Grantee Research Project Results
Journal Publications Details for Grant Number R823889
Cultured Fish Cells as Model System for Studying Mechanisms of Dioxin Toxicity
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Reference Type | Citation | Progress Report Year | Document Sources |
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Journal Article | Bello SM, Franks DG, Stegeman JJ, Hahn ME. Acquired resistance to Ah receptor agonists in a population of Atlantic kill fish (Fundulus heteroclitus) inhabiting a marine superfund site: in vivo and in vitro studies on the inducibility of xenobiotic metabolizing enzymes. Toxicological Sciences 2001;60(1):77-91. |
R823889 (Final) |
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Journal Article | Celander M, Hahn ME, Stegeman JJ. Cytochromes P450 (CYP) in the Poeciliopsis lucida hepatocellular carcinoma cell line (PLHC-1): dose-and time-dependent glucocorticoid potentiation of CYP1A induction without induction of CYP3A. Archives of Biochemistry and Biophysics 1996;329(1):113-122. |
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Journal Article | Celander M, Bremer J, Hahn ME, Stegeman JJ. Glucocorticoid-xenobiotic interactions: dexamethasone-mediated potentiation of cytochrome P4501A induction by β-naphthoflavone in a fish hepatoma cell line (PLHC-1). Environmental Toxicology and Chemistry 1997;16(5):900-907. |
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Journal Article | Cornell NW, Hahn ME, Martin HA. Characterization and use of isolated toadfish hepatocytes for studies of heme synthesis and utilization. The Biological Bulletin 1995;189(2):227-228. |
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Journal Article | Hahn ME, Woodward BL, Stegeman JJ, Kennedy SW. Rapid assessment of induced cytochrome P4501A protein and catalytic activity in fish hepatoma cells grown in multi-well plates:response to TCDD, TCDF, and two planar PCBs. Environmental Toxicology and Chemistry 1996;15(4):582-591. |
R823889 (Final) |
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Journal Article | Hahn ME, Chandran K. Uroporphyrin accumulation associated with cytochrome P4501A induction in fish hepatoma cells exposed to aryl hydrocarbon receptor agonists, including 2,3,7,8-tetrachlorodibenzo-p-dioxin and planar chlorobiphenyls. Archives of Biochemistry and Biophysics 1996;329(2):163-174. |
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Journal Article | Hahn ME. Biomarkers and bioassays for detecting dioxin-like compounds in the marine environment. Science of the Total Environment 2002;289(1-3):49-69. |
R823889 (Final) |
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Journal Article | Hestermann EV, Stegeman JJ, Hahn ME. Serum alters the uptake and relative potencies of halogenated aromatic hydrocarbons in cell culture bioassays. Toxicological Sciences 2000;53(2):316-325. |
R823889 (Final) |
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Journal Article | Kennedy SW, Lorenzen A, Jones SP, Hahn ME, Stegeman JJ. Cytochrome P4501A induction in avian hepatocyte cultures: a promising approach for predicting the sensitivity of avian species to toxic effects of halogenated aromatic hydrocarbons. Toxicology and Applied Pharmacology 1996;141(1):214-230. |
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Journal Article | Lorenzen A, Kennedy SW, Bastien LJ, Hahn ME. Halogenated aromatic hydrocarbon-mediated porphyrin accumulation and induction of cytochrome P4501A in chicken embryo hepatocytes. Biochemical Pharmacology 1997;53(3):373-384. |
R823889 (Final) |
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Journal Article | Schlezinger JJ, Keller J, Verbrugge LA, Stegeman JJ. 3,3',4,4'-tetrachlorobiphenyl oxidation in fish, bird and reptile species: relationship to cytochrome P450 1A inactivation and reactive oxygen production. Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology 2000;125(3):273-286. |
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Journal Article | White RD, Shea D, Stegeman JJ. Metabolism of the aryl hydrocarbon receptor agonist 3,3',4,4'-tetrachlorobiphenyl by the marine fish scup (Stenotomus chrysops) in vivo and in vitro. Drug Metabolism and Disposition 1997;25(5):564-572. |
R823889 (Final) R827102 (Final) |
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