Grantee Research Project Results
Publications Details for Grant Number R832413C004
Oxidative Stress Responses to PM Exposure in Elderly Individuals With Coronary Heart Disease
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| Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year | Document Sources |
|---|---|---|---|---|---|---|
| Abstract | Associations between personal, indoor, and residential outdoor pollutant concentrations: implications for exposure assessment to size fractionated PM. | EPIDEMIOLOGY | Arhami M, Polidori A, Tjoa T, Delfino RJ, Sioutas C | Arhami M, Polidori A, Tjoa T, Delfino RJ, Sioutas C. Associations between personal, indoor, and residential outdoor pollutant concentrations:implications for exposure assessment to size fractionated PM. Epidemiology 2008;19(6):S82-S83. |
R832413C004 (Final) |
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| Abstract | Organic compound characterization and source apportionment of indoor and outdoor quasi-ultrafine PM in retirement homes of the Los Angeles Basin. | GEOPHYSICAL RESEARCH ABSTRACTS | Arhami M, Minguillon MC, Polidori A, Schauer JJ, Delfino RJ, Sioutas C | Arhami M, Minguillon MC, Polidori A, Schauer JJ, Delfino RJ, Sioutas C. Organic compound characterization and source apportionment of indoor and outdoor quasi-ultrafine PM in retirement homes of the Los Angeles Basin. Geophysical Research Abstracts 2009;11:EGU2009-26074-1. |
R832413C004 (Final) |
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| Abstract | Circulating biomarkers of oxidative stress, inflammation, and thrombosis are associated with urban air pollution in elderly subjects with a history of coronary artery disease. | None | Delfino RJ, Staimer N, Tjoa T, Polidori A, Arhami M, Kleinman MT, Vaziri N, Sioutas C | Delfino RJ, Staimer N, Tjoa T, Polidori A, Arhami M, Kleinman MT, Vaziri N, Sioutas C. Circulating biomarkers of oxidative stress, inflammation, and thrombosis are associated with urban air pollution in elderly subjects with a history of coronary artery disease. In:Proceedings of the American Thoracic Society, 2007;175:A959. |
R832413 (2008) R832413C004 (2008) R832413C004 (2009) R832413C004 (Final) |
not available |
| Abstract | Exhaled NO in elderly subjects with a history of coronary artery disease and urban air pollution. | None | Delfino RJ, Staimer N, Tjoa T, Polidori A, Arhami M, Gillen D, Sioutas C | Delfino RJ, Staimer N, Tjoa T, Polidori A, Arhami M, Gillen D, Sioutas C. Exhaled NO in elderly subjects with a history of coronary artery disease and urban air pollution. In:Proceedings of the American Thoracic Society, 2007;175:A960. |
R832413 (2008) R832413C004 (2008) R832413C004 (2009) R832413C004 (Final) |
not available |
| Abstract | Biomarkers of inflammation and antioxidant activity, and exposure to indoor and outdoor home air pollution in elderly people with coronary artery disease. | EPIDEMIOLOGY | Delfino RJ, Staimer N, Tjoa T, Polidori A, Arhami M, Gillen DL, Sioutas C | Delfino RJ, Staimer N, Tjoa T, Polidori A, Arhami M, Gillen DL, Sioutas C. Biomarkers of inflammation and antioxidant activity, and exposure to indoor and outdoor home air pollution in elderly people with coronary artery disease. Epidemiology 2008;19(6):S353-S354. |
R832413C004 (2009) R832413C004 (Final) |
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| Abstract | Ambulatory blood pressure and traffic-related air pollution:effect modification by physical activity in an elderly panel. | AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | Delfino RJ, Tjoa T, Gillen D, Staimer N, Polidori A, Arhami M, Sioutas C, Longhurst J | Delfino RJ, Tjoa T, Gillen D, Staimer N, Polidori A, Arhami M, Sioutas C, Longhurst J. Ambulatory blood pressure and traffic-related air pollution:effect modification by physical activity in an elderly panel. American Journal of Respiratory and Critical Care Medicine 2009;179:A1172. |
