Grantee Research Project Results
Publications submitted after final report Details for Grant Number R835550
Identification and Scientific Validation of AOPS Involving Genomic and Nongenomic Intracellular Thyroid Hormone Signaling in Neurodevelopment
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| Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year (Date Added to Report) | Document Sources |
|---|---|---|---|---|---|---|
| Journal Article | Bifenthrin causes transcriptomic alterations in mTOR and ryanodine receptor-dependent signaling and delayed hyperactivity in developing zebrafish (Danio rerio). | None | Frank DF, Miller GW, Harvey DJ, Brander SM, Geist J, Connon RE, Lein PJ | Frank DF, Miller GW, Harvey DJ, Brander SM, Geist J, Connon RE, Lein PJ. Bifenthrin causes transcriptomic alterations in mTOR and ryanodine receptor-dependent signaling and delayed hyperactivity in developing zebrafish (Danio rerio). Aquatic Toxicology 2018;200:50-61. |
R835550 (Final) (08/05/22) R835799 (2017) (09/05/18) |
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| Journal Article | Ontogeny of biochemical, morphological and functional parameters of synaptogenesis in primary cultures of rat hippocampal and cortical neurons. | MOLECULAR BRAIN | Harrill JA, Chen H, Streifel KM, Yang D, Mundy WR, Lein PJ | Harrill JA, Chen H, Streifel KM, Yang D, Mundy WR, Lein PJ. Ontogeny of biochemical, morphological and functional parameters of synaptogenesis in primary cultures of rat hippocampal and cortical neurons. Molecular Brain 2015;8:10 (15 pp.). |
R835550 (Final) (06/20/18) |
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| Journal Article | TBBPA Targets Converging Key Events of Human Oligodendrocyte Development Resulting in Two Novel AOPs | ALTEX | Klose J, TRigges J, Masjosthusmann S, Schmuck K, Bendt F, Hubenthal U, Petzsch P, Kohrer K, Koch K, Fritsche E | Klose J, TRigges J, Masjosthusmann S, Schmuck K, Bendt F, Hubenthal U, Petzsch P, Kohrer K, Koch K, Fritsche E. TBBPA Targets Converging Key Events of Human Oligodendrocyte Development Resulting in Two Novel AOPs. Altex 2021;38(2):215-234. |
R835550 (Final) (06/17/21) |
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| Journal Article | Transcriptomic profiling of mTOR and ryanodine receptor signaling molecules in developing zebrafish in the absence and presence of PCB 95. | None | Frank DF, Miller GW, Connon RE, Geist J, Lein PJ | Frank DF, Miller GW, Connon RE, Geist J, Lein PJ. Transcriptomic profiling of mTOR and ryanodine receptor signaling molecules in developing zebrafish in the absence and presence of PCB 95. PeerJ 2017;5:e4106. doi:10.7717/peerj.4106. |
R835550 (Final) (08/05/22) |
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| Journal Article | A multi-tiered, in vivo, quantitative assay suite for environmental disruptors of thyroid hormone signaling. | None | Mengeling BJ, Wei Y, Dobrawa LN, Streekstra M, Louisse J, Singh V, Singh L, Lein PJ, Wulff H, Murk AJ, Furlow JD | Mengeling BJ, Wei Y, Dobrawa LN, Streekstra M, Louisse J, Singh V, Singh L, Lein PJ, Wulff H, Murk AJ, Furlow JD. A multi-tiered, in vivo, quantitative assay suite for environmental disruptors of thyroid hormone signaling. Aquatic Toxicology 2017;190:1-10. |
R835550 (Final) (06/17/21) |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.