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Grantee Research Project Results

Journal Publications Details for Grant Number R826132

Models Assessing Direct Effects of Dioxins and Related Compounds on the Ovary

RFA: Endocrine Disruptors (1997)

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Journal Article (6)
Reference Type Citation Progress Report Year Document Sources
Journal Article Gao X, Son DS, Terranova PF, Rozman KK. Toxic equivalency factors of polychlorinated dibenzo-p-dioxins in an ovulation model: validation of the toxic equivalency concept for one aspect of endocrine disruption. Toxicology and Applied Pharmacology 1999;157(2):107-116. R826132 (1999)
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Journal Article Gao X, Terranova PF, Rozman KK. Effects of polychlorinated dibenzofurans, biphenyls, and their mixture with dibenzo-p-dioxins on ovulation in the gonadotropin-primed immature rat: support for the toxic equivalency concept. Toxicology and Applied Pharmacology 2000;163(2):115-124. R826132 (1999)
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Journal Article Gao X, Petroff BK, Rozman KK, Terranova PF. Gonadotropin-releasing hormone (GnRH) partially reverses the inhibitory effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on ovulation in the immature gonadotropin-treated rat. Toxicology 2000;147(1):15-22. R826132 (1999)
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Journal Article Petroff BK, Gao X, Rozman KK, Terranova, PF. Interaction of estradiol and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in an ovulation model: evidence for systemic potentiation and local ovarian effects. Reproductive Toxicology 2000;14(3):247-255. R826132 (1999)
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Journal Article Petroff BK, Gao X, Ohshima KI, Shi FX, Son DS, Roby KF, Rozman KK, Watanabe G, Taya K, Terranova PF. Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on serum inhibin concentrations and inhibin immunostaining during follicular development in female Sprague-Dawley rats. Reproductive Toxicology 2002;16(2):97-105. R826132 (1999)
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Journal Article Son DS, Ushinohama K, Gao X, Taylor CC, Roby KF, Rozman KK, Terranova PF. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) blocks ovulation by a direct action on the ovary without alteration of ovarian steroidogenesis: lack of a direct effect on ovarian granulosa and thecal-interstitial cell steroidogenesis in vitro. Reproductive Toxicology 1999;13(6):521-530. R826132 (1999)
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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Last updated April 28, 2023
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