R832413C004 (Final) |
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| Abstract | Ischemic ST segment depression in ambulatory ECGs in relation to hourly exposure to traffic-related air pollution among the elderly. | AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | Delfino RJ, Gillen D, Tjoa T, Staimer N, Arhami M, Polidori A, Sioutas C, Longhurst J | Delfino RJ, Gillen D, Tjoa T, Staimer N, Arhami M, Polidori A, Sioutas C, Longhurst J. Ischemic ST segment depression in ambulatory ECGs in relation to hourly exposure to traffic-related air pollution among the elderly. American Journal of Respiratory and Critical Care Medicine 2010;181:A1708. |
R832413C004 (Final) |
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| Abstract | Systemic and airway biomarkers of inflammation in an elderly panel cohort are related to the potential of airborne particles to generate reactive oxygen species in alveolar macrophage cells in vitro. | AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | Delfino RJ, Gillen D, Tjoa T, Staimer N, Arhami M, Polidori A, George SC, Shafer M, Schauer JJ, Sioutas C | Delfino RJ, Gillen D, Tjoa T, Staimer N, Arhami M, Polidori A, George SC, Shafer M, Schauer JJ, Sioutas C. Systemic and airway biomarkers of inflammation in an elderly panel cohort are related to the potential of airborne particles to generate reactive oxygen species in alveolar macrophage cells in vitro. American Journal of Respiratory and Critical Care Medicine 2010;181:A1715. |
R832413C004 (Final) |
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| Abstract | Associations between source-resolved particulate matter and cardiorespiratory emergency department visits. | EPIDEMIOLOGY | Sarnat JA, Marmur A, Klein M, Kim E, Russell AG, Mulholland JA, Hopke PK, Ebelt Sarnat S, Peel JL, Tolbert PE | Sarnat JA, Marmur A, Klein M, Kim E, Russell AG, Mulholland JA, Hopke PK, Ebelt Sarnat S, Peel JL, Tolbert PE. Associations between source-resolved particulate matter and cardiorespiratory emergency department visits. Epidemiology 2006;17(6):S267-S268. |
R829213 (2006) R829213 (Final) R832413C004 (2009) |
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| Abstract | A new assay to screen for the inhibitory capacity of air pollutant components on antioxidant enzyme activities. | AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | Staimer N, Cho A, Delfino RJ | Staimer N, Cho A, Delfino RJ. A new assay to screen for the inhibitory capacity of air pollutant components on antioxidant enzyme activities. American Journal of Respiratory and Critical Care Medicine 2010;181:A1159. |
R832413C004 (Final) |
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| Journal Article | Associations between personal, indoor, and residential outdoor pollutant concentrations: implications for exposure assessment to size-fractionated particulate matter. | Journal of the Air and Waste Management Association | Arhami M, Polidori A, Delfino RJ, Tjoa T, Sioutas C | Arhami M, Polidori A, Delfino RJ, Tjoa T, Sioutas C. Associations between personal, indoor, and residential outdoor pollutant concentrations:implications for exposure assessment to size-fractionated particulate matter. Journal of the Air & Waste Management Association 2009;59(4):392-404. |
R832413 (2009) R832413 (Final) R832413C001 (2009) R832413C001 (Final) R832413C004 (2009) R832413C004 (2010) R832413C004 (Final) |
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| Journal Article | Organic compound characterization and source apportionment of indoor and outdoor quasi-ultrafine PM in retirement homes of the Los Angeles Basin. | INDOOR AIR | Arhami M, Minguillon MC, Polidori A, Schauer JJ, Delfino RJ, Sioutas C | Arhami M, Minguillon MC, Polidori A, Schauer JJ, Delfino RJ, Sioutas C. Organic compound characterization and source apportionment of indoor and outdoor quasi-ultrafine particulate matter in retirement homes of the Los Angeles Basin. Indoor Air 2010;20(1):17-30. |
