Grantee Research Project Results
Publications Details for Grant Number R826652
Modeling Microbial PCB Degradation and Binding
Other Views
- All
Publications - Selected
Publication Types - Journal
Articles - Publications Submitted
After Final Report - Redisplay this page with
Reference Title, Journal, and Author Columns - Display this Page
in RIS Format
| Reference Type | Citation | Progress Report Year | Document Sources |
|---|---|---|---|
| Abstract | Dercova K, Vrana B, Balaz S. A kinetic distribution model of evaporation, biosorption and biodegradation of the polychlorinated biphenyls in the suspension of Pseudomonas stutzeri. In: Book of Abstracts, International Union of Pure and Applied Chemistry International Conference on Degradation Processes in the Environment, Dubrovnik, Croatia, May 24-28, 1998. |
R826652 (Final) |
not available |
| Abstract | Dercova K, Vrana B, Balaz S, Tandlich R. Kinetics of biodegradation of PCBs in the bacterial cell suspension. In: 9th European Congress on Biotechnology: Brussels, Belgium, July 11-15, 1999: Book of Abstracts.Brussels: ECB, 1999. |
R826652 (Final) |
not available |
| Book | Hoeltje H-D, Sippl W, eds. Rational Approaches to Drug Design: Proceedings of the 13th European Symposium on Quantitative Structure-Activity Relationships, Düsseldorf, Germany, August 27-September 1, 2000. Philadelphia, PA: Prous Science, 2001, 536 pp. |
R826652 (Final) |
|
| Book Chapter | Balaz S. Subcellular pharmacokinetics in drug discovery and development. In: Borchardt RT, Freidinger RM, Sawyer TK, Smith PL, eds. Integration of Pharmaceutical Discovery and Development: Case Histories. Pharmaceutical Biotechnology Series, Volume 11, New York: Plenum Press, 1998, pp. 22-27. |
R826652 (2001) R826652 (Final) |
|
| Book Chapter | Balaz S, Hornak V. Multiple binding modes in three-dimensional quantitative structure-activity relationships. In: Walker JD, ed. QSARs for Pollution Prevention, Toxicity Screening, Risk Assessment, and Web Applications. Pensacola, FL: SETAC Press, 2003, Chapter 8, pp. 107-122. |
R826652 (2000) R826652 (Final) |
|
| Book Chapter | Dercova K, Balaz S, Vrana B, Tandlich R. Aerobic biodegradation of polychlorinated biphenyls (PCBs): the fate, distribution, kinetics and enhancement of PCB biodegradation efficacy in the bacterial cell suspension of Pseudomonas stutzeri. In: Sasek V, Glaser JA, Baveye P, eds. The Utilization of Bioremediation to Reduce Soil Contamination:Problems and Solutions. NATO Science Series, Series IV: Earth and Environmental Sciences, Dordrecht, The Netherlands: Kluwer Academic Publishers, 2003, pp. 95-113. |
R826652 (Final) |
|
| Book Chapter | Lukacova V, Balaz S. Incorporation of multiple binding modes into 3D-QSAR methods. In: Hoeltje H-D, Sippl W, eds. Rational Approaches to Drug Design: Proceedings of the 13th European Symposium on Quantitative Structure-Activity Relationships, August 27–September 1, 2000. Philadelphia, PA: Prous Science, 2001, pp. 354-358. |
R826652 (2000) R826652 (Final) |
|
| Book Chapter | Tandlich R, Vrana B, Balaz S. Monitoring of polychlorinated biphenyls in Slovak freshwater sediments:use of semipermeable membrane devices. In: Sasek V, Glaser JA, Baveye P, eds. The Utilization of Bioremediation to Reduce Soil Contamination: Problems and Solutions. NATO Science Series, Series IV: Earth and Environmental Sciences, Dordrecht, The Netherlands: Kluwer Academic Publishers, 2003, pp. 221-228. |
R826652 (2001) R826652 (Final) |
|
| Journal Article | Balaz S, Lukacova V. A model-based dependence of the human tissue/blood partition coefficients of chemicals on lipophilicity and tissue composition. Quantitative Structure-Activity Relationships 1999;18(4):361-368. |
R826652 (1999) R826652 (Final) |
|
