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Welcome to the U.S. EPA ECOTOX, Version 4, Web site!

The ECOTOXicology knowledgebase (ECOTOX) is a source for locating single chemical toxicity data for aquatic life, terrestrial plants and wildlife. ECOTOX was created and is maintained by the U.S.EPA, Office of Research and Development (ORD) , and the National Health and Environmental Effects Research Laboratory's (NHEERL's) Mid-Continent Ecology Division (MED).

ECOTOX integrates three previously independent databases - AQUIRE, PHYTOTOX, and TERRETOX - into a unique system which includes toxicity data derived predominately from the peer-reviewed literature, for aquatic life, terrestrial plants, and terrestrial wildlife, respectively. 

You should review the limitations of ECOTOX data retrieval and system requirements prior to performing searches this site.

You should consult the original scientific paper to ensure an understanding of the context of the data retrieved from ECOTOX.

ECOTOX History

AQUIRE: In 1981, MED began developing the AQUIRE (AQUatic toxicity Information REtrieval) database with assistance from the Office of Toxic Substances and the Office of Water. AQUIRE was initially developed to store acute laboratory data, but underwent major changes in the early 1990s, encoding additional parameters to better present data from outdoor field and chronic exposures. AQUIRE was released to governmental users via a telephone dial in session in 1987. In April 1999, AQUIRE was made available on the World Wide Web to all interested parties; public and private.

PHYTOTOX:  The PHYTOTOX database was developed at the NHEERL, Western Ecology Division in Corvallis, OR (WED-Corvallis) in the early 1980s, but is currently maintained at MED. PHYTOTOX was originally developed with funding from the U.S. EPA Office of Pesticides through a cooperative agreement with the University of Oklahoma.  

TERRETOX:  The TERRETOX database was developed at WED-Corvallis in the early 1980s and is currently maintained at MED-Duluth.  Initial funding for TERRETOX came from the U.S. EPA's Office of Toxic Substances.

ECOTOX:  In 1995, MED received funding from the U.S. Department of Defense's Strategic Environmental Research and Development Program (SERDP) and the U.S. EPA's Office of Research and Development to develop a unified interface called ECOTOX to assist in searching and retrieving data from the AQUIRE, PHYTOTOX and TERRETOX databases. In March of 1996, ECOTOX was released to governmental users through a telnet access procedure.  In February, 2000 it was released as a web based interface system.

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