R832413 (2009) R832413 (Final) R832413C001 (2009) R832413C001 (Final) R832413C004 (2009) R832413C004 (2010) R832413C004 (Final) |
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| Journal Article | Circulating biomarkers of inflammation, antioxidant activity, and platelet activation are associated with primary combustion aerosols in subjects with coronary artery disease. | ENVIRONMENTAL HEALTH PERSPECTIVES | Delfino RJ, Staimer N, Tjoa T, Polidori A, Arhami M, Gillen DL, Kleinman MT, Vaziri ND, Longhurst J, Zaldivar F, Sioutas C | Delfino RJ, Staimer N, Tjoa T, Polidori A, Arhami M, Gillen DL, Kleinman MT, Vaziri ND, Longhurst J, Zaldivar F, Sioutas C. Circulating biomarkers of inflammation, antioxidant activity, and platelet activation are associated with primary combustion aerosols in subjects with coronary artery disease. Environmental Health Perspectives 2008;116(7):898-906. |
R832413 (2007) R832413 (2008) R832413 (2009) R832413 (Final) R832413C001 (2007) R832413C001 (2008) R832413C001 (Final) R832413C004 (2007) R832413C004 (2008) R832413C004 (2009) R832413C004 (2010) R832413C004 (Final) |
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| Journal Article | Air pollution exposures and circulating biomarkers of effect in a susceptible population: clues to potential causal component mixtures and mechanisms. | ENVIRONMENTAL HEALTH PERSPECTIVES | Delfino RJ, Staimer N, Tjoa T, Gillen D, Polidori A, Arhami M, Kleinman MT, Vaziri ND, Longhurst J, Sioutas C | Delfino RJ, Staimer N, Tjoa T, Gillen DL, Polidori A, Arhami M, Kleinman MT, Vaziri ND, Longhurst J, Sioutas C. Air pollution exposures and circulating biomarkers of effect in a susceptible population: clues to potential causal component mixtures and mechanisms. Environmental Health Perspectives 2009;117(8):1232-1238. |
R832413 (2009) R832413 (Final) R832413C001 (2009) R832413C001 (Final) R832413C004 (2009) R832413C004 (2010) R832413C004 (Final) |
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| Journal Article | Association of biomarkers of systemic inflammation with organic components and source tracers in quasi-ultrafine particles. | None | Delfino RJ, Staimer N, Tjoa T, Arhami M, Polidori A, Gillen DL, Kleinman MT, Schauer JJ, Sioutas C | Delfino RJ, Staimer N, Tjoa T, Arhami M, Polidori A, Gillen DL, Kleinman MT, Schauer JJ, Sioutas C. Association of biomarkers of systemic inflammation with organic components and source tracers in quasi-ultrafine particles. Environmental Health Perspectives 2010;118(6):756-762. |
R832413 (Final) R832413C001 (2010) R832413C001 (Final) R832413C004 (2010) R832413C004 (Final) |
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| Journal Article | Traffic-related air pollution and blood pressure in elderly subjects with coronary artery disease. | EPIDEMIOLOGY | Delfino RJ, Tjoa T, Gillen DL, Staimer N, Polidori A, Arhami M, Jamner L, Sioutas C, Longhurst J | Delfino RJ, Tjoa T, Gillen DL, Staimer N, Polidori A, Arhami M, Jamner L, Sioutas C, Longhurst J. Traffic-related air pollution and blood pressure in elderly subjects with coronary artery disease. Epidemiology 2010;21(3):396-404. |
R832413 (2009) R832413 (Final) R832413C001 (2009) R832413C001 (2010) R832413C001 (Final) R832413C004 (2010) R832413C004 (Final) |
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| Journal Article | Associations of primary and secondary organic aerosols with airway and systemic inflammation in an elderly panel cohort. | None | Delfino RJ, Staimer N, Tjoa T, Arhami M, Polidori A, Gillen DL, George SC, Shafer MM, Schauer JJ, Sioutas C | Delfino RJ, Staimer N, Tjoa T, Arhami M, Polidori A, Gillen DL, George SC, Shafer MM, Schauer JJ, Sioutas C. Associations of primary and secondary organic aerosols with airway and systemic inflammation in an elderly panel cohort. Epidemiology 2010;21(6):892-902. |
