitopes of Jun a 1 using random peptide display library. Japanese Journal of Allergology 2007;56(8-9):1108. R833137 (Final)
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Journal Article A structural basis for food allergy: the role of cross-reactivity. None Bonds RS, Midoro-Horiuti T, Goldblum R Bonds RS, Midoro-Horiuti T, Goldblum R. A structural basis for food allergy: the role of cross-reactivity. Current Opinion in Allergy and Clinical Immunology 2008;8(1):82-86. R833137 (Final)
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Journal Article Isolation and characterization of native Cry j 3 from Japanese cedar (Cryptomeria japonica) pollen. None Fujimura T, Futamura N, Midoro-Horiuti T, Togawa A, Goldblum RM, Yasueda H, Saito A, Shinohara K, Masuda K, Kurata K, Sakaguchi M Fujimura T, Futamura N, Midoro-Horiuti T, Togawa A, Goldblum RM, Yasueda H, Saito A, Shinohara K, Masuda K, Kurata K, Sakaguchi M. Isolation and characterization of native Cry j 3 from Japanese cedar (Cryptomeria japonica) pollen. Allergy 2007;62(5):547-533. R833137 (Final)
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Journal Article Structural analysis of linear and conformational epitopes of allergens. None Ivanciuc O, Schein CH, Garcia T, Oezguen N, Negi SS, Braun W Ivanciuc O, Schein CH, Garcia T, Oezguen N, Negi SS, Braun W. Structural analysis of linear and conformational epitopes of allergens. Regulatory Toxicology and Pharmacology 2009;54(3 Suppl):S11-S19. R833137 (2008)
R833137 (Final)
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Journal Article Characteristic motifs for families of allergenic proteins. None Ivanciuc O, Garcia T, Torres M, Schein CH, Braun W Ivanciuc O, Garcia T, Torres M, Schein CH, Braun W. Characteristic motifs for families of allergenic proteins. Molecular Immunology 2009;46(4):559-568. R833137 (2008)
R833137 (Final)
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Journal Article The property distance index PD predicts peptides that cross-react with IgE antibodies. None Ivanciuc O, Midoro-Horiuti T, Schein CH, Xie L, Hillman GR, Goldblum RM, Braun W Ivanciuc O, Midoro-Horiuti T, Schein CH, Xie L, Hillman GR, Goldblum RM, Braun W. The property distance index PD predicts peptides that cross-react with IgE antibodies. Molecular Immunology 2009;46(5):873-883. R833137 (2008)
R833137 (Final)
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Journal Article Plant-expressed recombinant mountain cedar allergen Jun a 1 is allergenic and has limited pectate lyase activity. None Liu Z, Bhattacharyya S, Ning B, Midoro-Horiuti T, Goldblum RM, Mort A, Czerwinski EW, Kearney CM Liu Z, Bhattacharyya S, Ning B, Midoro-Horiuti T, Czerwinski EW, Goldblum RM, Mort A, Kearney CM. Plant-expressed recombinant mountain cedar allergen Jun a 1 is allergenic and has limited pectate lyase activity. International Archives of Allergy and Clinical Immunology 2010;153(4):347-358. R833137 (Final)
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Journal Article The expression of a mountain cedar allergen comparing plant-viral apoplastic and yeast expression systems. None Moehnke MH, Midoro-Horiuti T, Goldblum RM, Kearney CM Moehnke MH, Midoro-Horiuti T, Goldblum RM, Kearney CM. The expression of a mountain cedar allergen comparing plant-viral apoplastic and yeast expression systems. Biotechnology Letters 2008;30(7):1259-1264. R833137 (Final)
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Journal Article Automated detection of conformational epitopes using phage display peptide sequences. None Negi SS, Braun W Negi SS, Braun W. Automated detection of conformational epitopes using phage display peptide sequences. Bioinformatics and Biology Insights 2009;3:71-81. R833137 (2008)
R833137 (Final)
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Journal Article Comprehensive 3D-modeling of allergenic proteins and amino acid composition of potential conformational IgE epitopes. None Oezguen N, Zhou B, Negi SS, Ivanciuc O, Schein CH, Labesse G, Braun W Oezguen N, Zhou B, Negi SS, Ivanciuc O, Schein CH, Labesse G, Braun W. Comprehensive 3D-modeling of allergenic proteins and amino acid composition of potential conformational IgE epitopes. Molecular Immunology 2008;45(14):3740-3747. R833137 (2008)
R833137 (Final)
