Grantee Research Project Results
Journal Publications Details for Grant Number R832139C003
Mechanisms of Particulate-Induced Allergic Asthma
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Centers for Children's Environmental Health and Disease Prevention Research (2003)
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Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year | Document Sources |
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Journal Article | A novel promoter polymorphism in the gene encoding complement component 5 receptor 1 on chromosome 19q13.3 is not associated with asthma and atopy in three independent populations. | CLINICAL AND EXPERIMENTAL ALLERGY | Barnes KC, Caraballo L, Munoz M, Zambelli-Weiner A, Ehrlich E, Burki M, Jimenez S, Mathias RA, Stockton ML, Deindl P, Mendoza L, Hershey GK, Nickel R, Wills-Karp M | Barnes KC, Caraballo L, Munoz M, Zambelli-Weiner A, Ehrlich E, Burki M, Jimenez S, Mathias RA, Stockton ML, Deindl P, Mendoza L, Hershey GK, Nickel R, Wills-Karp M. A novel promoter polymorphism in the gene encoding complement component 5 receptor 1 on chromosome 19q13.3 is not associated with asthma and atopy in three independent populations. Clinical and Experimental Allergy 2004;34(5):736-744. |
R832139 (2004) R832139 (2005) R832139 (2007) R832139C003 (2004) |
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Journal Article | Home environmental intervention in inner-city asthma: a randomized controlled clinical trial. | ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY | Eggleston PA, Butz A, Rand C, Curtin-Brosnan J, Kanchanaraksa S, Swartz L, Breysse P, Buckley T, Diette G, Merriman B, Krishnan JA | Eggleston PA, Butz A, Rand C, Curtin-Brosnan J, Kanchanaraksa S, Swartz L, Breysse P, Buckley T, Diette G, Merriman B, Krishnan JA. Home environmental intervention in inner-city asthma:a randomized controlled clinical trial. Annals of Allergy, Asthma & Immunology 2005;95(6):518-524. |
R832139 (2004) R832139 (2005) R832139 (2006) R832139 (2007) R832139 (Final) R832139C001 (2006) R832139C002 (2005) R832139C002 (2006) R832139C003 (2005) |
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Journal Article | Improving indoor environments: reducing allergen exposures. | JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | Eggleston PA | Eggleston PA. Improving indoor environments: reducing allergen exposures. Journal of Allergy and Clinical Immunology 2005;116(1):122-126. |
R832139 (2004) R832139 (2005) R832139 (2006) R832139 (2007) R832139C002 (2005) R832139C003 (2005) |
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Journal Article | Lessons learned for the study of childhood asthma from the Centers for Children’s Environmental Health and Disease Prevention Research. | ENVIRONMENTAL HEALTH PERSPECTIVES | Eggleston PA, Diette G, Lipsett M, Lewis T, Tager I, McConnell R, Chrischilles E, Lanphear B, Miller R, Krishnan J | Eggleston PA, Diette G, Lipsett M, Lewis T, Tager I, McConnell R, Chrischilles E, Lanphear B, Miller R, Krishnan J. Lessons learned for the study of childhood asthma from the Centers for Children’s Environmental Health and Disease Prevention Research. Environmental Health Perspectives 2005;113(10):1430-1436. |
R826710 (Final) R827027 (2002) R829389 (2003) R829389 (2004) R829389 (2005) R829389 (Final) R831710 (2004) R831710 (2005) R831710 (Final) R831861 (2005) R831861 (2006) R831861C001 (2006) R832139 (2004) R832139 (2005) R832139 (2006) R832139C002 (2005) R832139C003 (2005) R832141 (2006) R832141 (2007) R832141 (Final) |
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Journal Article | Altered gene expression profiles in nasal respiratory epithelium reflect stable versus acute childhood asthma. | JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | Guajardo JR, Schleifer KW, Daines MO, Ruddy RM, Aronow BJ, Wills-Karp M, Hershey GK | Guajardo JR, Schleifer KW, Daines MO, Ruddy RM, Aronow BJ, Wills-Karp M, Hershey GK. Altered gene expression profiles in nasal respiratory epithelium reflect stable versus acute childhood asthma. Journal of Allergy and Clinical Immunology 2005;115(2):243-251. |
R832139 (2007) R832139C003 (2006) |
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Journal Article | The anaphylatoxins bridge innate and adaptive immune responses in allergic asthma. | MOLECULAR IMMUNOLOGY | Hawlisch H, Wills-Karp M, Karp CL, Kohl J | Hawlisch H, Wills-Karp M, Karp CL, Kohl J. The anaphylatoxins bridge innate and adaptive immune responses in allergic asthma. Molecular Immunology 2004;41(2-3):123-131. |
R832139 (2004) R832139 (2005) R832139 (2007) R832139C003 (2004) |
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Journal Article | A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma. | JOURNAL OF CLINICAL INVESTIGATION | Kohl J, Baelder R, Lewkowich IP, Pandey MK, Hawlisch H, Wang L, Best J, Herman NS, Sproles AA, Zwirner J, Whitsett JA, Gerard C, Sfyroera G, Lambris JD, Wills-Karp M | Kohl J, Baelder R, Lewkowich IP, Pandey MK, Hawlisch H, Wang L, Best J, Herman NS, Sproles AA, Zwirner J, Whitsett JA, Gerard C, Sfyroera G, Lambris JD, Wills-Karp M. A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma. Journal of Clinical Investigation 2006;116(3):783-796. |
R832139 (2007) R832139C003 (2006) R832139C003 (2007) |