R832413 (Final) R832413C001 (2010) R832413C001 (Final) R832413C004 (2010) R832413C004 (Final) |
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| Journal Article | Electrocardiographic ST-segment depression and exposure to traffic-related aerosols in subjects with coronary artery disease. | None | Delfino RJ, Gillen DL, Tjoa T, Staimer N, Polidori A, Arhami M, Sioutas C, Longhurst J | Delfino RJ, Gillen DL, Tjoa T, Staimer N, Polidori A, Arhami M, Sioutas C, Longhurst J. Electrocardiographic ST-segment depression and exposure to traffic-related aerosols in elderly subjects with coronary artery disease. Environmental Health Perspectives 2011;119(2):196-202. |
R832413 (Final) R832413C001 (2010) R832413C001 (Final) R832413C004 (2010) R832413C004 (Final) |
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| Journal Article | Air pollution and circulating biomarkers of oxidative stress. | None | Delfino RJ, Staimer N, Vaziri ND | Delfino RJ, Staimer N, Vaziri ND. Air pollution and circulating biomarkers of oxidative stress. Air Quality, Atmosphere & Health 2011;4(1):37-52. |
R832413 (Final) R832413C004 (2010) R832413C004 (Final) |
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| Journal Article | Determination of metal-based hydroxyl radical generating capacity of ambient and diesel exhaust particles. | INHALATION TOXICOLOGY | DiStefano E, Eiguren-Fernandez A, Delfino RJ, Sioutas C, Froines J, Cho AK | DiStefano E, Eiguren-Fernandez A, Delfino RJ, Sioutas C, Froines JR, Cho AK. Determination of metal-based hydroxyl radical generating capacity of ambient and diesel exhaust particles. Inhalation Toxicology 2009;21(9):731-738. |
R832413 (2009) R832413 (Final) R832413C001 (2009) R832413C001 (Final) R832413C003 (2009) R832413C003 (2010) R832413C004 (2010) |
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| Journal Article | Ethane and n-pentane in exhaled breath are biomarkers of exposure not effect. | BIOMARKERS | Gorham KA, Sulbaek Andersen MP, Meinardi S, Delfino RJ, Staimer N, Tjoa T, Rowland FS, Blake DR | Gorham KA, Sulbaek Andersen MP, Meinardi S, Delfino RJ, Staimer N, Tjoa T, Rowland FS, Blake DR. Ethane and n-pentane in exhaled breath are biomarkers of exposure not effect. Biomarkers 2009;14(1):17-25. |
R832413 (Final) R832413C004 (2009) R832413C004 (2010) R832413C004 (Final) |
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| Journal Article | Relationships between size-fractionated indoor and outdoor trace elements at four retirement communities in southern California. | ATMOSPHERIC CHEMISTRY AND PHYSICS | Polidori A, Cheung KL, Arhami M, Delfino RJ, Schauer JJ, Sioutas C | Polidori A, Cheung KL, Arhami M, Delfino RJ, Schauer JJ, Sioutas C. Relationships between size-fractionated indoor and outdoor trace elements at four retirement communities in southern California. Atmospheric Chemistry and Physics 2009;9(14):4521-4536. |
R832413 (2009) R832413 (Final) R832413C001 (2009) R832413C001 (Final) R832413C004 (2009) R832413C004 (2010) R832413C004 (Final) R833743 (Final) |
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| Journal Article | On the interaction between glyceraldehyde-3-phosphate dehydrogenase and airborne particles: evidence for electrophilic species. | ATMOSPHERIC ENVIRONMENT | Shinyashiki M, Rodriguez CE, Di Stefano EW, Sioutas C, Delfino RJ, Kumagai Y, Froines JR, Cho AK | Shinyashiki M, Rodriguez CE, Di Stefano EW, Sioutas C, Delfino RJ, Kumagai Y, Froines JR, Cho AK. On the interaction between glyceraldehyde-3-phosphate dehydrogenase and airborne particles:evidence for electrophilic species. Atmospheric Environment 2008;42(3):517-529. |
