IRIS Toxicological Review of Trichloroacetic Acid (TCA) (Interagency Science Consultation Draft)
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The draft Toxicological Review of Trichloroacetic Acid provides scientific support and rationale for the hazard identification and dose-response assessment pertaining to chronic exposure to trichloroacetic acid. Trichloroacetic acid is used as an antiseptic, skin peeling agent, and chemical intermediate to produce a variety of organic chemicals. Trichloroacetic acid is also used industrially as an etching and pickling agent for surface treatment of metals and as a solvent in the plastics industry. Trichloroacetic acid is formed from organic materials during water chlorination.
This assessment contains the derivation of a chronic reference dose and cancer oral slope factor.
|1996||EPA posted the IRIS assessment for trichloroacetic acid on the database (cancer assessment only).|
|2004||EPA started IRIS reassessment of trichloroacetic acid cancer assessment and assessment of noncancer endpoints.|
|Sep 2009||EPA released an External Reviewer Draft for public comment and review.|
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