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Journal Article | Complement regulates inhalation tolerance at the dendritic cell/T cell interface. | MOLECULAR IMMUNOLOGY | Kohl J, Wills-Karp M | Kohl J, Wills-Karp M. Complement regulates inhalation tolerance at the dendritic cell/T cell interface. Molecular Immunology 2007;44(1-3):44-56. |
R832139 (Final) R832139C003 (2007) |
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Journal Article | A dual role for complement in allergic asthma. | CURRENT OPINION IN PHARMACOLOGY | Kohl J, Wills-Karp M | Kohl J, Wills-Karp M. A dual role for complement in allergic asthma. Current Opinion in Pharmacology 2007;7(3):283-289. |
R832139 (Final) R832139C003 (2007) |
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Journal Article | CD4+CD25+ T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function. | JOURNAL OF EXPERIMENTAL MEDICINE | Lewkowich IP, Herman NS, Schleifer KW, Dance MP, Chen BL, Dienger KM, Sproles AA, Shah JS, Kohl J, Belkaid Y, Wills-Karp M | Lewkowich IP, Herman NS, Schleifer KW, Dance MP, Chen BL, Dienger KM, Sproles AA, Shah JS, Kohl J, Belkaid Y, Wills-Karp M. CD4+CD25+ T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function. Journal of Experimental Medicine 2005;202(11):1549-1561. |
R832139 (2006) R832139 (2007) R832139C003 (2006) |
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Journal Article | Adult asthma severity in individuals with a history of childhood asthma. | JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | Limb SL, Brown KC, Wood RA, Wise RA, Eggleston PA, Tonascia J, Hamilton RG, Adkinson Jr NF | Limb SL, Brown KC, Wood RA, Wise RA, Eggleston PA, Tonascia J, Hamilton RG, Adkinson Jr NF. Adult asthma severity in individuals with a history of childhood asthma. Journal of Allergy and Clinical Immunology 2005;115(1):61-66. |
R832139 (2004) R832139 (2005) R832139 (2006) R832139 (2007) R832139C002 (2005) R832139C003 (2005) |
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Journal Article | Airborne mouse allergen in the homes of inner-city children with asthma. | JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | Matsui EC, Simons E, Rand C, Butz A, Buckley TJ, Breysse P, Eggleston PA | Matsui EC, Simons E, Rand C, Butz A, Buckley TJ, Breysse P, Eggleston PA. Airborne mouse allergen in the homes of inner-city children with asthma. Journal of Allergy and Clinical Immunology 2005;115(2):358-363. |
R832139 (2004) R832139 (2005) R832139 (2006) R832139 (2007) R832139C002 (2005) R832139C003 (2005) |
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Journal Article | IL-4 induces IL-13-independent allergic airway inflammation. | JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | Perkins C, Wills-Karp M, Finkelman FD | Perkins C, Wills-Karp M, Finkelman FD. IL-4 induces IL-13-independent allergic airway inflammation. Journal of Allergy and Clinical Immunology 2006;118(2):410-419. |
R832139 (Final) R832139C003 (2007) |
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Journal Article | Particulate matter-induced airway hyperresponsiveness is lymphocyte dependent. | ENVIRONMENTAL HEALTH PERSPECTIVES | Saunders V, Breysse P, Clark J, Sproles A, Davila M, Wills-Karp M | Saunders V, Breysse P, Clark J, Sproles A, Davila M, Wills-Karp M. Particulate matter-induced airway hyperresponsiveness is lymphocyte dependent. Environmental Health Perspectives 2010;118(5):640-646. |
R832139 (Final) R832139C003 (Final) |
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Journal Article | Time to draw breath: asthma-susceptibility genes are identified. | NATURE REVIEWS GENETICS | Wills-Karp M, Ewart SL | Wills-Karp M, Ewart SL. Time to draw breath: asthma-susceptibility genes are identified. Nature Reviews Genetics 2004;5(5):376-387. |
R832139 (2004) R832139 (2005) R832139C003 (2004) |
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Journal Article | New insights into the role of the complement pathway in allergy and asthma. | CURRENT ALLERGY AND ASTHMA REPORTS | Wills-Karp M, Koehl J | Wills-Karp M, Koehl J. New insights into the role of the complement pathway in allergy and asthma. Current Allergy and Asthma Reports 2005;5(5):362-369. |
R832139 (2007) R832139C003 (2006) |
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Journal Article | Complement activation pathways: a bridge between innate and adaptive immune responses in asthma. | PROCEEDINGS OF THE AMERICAN THORACIC SOCIETY | Wills-Karp M | Wills-Karp M. Complement activation pathways: a bridge between innate and adaptive immune responses in asthma. Proceedings of the American Thoracic Society 2007;4:247-251. |
R832139C003 (2007) |
not available |
Journal Article | How exposures to biologics influence the induction and incidence of asthma. | ENVIRONMENTAL HEALTH PERSPECTIVES | Zeldin DC, Eggleston P, Chapman M, Piedimonte G, Renz H, Peden D | Zeldin DC, Eggleston P, Chapman M, Piedimonte G, Renz H, Peden D. How exposures to biologics influence the induction and incidence of asthma. Environmental Health Perspectives 2006;114(4):620-626. |
R832139 (2004) R832139 (2005) R832139 (2006) R832139 (2007) R832139C001 (2007) R832139C002 (2005) R832139C003 (2005) |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.