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Journal Article Bioinformatics approaches to classifying allergens and predicting cross-reactivity. None Schein CH, Ivanciuc O, Braun W Schein CH, Ivanciuc O, Braun W. Bioinformatics approaches to classifying allergens and predicting cross-reactivity. Immunology and Allergy Clinics of North America 2007;27(1):1-27. R833137 (2007)
R833137 (Final)
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Journal Article An allergen portrait gallery: representative structures and an overview of IgE binding surfaces. BIOINFORMATICS AND BIOLOGY INSIGHTS Schein CH, Ivanciuc O, Midoro-Horiuti T, Goldblum RM, Braun W Schein CH, Ivanciuc O, Midoro-Horiuti T, Goldblum RM, Braun W. An allergen portrait gallery: representative structures and an overview of IgE binding surfaces. Bioinformatics and Biology Insights 2010;4:113-125. R833137 (Final)
R834066 (Final)
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Journal Article Validation of a phage display and computational algorithm by mapping a conformational epitope of Bla g 2. None Tiwari R, Negi SS, Braun B, Braun W, Pomes A, Chapman MD, Goldblum RM, Midoro-Horiuti T Tiwari R, Negi SS, Braun B, Braun W, Pomes A, Chapman MD, Goldblum RM, Midoro-Horiuti T. Validation of a phage display and computational algorithm by mapping a conformational epitope of Bla g 2. International Archives of Allergy and Immunology 2012;157(4):323-330. R833137 (Final)
R834823 (2012)
R834823 (2013)
R834823 (Final)
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Journal Article Major mountain cedar allergen, Jun a 1 contains conformational as well as linear IgE epitopes. None Varshney S, Goldblum RM, Kearney C, Watanabe M, Midoro-Horiuti T Varshney S, Goldblum RM, Kearney C, Watanabe M, Midoro-Horiuti T. Major mountain cedar allergen, Jun a 1 contains conformational as well as linear IgE epitopes. Molecular Immunology 2007;44(10):2781-2785. R833137 (Final)
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Presentation The structural biology of allergens. None Braun W Braun W. The structural biology of allergens. Presented at the Oesper Symposium 2010 honoring Kurt Wuethrich (Nobel Prize 2002 in Chemistry), University of Cincinnati, Cincinnati, OH, October 8, 2010. R833137 (Final)
R834823 (2011)
R834823 (Final)
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Presentation Allergen structures in a genomics age. None Braun W Braun W. Allergen structures in a genomics age. Presented at the Keystone Symposium: Structural Genomics: Expanding the Horizons of Structural Biology, Beaver Run Resort, Breckenridge, CO, January 10, 2010. R833137 (Final)
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Presentation Prediction and detection of conformational epitopes of IgE antibodies. None Braun W Braun W. Prediction and detection of conformational epitopes of IgE antibodies. Presented at the 48th Annual Meeting of the Society of Toxicology, Baltimore, MD, March 15-19, 2009. R833137 (Final)
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Presentation Risk assessment of food allergenicity by a data base approach. None Braun W, Goldblum RM, Schein CH, Midoro-Horiuti T, Gendel S Braun W, Goldblum RM, Schein CH, Midoro-Horiuti T, Gendel S. Risk assessment of food allergenicity by a data base approach. Presented at the Health and Environmental Sciences Institute's (HESI) Research to Improve Safety Assessment of Biotechnology Products for Potential Risk of Food Allergy Meeting, Washington, DC, October 15-16, 2008. R833137 (2008)
R833137 (Final)
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Presentation Structural (3-D) comparisons of novel proteins to known allergens. None Braun W Braun W. Structural (3-D) comparisons of novel proteins to known allergens. Presented at the Protein Allergenicity Technical Committee New Methods Workshop, ILSI Health and Environmental Sciences Institute (HESI), Nice, France October 24, 2007. R833137 (Final)
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Presentation Computational analysis of allergenic determinants for the peanut allergen Ara h 3. None Chattopadhyay A, Ivanciuc O, Negi SS, Braun W Chattopadhyay A, Ivanciuc O, Negi SS, Braun W. Computational analysis of allergenic determinants for the peanut allergen Ara h 3. Presented at the 14th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, The University of Texas Medical Branch, Galveston, TX, March 27, 2009. R833137 (Final)