| Journal Article | Balaz S. Lipophilicity in trans-bilayer transport and subcellular pharmacokinetics. Perspectives in Drug Discovery and Design 2000;19(1):157-177. |
R826652 (1999) R826652 (Final) |
|
| Journal Article | Balaz S, Lukacova V. Subcellular pharmacokinetics and its potential for library focusing. Journal of Molecular Graphics & Modelling 2002;20(6):479-490. |
R826652 (2001) R826652 (Final) |
|
| Journal Article | Balaz S. Subcellular pharmacokinetics: one-compartment model. American Journal of Pharmaceutical Education 2002;66(1):66-71. |
R826652 (Final) |
|
| Journal Article | Dercova K, Vrana B, Balaz S. Evaporation and elimination of PCBs during degradation by Pseudomonas stutzeri. Toxicological and Environmental Chemistry 1998;66(1-4):11-16. |
R826652 (Final) |
|
| Journal Article | Dercova K, Vrana B, Balaz S. A Kinetic distribution model of evaporation, biosorption and biodegradation of polychlorinated biphenyls (PCBs) in the suspension of Pseudomonas stutzeri. Chemosphere 1999;38(6):1391-1400. |
R826652 (1999) R826652 (Final) |
|
| Journal Article | Hornak V, Balaz S, Majekova M. Binding modes of PCBs to a degrading enzyme: a receptor-mapping study. General Physiology and Biophysics 1998;17(2):105-116. |
R826652 (Final) |
|
| Journal Article | Hornak V, Balaz S, Schaper K-J, Seydel JK. Multiple binding modes in 3D-QSAR: microbial degradation of polychlorinated biphenyls. Quantitative Structure-Activity Relationships 1998;17(5):427-436. |
R826652 (Final) |
|
| Journal Article | Lukacova V, Balaz S. Multimode ligand binding in receptor site modeling: implementation in CoMFA. Journal of Chemical Information and Computer Science 2003;43(6):2093-2105. |
R826652 (Final) |
|
| Journal Article | Vrana B, Tandlich R, Balaz S, Dercova K. Biosorption of hydrophobic organic pollutants. Chemicke Listy 1998;92(3):186-196. |
R826652 (Final) |
|
| Journal Article | Vrana B, Tandlich R, Balaz S, Dercova K. Aerobic biodegradation of polychlorinated biphenyls by bacteria. Biologia 1998;53(3):251-266. |
R826652 (Final) |
|
| Journal Article | Vrana B, Balaz S, Dercova K, Tandlich R. A kinetic distribution model of evaporation, biosorption and biodegradation of polychlorinated biphenyls (PCBs) in the suspension of Pseudomonas stutzeri. Chemosphere 1999;38(6):1391-1400 |
R826652 (1999) |
|
| Meeting | Balaz S, Lukacova V. Multiple binding modes in CoMFA. In: Book of Abstracts for the 221st American Chemical Society (ACS) Meeting, San Diego, CA, April 1-5, 2001, CINF 0043. |
R826652 (2001) |
not available |
| Patent/Patent Application | Balaz S, Lukacova V. Method for drug design using comparative molecular field analysis (CoMFA) extended for multi-mode/multi-species ligand binding and disposition. U.S. Patent Application, No. 20030148386, August 7, 2003. |
R826652 (2001) R826652 (Final) |
|
| Presentation | Balaz S., Vrana B., Hornak V., Dercova K. Modeling of PCB degradation: Evaporation, distribution, and mapping of the first oxygenase binding site. 19th Annual Meeting of Society for Environmental Toxicology and Chemistry: The Natural Connection: Environmental Integrity and Human Health, Charlotte, NC, November 15-19, 1998. |
R826652 (1998) R826652 (Final) |
not available |
| Presentation | Balaz S, Hornak V. Multiple binding modes in three-dimensional quantitative structure-activity relationships. QSARs to predict endocrine disruption and environmental/health effects. Presented at the 8th International Workshop on Quantitative Structure Activity Relationship in Environmental Sciences, Society for Environmental Toxicology and Chemistry, Baltimore, MD, May 19-20, 1998. |
R826652 (Final) |
not available |
| Presentation | Balaz S, Lukacova V. CoMFA for multiple binding modes: binding of polychlorinated dibenzofurans to Ah receptor. Presented at the Gordon Conference on Quantitative Structure Activity Relationship, Tilton, NH, July 25-30, 1999. |