R832413 (2008) R832413 (2009) R832413 (Final) R832413C001 (2008) R832413C001 (Final) R832413C003 (2007) R832413C003 (2008) R832413C003 (2010) R832413C003 (Final) R832413C004 (2009) R832413C004 (2010) |
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| Journal Article | Electrophilic and redox properties of diesel exhaust particles. | ENVIRONMENTAL RESEARCH | Shinyashiki M, Eiguren-Fernandez A, Schmitz DA, Di Stefano E, Li N, Linak WP, Cho SH, Froines JR, Cho AK | Shinyashiki M, Eiguren-Fernandez A, Schmitz DA, Di Stefano E, Li N, Linak WP, Cho S-H, Froines JR, Cho AK. Electrophilic and redox properties of diesel exhaust particles. Environmental Research 2009;109(3):239-244. |
R832413 (2008) R832413 (Final) R832413C003 (2009) R832413C003 (2010) R832413C003 (Final) R832413C004 (2010) |
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| Journal Article | Glutathione peroxidase inhibitory assay for electrophilic pollutants in diesel exhaust and tobacco smoke. | None | Staimer N, Nguyen TB, Nizkorodov SA, Delfino RJ | Staimer N, Nguyen TB, Nizkorodov SA, Delfino RJ. Glutathione peroxidase inhibitory assay for electrophilic pollutants in diesel exhaust and tobacco smoke. Analytical and Bioanalytical Chemistry 2012;403(2):431-441. |
R832413 (Final) R832413C004 (Final) |
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| Presentation | Properties and composition of size fractionated indoor, outdoor, and personal particulate matter in retirement homes of the Los Angeles Basin. | None | Arhami M, Polidori A, Delfino RJ, Sioutas C | Arhami M, Polidori A, Delfino RJ, Sioutas C. Properties and composition of size fractionated indoor, outdoor, and personal particulate matter in retirement homes of the Los Angeles Basin. Presented at the American Geophysical Union Fall Meeting, San Francisco, CA, December 10-14, 2007. |
R832413C004 (2009) R832413C004 (2010) R832413C004 (Final) |
not available |
| Presentation | Associations between personal, indoor, and residential outdoor pollutant concentrations: implications for exposure assessment to size fractionated PM. | None | Arhami M, Polidori A, Tjoa T, Delfino RJ, and Sioutas C | Arhami M, Polidori A, Tjoa T, Delfino RJ, and Sioutas C. Associations between personal, indoor, and residential outdoor pollutant concentrations: implications for exposure assessment to size fractionated PM. Presented at the 2008 Joint Annual Conference of the International Society for Environmental Epidemiology & International Society of Exposure Analysis, Pasadena, CA, October 12-16, 2008. |
R832413C004 (2009) R832413C004 (2010) R832413C004 (Final) |
not available |
| Presentation | Correlations among personal, indoor, and ambient pollutant concentrations: implications for studying exposure to size fractionated PM. | None | Arhami M, Polidori A, Tjoa T, Delfino RJ, Sioutas C | Arhami M, Polidori A, Tjoa T, Delfino RJ, Sioutas C. Correlations among personal, indoor, and ambient pollutant concentrations:implications for studying exposure to size fractionated PM. Presented at the American Association for Aerosol Research 27th Annual Conference, Orlando, FL, October 20-24, 2008. |
R832413C004 (2009) R832413C004 (2010) R832413C004 (Final) |
not available |
| Presentation | Organic compound characterization and source apportionment of indoor and outdoor quasi-ultrafine PM in retirement homes of the Los Angeles Basin. | None | Arhami M, Minguillon MC, Polidori A, Schauer JJ, Delfino RJ, Sioutas C | Arhami M, Minguillon MC, Polidori A, Schauer JJ, Delfino RJ, Sioutas C. Organic compound characterization and source apportionment of indoor and outdoor quasi-ultrafine PM in retirement homes of the Los Angeles Basin. Presented at the European Geosciences Union General Assembly, Vienna, Austria, April 19-24, 2009. |
R832413C004 (2010) R832413C004 (Final) |
not available |
