IRIS Toxicological Review of Trichloroacetic Acid (TCA) (External Review Draft)
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The draft Toxicological Review of trichloroacetic acid provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to trichloroacetic acid. Trichloroacetic acid is used as an antiseptic, skin peeling agent, and chemical intermediate to produce a variety of organic chemicals. Trichloroacetic acid is also used industrially as an etching and pickling agent for surface treatment of metals and as a solvent in the plastics industry. Trichloroacetic acid is formed from organic materials during water chlorination. This assessment contains the derivation of a chronic reference dose and cancer oral slope factor.
|Mar 1996||EPA posted the IRIS assessment for trichloroacetic acid on the IRIS database (cancer assessment only).|
|Sep 2009||EPA released an external review draft for public review and comment. A public listening session to discuss the report will be held on November 4, 2009.|
|Sep 2009||EPA hosted an interagency science discussion on the review of the draft IRIS Summary and Toxicological Review of Trichloroacetic Acid.|
|Nov 2009||EPA announces the details of an external peer review workshop to be held on December 10, 2009 in a November 10, 2009 Federal Register Notice.|
|Jan 2010||EPA releases the comments from the public comment period and external review workshop.|
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