R826652 (Final) |
not available |
| Presentation | Balaz S, Lukacova V. Multiple binding modes in 3D-QSAR. Presented at the European Conference on QSAR, Duesseldorf, Germany, August 27-September 1, 2000. |
R826652 (2000) R826652 (Final) |
not available |
| Presentation | Balaz S, Lukacova V. Extensions of 3D-QSAR methods. Presented at the 32nd Great Lakes Regional Meeting of the American Chemical Society, Fargo, ND, June 4-6, 2000. |
R826652 (2000) R826652 (Final) |
not available |
| Presentation | Balaz S, Lukacova V. Multiple binding modes in CoMFA. Presented at the 221st American Chemical Society (ACS) Meeting, San Diego, CA, April 1-5, 2001. |
R826652 (2001) R826652 (Final) |
not available |
| Presentation | Balaz S, Lukacova V. Multiple binding modes in 3D-QSAR methods. Presented at The Gordon Conference on Quantitative Structure Activity Relationship, Tilton, NH, August 5, 2001. |
R826652 (Final) |
not available |
| Presentation | Balaz S, Lukacova V. Multiple binding modes in 3D-QSAR. Presented at the 6th World Congress of Theoretically Oriented Chemists, Lugano, Switzerland, August 4-9, 2002. |
R826652 (Final) |
not available |
| Presentation | Dercova K, Vrana B, Balaz S. A kinetic distribution model of evaporation, biosorption and biodegradation of the polychlorinated biphenyls in the suspension of Pseudomonas stutzeri. Presented at the International Union of Pure and Applied Chemistry Conference on Degradation Processes in the Environment, Dubrovnik, Croatia, May 24-28, 1998. |
R826652 (Final) |
not available |
| Presentation | Dercova K, Tandlich R, Brezna B. Biodegradation of PCBs and induction of their cometabolism. Presented at the 10th European Congress on Biotechnology, Madrid, Spain, July 8-11, 2001. |
R826652 (Final) |
not available |
| Presentation | Grabher N, Lukacova V, Balaz S. Determination of amphiphilicity as a factor in trans-bilayer transport. Presented at the 225th National American Chemical Society Meeting, New Orleans, LA, March 23-27, 2003. |
R826652 (Final) |
not available |
| Presentation | Khandelwal A, Lukacova V, Balaz S. Multi-mode binding in the force-field-based 3D-QSAR. Presented at the Gordon Conference on Computer Aided Drug Design, Tilton, NH, July 20-25, 2003. |
R826652 (Final) |
not available |
| Presentation | Lukacova V, Balaz S. Mapping ligand binding sites on macromolecules: PCDF binding to the Ah receptor. Presented at the Joint Conference of South Dakota and North Dakota EPSCoR, Fargo, ND, September 9-10, 1999, p. 82. |
R826652 (1999) |
not available |
| Presentation | Tandlich R, Vrana B, Balaz S. Passive sampler devices and PCB contamination in Slovak fresh water sediments. Presented at the 32nd Great Lakes Regional Meeting of the American Chemical Society, Fargo, ND, June 4-6, 2000. |
R826652 (Final) |
not available |
| Presentation | Tandlich R, Balaz S. Biphenyl behavior in n-octanol/water system. Presented at the 223rd American Chemical Society Meeting, Orlando, FL, April 7-11, 2002. |
R826652 (Final) |
not available |
| Presentation | Tandlich R, Balaz S. Nature of interaction of highly hydrophobic organic compounds with clay minerals. Presented at the 4th Annual Conference on Active Research by Environmental Science Students, Weizmann Institute of Science, Rehovot, Israel, June 11, 2003. |
R826652 (Final) |
not available |
| Proceedings | Dercova K,Vrana B, Balaz S, Tandlich R. Biodegradation of PCBs:distribution model, kinetics and enhancement of efficacy. In:Hartmans S, Lens P, eds. Proceedings of the 4th International Symposium on Environmental Biotechnology: 106th event of the European federation of biotechnology, Noordwijkerhout, The Netherlands, April 10-12, 2000, pp. 349-351. |
R826652 (2001) R826652 (Final) |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.