Grantee Research Project Results
2011 Progress Report: Children's Environmental Health and Disease Prevention Research Centers: Formative Centers
EPA Grant Number: R834678Center: Center for Integrative Research on Childhood Leukemia and the Environment - 2015
Center Director: Metayer, Catherine
Title: Children's Environmental Health and Disease Prevention Research Centers: Formative Centers
Investigators: Woodruff, Tracey J. , Fisher, Susan J. , Steinauer, Jody , McMaster, Michael , Stotland, Naomi
Current Investigators: Woodruff, Tracey J. , Fisher, Susan J. , McMaster, Michael , Stotland, Naomi , Sutton, Patrice , Gerona, Roy
Institution: University of California - San Francisco
EPA Project Officer: Hahn, Intaek
Project Period: May 5, 2010 through May 4, 2014
Project Period Covered by this Report: May 5, 2011 through May 4,2012
Project Amount: $762,983
RFA: Children's Environmental Health and Disease Prevention Research Centers: Formative Centers (with NIEHS) (2009) RFA Text | Recipients Lists
Research Category: Children's Health , Human Health
Objective:
- Communicate the meaning of the Pregnancy Exposure to Environmental Contaminants (PEEC) Formative Centers research broadly.
- Create and disseminate a science-based foundation for clinical care and policy change endorsed by key leaders.
- Sustain and expand a collaborative network of partners.
- Advance public policy in the field of reproductive environmental health.
Progress Summary:
- Hired Jessica Trowbridge at 100 percent to advance our COTC's communication strategy and other COTC activities (June 2011).
- Strengthened our network of collaborators, including convening two meetings of PRHE's From Advancing Science to Ensuring Prevention (FASTEP) Advisory Council (September 2011 and February 2012).
- Developed and implemented a communication strategy to effectively translate the meaning of the science broadly. To this end, we were covered in 45 media stories, including in the San Francisco Chronicle, USA Today online, LA Times, and interviews by KCBS and KCBS Radio; redesigned our website to include better graphics, compatibility with mobile devices, and integration and usability for our collaborators; published four blogs about our scientists, research and related topics in Mission Local, a local online and print newspaper for the San Francisco Mission District; contributed to NIEHS news article "Advising Parents in the Face of Scientific Uncertainty: An Environmental Health Dilemma"; and regularly posted on Twitter and Facebook.
- Advanced the development of a novel methodology to translate the science linking the environment and health in clinical and policy spheres. We published the methodology, the Navigation Guide, in Health Affairs; convened the inaugural meeting of the Navigation Guide Working Group (March 2012); in collaboration with the U.S. Environmental Protection Agency (EPA), initiated the application of the Navigation Guide methodology on a case study of the relationship between exposure to perfluorinated octanoic acid and birth weight; and made numerous presentations to advance the methodology among decision makers in clinical and policy spheres.
- Produced and distributed a wide range of educational materials to support the integration of the science in clinical spheres, including five patient-centered brochures co-branded with FASTEP and other collaborators: Toxic Matters (low-literacy versions in English and Spanish), Pesticides Matter, Work Matters, and Food Matters; produced and distributed Pesticides Matter: A Primer for Reproductive Health Professionals.
- Worked to integrate the science into the purview and activities of the American Congress of Obstetricians & Gynecologists (ACOG) and other health professional societies and institutions. PRHE served as a member of ACOG District IX's (California) legislative committee and as science advisors on reproductive environmental health issues to ACOG District IX and national ACOG; PRHE helped to bring together ACOG and EPA leadership, who in turn identified potential areas of future collaboration; through a mixed methods approach, we gathered the first empirical evidence of knowledge, attitudes and practices related to environmental health among practicing obstetricians in the United States; PRHE served as a member of the California Preconception Care Council; we compiled and disseminated a searchable database of policy statements from health professional organizations related to environmental health: http://prhe.ucsf.edu/prhe/pdfs/Professional%20Statements%20Database.pdf; attended ACOGs national meeting (May 2012); and as listed below, we disseminated the science to health professionals through Grand Rounds and other presentations and publications.
- Collaborated on national efforts to strengthen and build a bridge between the Pediatric Environmental Health Specialty Units (PEHSUs) and obstetricians and their professional organizations in order to ensure a strong referral network for practicing obstetricians who identify a hazardous environmental or occupational exposure.