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Presentation Comparative study of IgE epitopes and sequence conservation in the melon allergen Cuc m 2. None Esadze A, Ivanciuc O, Braun W Esadze A, Ivanciuc O, Braun W. Comparative study of IgE epitopes and sequence conservation in the melon allergen Cuc m 2. Presented at the 15th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, Hotel Galvez, Galveston, TX, March 19, 2010. R833137 (Final)
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Presentation Development of an automated process for homology based prediction of protein 3D structure. None Han W, Ivanciuc O, Oezguen N, Braun W Han W, Ivanciuc O, Oezguen N, Braun W. Development of an automated process for homology based prediction of protein 3D structure. Poster presented at the 2010 Medical Student Summer Research Program Poster Session, University of Texas Medical Branch, Galveston, TX, June 24, 2010. R833137 (Final)
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Presentation Application of the Property Distance Index PD for the computer-aided design of IgE binding peptides for the allergen Jun a 1. None Ivanciuc OI, Midoro-Horiuti T, Schein CH, Goldblum RM, Braun W Ivanciuc OI, Midoro-Horiuti T, Schein CH, Goldblum RM, Braun W. Application of the Property Distance Index PD for the computer-aided design of IgE binding peptides for the allergen Jun a 1. Presented at the 12th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, University of Texas Medical Branch Galveston, Galveston, TX, May 18-19, 2007. R833137 (Final)
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Presentation AllerML: ontology and markup language for allergens and for structural biology studies of allergenicity. None Ivanciuc O, Power TD, Gendel SM, Schein CH, Braun W Ivanciuc O, Power TD, Gendel SM, Schein CH, Braun W. AllerML: ontology and markup language for allergens and for structural biology studies of allergenicity. Presented at the 13th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, University of Texas Medical Branch, Galveston, TX, May 16-17, 2008. R833137 (Final)
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Presentation Machine learning for peptide cross-reactivity with the mountain cedar allergen Jun a 1. None Ivanciuc O, Midoro-Horiuti T, Schein CH, Goldblum RM, Braun W Ivanciuc O, Midoro-Horiuti T, Schein CH, Goldblum RM, Braun W. Machine learning for peptide cross-reactivity with the mountain cedar allergen Jun a 1. Presented at the 15th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, Hotel Galvez, Galveston, TX, March 19, 2010. R833137 (Final)
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Presentation A new method to evaluate and combine 3D templates for homology modeling. None Lu W, Braun W Lu W, Braun W. A new method to evaluate and combine 3D templates for homology modeling. Presented at the 15th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, Hotel Galvez, Galveston, TX, March 19, 2010. R833137 (Final)
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Presentation Development of new immunomodulatory agents for cedar pollen allergy. None Midoro-Horiuti T, Ning B, Goldblum RM Midoro-Horiuti T, Ning B, Goldblum RM. Development of new immunomodulatory agents for cedar pollen allergy. Presented at the Annual Meeting of the American College of Allergy, Asthma and Immunology, Miami, FL, November 4-8, 2009. R833137 (Final)
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Presentation Use of random peptide display and novel bioinformatics algorithm to detect conformational epitopes of Jun a 1, the major allergen of mountain cedar pollen. None Midoro-Horiuti T, Tiwari R, Negi SS, Schein CH, Ning B, Goldblum RM, Braun W Midoro-Horiuti T, Tiwari R, Negi SS, Schein CH, Ning B, Goldblum RM, Braun W. Use of random peptide display and novel bioinformatics algorithm to detect conformational epitopes of Jun a 1, the major allergen of mountain cedar pollen. Presented at the Federation of Clinical Immunology Societies (FOCIS) Meeting, San Diego, CA, June 7-11, 2007. R833137 (Final)
