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Grantee Research Project Results

Publications submitted after final report Details for Grant Number R835612

Toxicogenetics of tetrachloroethylene metabolism and toxicity: Using Collaborative Cross mouse population approach to address remaining gaps in human health assessments

RFA: Susceptibility and Variability in Human Response to Chemical Exposure (2013)

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Journal Article (5)
Reference Type Citation Progress Report Year (Date Added to Report) Document Sources
Journal Article Cichocki JA, Luo YS, Furuya S, Venkatratnam A, Konganti K, Chiu, WA, Threadgill DW, Pogribny IP. Modulation of Tetrachloroethylene-Associated Kidney Effects by Nonalcoholic Fatty Liver or Steatohepatitis in Male C57BL/6J Mice. Toxicological Sciences 2019;167(1):126-137. R835612 (Final) (04/30/19)
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Journal Article Dalaijamts C, Cichocki J, Luo Y, Rusyn I, Chiu W. PBPK modeling of impact of nonalcoholic fatty liver disease on toxicokinetics of perchloroethylene in mice. Toxicology and Applied Pharmacology 2020;400(115069). R835612 (Final) (07/17/20)
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Journal Article Ferguson KC, Luo YS, Rusyn I, Chiu WA. Comparative analysis of Rapid Equilibrium Dialysis (RED) and solid phase micro-extraction (SPME) methods for In Vitro-In Vivo extrapolation of environmental chemicals. Toxicology in Vitro2019;60:245-251 R835612 (Final) (10/10/19)
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Journal Article Luo Y, Ferguson K, Rusyn I, Chiu W. In Vitro Bioavailability of the Hydrocarbon Fractions of Dimethyl Sulfoxide Extracts of Petroleum Substances. Toxicological Sciences 2020;174(2):168-177. R835612 (Final) (06/18/20)
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Journal Article Rusyn I, Chiu W, Wright F. Model systems and organisms for addressing inter-and intra-species variability in risk assessment. REGULATORY TOXICOLOGY AND PHARMACOLOGY 2022;132(105197). R835612 (Final) (09/08/22)
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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Last updated April 28, 2023
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