Future Activities:
Journal Articles: 11 Displayed | Download in RIS Format
Other center views: | All 73 publications | 15 publications in selected types | All 11 journal articles |
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Type | Citation | ||
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Gerona RR, Woodruff TJ, Dickenson CA, Pan J, Schwartz JM, Sen S, Friesen MW, Fujimoto VY, Hunt PA. Bisphenol-A (BPA), BPA glucuronide, and BPA sulfate in midgestation umbilical cord serum in a northern and central California population. Environmental Science & Technology 2013;47(21):12477-12485. |
R834678C001 (Final) R834678C003 (Final) |
Exit |
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Robinson J, Hamilton E, Lam J, Chen H, Woodruff T. Differences in cytochrome p450 enzyme expression and activity in fetal and adult tissues. PLACENTA 2020;100:35-44. |
R834678 (Final) R835433 (Final) |
Exit Exit |
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Sutton P, Giudice LC, Woodruff TJ. Reproductive environmental health. Current Opinion in Obstetrics and Gynecology 2010;22(6):517-524. |
R834678 (2012) |
Exit |
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Sutton P, Woodruff TJ, Vogel S, Bero LA. Conrad and Becker's "10 Criteria" fall short of addressing conflicts of interest in chemical safety studies. Environmental Health Perspectives 2011;119(12):A506-507. |
R834678 (2010) R834678 (2011) |
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Sutton P, Wallinga D, Perron J, Gottlieb M, Sayre L, Woodruff T. Reproductive health and the industrialized food system: a point of intervention for health policy. Health Affairs 2011;30(5):888-897. |
R834678 (2010) R834678 (2011) R834678 (2012) |
Exit Exit Exit |
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Sutton P, Woodruff TJ, Conry J, Giudice LC. Toxic matters and fertility: what can a doctor do? San Francisco Medicine: Journal of the San Francisco Medical Society 2012;85(5)20-22. |
R834678 (2012) |
Exit |
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Sutton P, Woodruff TJ, Perron J, Stotland N, Conry JA, Miller MD, Giudice LC. Toxic environmental chemicals: the role of reproductive health professionals in preventing harmful exposures. American Journal of Obstetrics and Gynecology 2012;207(3)164-173. |
R834678 (2010) R834678 (2011) R834678 (2012) |
Exit Exit |
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Sutton P, Woodruff TJ. Risk communication and decision tools for children's health protection. Birth Defects Research Part C: Embryo Today: Reviews 2013;99(1):45-49. |
R834678 (2012) |
Exit Exit |
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Vandenberg LN, Gerona RR, Kannan K, Taylor JA, van Breemen RB, Dickenson CA, Liao C, Yuan Y, Newbold RR, Padmanabhan V, vom Saal FS, Woodruff TJ. A round robin approach to the analysis of bisphenol A (BPA) in human blood samples. Environmental Health 2014;13(1):25 (20 pp.). |
R834678C001 (Final) R835436 (2014) R835436 (2015) R835436 (2017) |
Exit Exit |
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Woodruff TJ, Sutton P, Navigation Guide Work Group. An evidence-based medicine methodology to bridge the gap between clinical and environmental health sciences. Health Affairs 2011;30(5):931-937. |
R834678 (2010) R834678 (2011) R834678 (2012) |
Exit Exit Exit |
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Woodruff TJ, Burke TA, Zeise L. The need for better public health decisions on chemicals released into our environment. Health Affairs 2011;30(5):957-967. |
R834678 (2011) |
Exit Exit Exit |
Supplemental Keywords:
Risk assessment, metabolism, bioavailability, ethnic groups, endocrine disruptors, sensitive populations, decision making, measurement methods, RFA, Health, Scientific Discipline, Health Risk Assessment, Biochemistry, Children's Health, Biology, prenatal exposure, biological response, assessment of exposureRelevant Websites:
Advising Parents in the Face of Scientific Uncertainty: An Environmental Health Dilemma
MissionLocal - Clinic Exit Exit
An Ecological Approach to Healthy Aging Across the Lifespan Exit Exit
Navigating the Science: Evaluating Research Quality Exit Exit
Progress and Final Reports:
Original Abstract Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
R834678C001 Assessing Maternal and Fetal Exposure to Chemicals
R834678C002 Assessing the Effects of BPA Exposure on Early Human Development
R834678C003 (Pilot Study): Predictors of Maternal Exposure to BPA During Pregnancy
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.