| Presentation | Exhaled NO in elderly subjects with a history of coronary artery disease and urban air pollution. | None | Delfino RJ, Staimer N, Tjoa T, Polidori A, Arhami M, Gillen D, Sioutas C | Delfino RJ, Staimer N, Tjoa T, Polidori A, Arhami M, Gillen D, Sioutas C. Exhaled NO in elderly subjects with a history of coronary artery disease and urban air pollution. Presented at the American Thoracic Society International Conference, San Francisco, CA, May 18-23, 2007. |
R832413C004 (2008) R832413C004 (2009) R832413C004 (2010) R832413C004 (Final) |
not available |
| Presentation | Circulating biomarkers of oxidative stress, inflammation, and thrombosis are associated with urban air pollution in elderly subjects with a history of coronary artery disease. | None | Delfino RJ, Staimer N, Tjoa T, Polidori A, Arhami M, Kleinman MT, Vaziri N, Sioutas C | Delfino RJ, Staimer N, Tjoa T, Polidori A, Arhami M, Kleinman MT, Vaziri N, Sioutas C. Circulating biomarkers of oxidative stress, inflammation, and thrombosis are associated with urban air pollution in elderly subjects with a history of coronary artery disease. Presented at the American Thoracic Society International Conference, San Francisco, CA, May 18-23, 2007. |
R832413C004 (2007) R832413C004 (2008) R832413C004 (2009) R832413C004 (2010) R832413C004 (Final) |
not available |
| Presentation | Biomarkers of inflammation and antioxidant activity, and exposure to indoor and outdoor home air pollution in elderly people with coronary artery disease. | None | Delfino RJ, Staimer N, Tjoa T, Polidori A, Arhami M, Gillen DL, Sioutas C | Delfino RJ, Staimer N, Tjoa T, Polidori A, Arhami M, Gillen DL, Sioutas C. Biomarkers of inflammation and antioxidant activity, and exposure to indoor and outdoor home air pollution in elderly people with coronary artery disease. Presented at the 2008 Joint Annual Conference of the International Society for Environmental Epidemiology & International Society of Exposure Analysis, Pasadena, CA, October 12-16, 2008. |
R832413C004 (2009) R832413C004 (Final) |
not available |
| Presentation | Ambulatory blood pressure and traffic-related air pollution:effect modification by physical activity in an elderly panel. | None | Delfino RJ, Tjoa T, Gillen D, Staimer N, Polidori A, Arhami M, Sioutas C, Longhurst J | Delfino RJ, Tjoa T, Gillen D, Staimer N, Polidori A, Arhami M, Sioutas C, Longhurst J. Ambulatory blood pressure and traffic-related air pollution:effect modification by physical activity in an elderly panel. Presented at the American Thoracic Society, International Conference, San Diego, CA, May 16-20, 2009. |
R832413C004 (2010) R832413C004 (Final) |
not available |
| Presentation | Relationships between indoor and outdoor ambient particulate and gaseous species in two retirement homes: implications for particulate matter exposure. | None | Polidori A, Allen E, Reff A, Arhami M, Delfino RJ, Sioutas C | Polidori A, Allen E, Reff A, Arhami M, Delfino RJ, Sioutas C. Relationships between indoor and outdoor ambient particulate and gaseous species in two retirement homes: implications for particulate matter exposure. Presented at the 8th International Aerosol Conference of the American Association for Aerosol Research, Salzburg, Austria, September 9-14, 2007. |
R832413C004 (2009) R832413C004 (2010) R832413C004 (Final) |
not available |
| Presentation | Real-time characterization of particle-bound polycyclic aromatic hydrocarbons in ambient aerosols and from motor-vehicle exhaust. | None | Polidori A, Hu S, Biswas S, Delfino RJ, Sioutas C | Polidori A, Hu S, Biswas S, Delfino RJ, Sioutas C. Real-time characterization of particle-bound polycyclic aromatic hydrocarbons in ambient aerosols and from motor-vehicle exhaust. Presented at the American Association for Aerosol Research 27th Annual Conference, Orlando, FL, October 20-24, 2008. |
R832413C004 (2009) R832413C004 (2010) R832413C004 (Final) |
not available |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.