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Presentation Use of random peptide display and novel bioinformatics algorithm to detect conformational epitopes of Jun a 1, the major allergen of mountain cedar pollen. None Midoro-Horiuti T, Tiwari R, Negi S, Ning B, Schein C, Braun W, Goldblum R Midoro-Horiuti T, Tiwari R, Negi S, Ning B, Schein C, Braun W, Goldblum R. Use of random peptide display and novel bioinformatics algorithm to detect conformational epitopes of Jun a 1, the major allergen of mountain cedar pollen. Presented at the American Society for Clinical Investigation/Association of American Physicians Joint Meeting, Chicago, IL, April 13-15, 2007. R833137 (Final)
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Presentation Mapping conformational epitopes on protein surfaces using phage display libraries. None Negi SS, Braun W Negi SS, Braun W. Mapping conformational epitopes on protein surfaces using phage display libraries. Presented at the 12th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, University of Texas Medical Branch Galveston, Galveston, TX, May 18-19, 2007. R833137 (Final)
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Presentation EpiSearch: a new method for mapping conformational epitopes using peptide mimics from phage display libraries. None Negi SS, Tiwari R, Midoro-Horiuti T, Goldblum RA, Braun W Negi SS, Tiwari R, Midoro-Horiuti T, Goldblum RA, Braun W. EpiSearch: a new method for mapping conformational epitopes using peptide mimics from phage display libraries. Presented at the 14th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, The University of Texas Medical Branch Galveston, Galveston, TX, March 27, 2009. R833137 (Final)
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Presentation Prediction of allergen cross-reactivity using structural bioinformatics methods. None Negi SS, Oezguen N, Braun W Negi SS, Oezguen N, Braun W. Prediction of allergen cross-reactivity using structural bioinformatics methods. Presented at the 15th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, Hotel Galvez, Galveston, TX, March 19, 2010. R833137 (Final)
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Presentation EpiSearch: a new method for mapping conformational epitopes using peptide mimics from phage display libraries. None Negi S, Tiwari R, Midoro-Horiuti T, Goldblum RM, Braun W Negi S, Tiwari R, Midoro-Horiuti T, Goldblum RM, Braun W. EpiSearch: a new method for mapping conformational epitopes using peptide mimics from phage display libraries. Presented at the 13th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, University of Texas Medical Branch Galveston, Galveston, TX, May 16-17, 2008. R833137 (Final)
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Presentation Homology modeling of allergenic proteins and surface analysis of known epitopes. None Oezguen N, Zhou B, Negi SS, Ivanciuc OI, Braun W Oezguen N, Zhou B, Negi SS, Ivanciuc OI, Braun W. Homology modeling of allergenic proteins and surface analysis of known epitopes. Presented at the 12th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, University of Texas Medical Branch Galveston, Galveston, TX, May 18-19, 2007. R833137 (Final)
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Presentation Identifying conformational epitope of cedar pollen allergen (Jun a 1). None Saito A, Braun BA, Ning B, Midoro-Horiuti T, Goldblum RM Saito A, Braun BA, Ning B, Midoro-Horiuti T, Goldblum RM. Identifying conformational epitope of cedar pollen allergen (Jun a 1). Presented at the Summer Undergraduate Research Program, University of Texas Medical Branch Galveston, Galveston, TX, August 14, 2009. R833137 (Final)
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Presentation Common allergenic epitopes in nut proteins contribute to cross reactivity. None Schein CH Schein CH. Common allergenic epitopes in nut proteins contribute to cross reactivity. Presented at the ILSI Health and Environmental Sciences Institute (HESI) Food Allergy Workshop, The Beacon Hotel and Corporate Quarters, Washington, DC, October 15, 2008. R833137 (Final)
R834066 (2010)
R834066 (Final)
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Presentation Defining IgE epitopes involved in allergen cross reactivity. None Schein CH Schein CH. Defining IgE epitopes involved in allergen cross reactivity. Presented at the UTMB Immunology Research in Progress Seminar, The University of Texas Medical Branch Galveston, Galveston, TX, April 1, 2009. R833137 (Final)
R834066 (2010)
R834066 (Final)
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Presentation Identifying similar IgE-epitopes in peanut and walnut allergens. None Schein CH, Maleki SJ, Teuber S Schein CH, Maleki SJ, Teuber S. Identifying similar IgE-epitopes in peanut and walnut allergens. Presented at the American Academy of Allergy, Asthma & Immunology (AAAAI) Annual Meeting, New Orleans, LA, February 26-March 2, 2010. R833137 (Final)
R834066 (2010)
R834066 (Final)
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Presentation Using physicochemical-property similarity to define common IgE-epitopes in peanut and walnut allergens. None Schein CH, Maleki S, Teuber S Schein CH, Maleki S, Teuber S. Using physicochemical-property similarity to define common IgE-epitopes in peanut and walnut allergens. Presented at the 15th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, Hotel Galvez, Galveston, TX, March 19, 2010. R833137 (Final)
R834066 (2010)
R834066 (Final)
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Presentation Identification of Jun a 1 cross-reactive peptides using physico-chemical indices and partial least squares. None Schein CH, Ivanciuc O, Midoro-Horiuti T, Xie L, Hillman GR, Goldblum RM, Braun W Schein CH, Ivanciuc O, Midoro-Horiuti T, Xie L, Hillman GR, Goldblum RM, Braun W. Identification of Jun a 1 cross-reactive peptides using physico-chemical indices and partial least squares. Presented at the 13th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, University of Texas Medical Branch Galveston, Galveston, TX May 16-17, 2008. R833137 (Final)
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Presentation Mapping conformational epitopes on Jun a 1, the major allergen of mountain cedar pollen. None Tiwari R, Ning B, Negi S, Endsley M, Estes D, Schein C, Braun W, Midoro-Horiuti T, Goldblum R Tiwari R, Ning B, Negi S, Endsley M, Estes D, Schein C, Braun W, Midoro-Horiuti T, Goldblum R. Mapping conformational epitopes on Jun a 1, the major allergen of mountain cedar pollen. Presented at the Annual Meeting of American Academy of Allergy, Asthma and Immunology, San Diego, CA, February 23-27, 2007. R833137 (Final)
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Presentation Mapping conformational epitopes on Jun a 1, the major allergen of mountain cedar pollen. None Tiwari R, Ning B, Negi SS, Endsley M, Estes D, Schein CH, Braun W, Midoro-Horiuti T, Goldblum R Tiwari R, Ning B, Negi SS, Endsley M, Estes D, Schein CH, Braun W, Midoro-Horiuti T, Goldblum R. Mapping conformational epitopes on Jun a 1, the major allergen of mountain cedar pollen. Presented at the 12th Annual Sealy Center for Structural Biology and Molecular Biophysics Symposium, University of Texas Medical Branch Galveston, Galveston, TX, May 18-19, 2007. R833137 (Final)
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Presentation Validation of phage display and computational algorithms for mapping conformational epitopes. None Tiwari R, Negi S, Midoro-Horiuti T, Pomes A, Chapman MD, Braun W, Goldblum RM Tiwari R, Negi S, Midoro-Horiuti T, Pomes A, Chapman MD, Braun W, Goldblum RM. Validation of phage display and computational algorithms for mapping conformational epitopes. Presented at the Annual Meeting of American Academy of Allergy, Asthma and Immunology, Philadelphia, PA, March 14-18, 2008. R833137 (Final)
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Presentation Risk assessment of food allergenicity by a data base approach. None Braun W, Goldblum RM, Schein CH, Midoro-Horiuti T, Gendel S Braun W, Goldblum RM, Schein CH, Midoro-Horiuti T, Gendel S. Risk assessment of food allergenicity by a data base approach. Presented at the Second Symposium for Agricultural Biotechnology Risk Analysis Research organized by the AGRA Task Group, College Park, MD, December 5-6, 2007. R833137 (2008)
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Working Group/Panel FIFRA Scientific Advisory Panel of the U.S. EPA None Braun W Braun W. Participation in the FIFRA Scientific Advisory Panel of the U.S. EPA, EPA Conference Center, Arlington, VA, February 25-27, 2009. R833137 (Final)
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