Office of Research and Development Publications

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Williams, A. AND J. Sobus. Applications of the US EPA CompTox Chemicals Dashboard to support mass spectrometry and breath research. Edition 2nd, Chapter 39, Breathborne Biomarkers and the Human Volatilome. Elsevier B.V., Amsterdam, Netherlands, , 649-661, (2020). https://doi.org/10.1016/B978-0-12-819967-1.00039-6

Knudsen, T. Chapter 24 - Can Computational Models Be Used to Assess the Developmental Toxicity of Environmental Exposures? Chapter 24, Teratology Primer, Third Edition. John Wiley & Sons Inc, Malden, MA, , 1-5, (2018).

Leung, M., N. Baker, AND T. Knudsen. Chapter 50 - Systems Toxicology and Predictive Modeling of Male Developmental Toxicity. Chapter 50, Reproductive and Developmental Toxicology. Elsevier Inc, Waltham, MA, , 975-985, (2017). https://doi.org/10.1016/B978-0-12-804239-7.00050-0

Knudsen, T. AND G. Daston. 5.22 - Systems Toxicology and Virtual Tissue Models. Chapter 5, Comprehensive Toxicology, 3rd Edition. Elsevier Online, New York, NY, 5:351-362, (2018). https://doi.org/10.1016/B978-0-12-801238-3.95684-8

Saili, K., T. Zurlinden, AND T. Knudsen. Modeling the Neurovascular Unit In Vitro and In Silico. Chapter 11, Handbook of Developmental Neurotoxicology’, 2nd edition. Academic Press Incorporated, Orlando, FL, , 127-142, (2018). https://doi.org/10.1016/B978-0-12-809405-1.00011-0

Fourches, D., A. Williams, G. Patlewicz, I. Shah, Chris Grulke, J. Wambaugh, A. Richard, AND A. Tropsha. Computational tools for ADMET profiling. Chapter 8, Computational Toxicology: Risk Assessment for Chemicals. John Wiley & Sons Inc, Malden, MA, , 211-244, (2018). https://doi.org/10.1002/9781119282594.ch8

Thomas, R. AND M. Waters. Transcriptomic Dose-Response Analysis for Mode of Action and Risk Assessment. Chapter 5, Michael D. Waters, Russell S. Thomas (ed.), Issues in Toxicology: Toxicogenomics in Predictive Carcinogenicity: Current Issues and Future Applications. Royal Society of Chemistry, Cambridge, Uk, (28):154-184, (2016).

Mansouri, K. AND R. Judson. In silico study of in vitro GPCR assays by QSAR modeling. Chapter 16, Emilio Benfenati (ed.), In Silico Methods for Predicting Drug Toxicity - vol. 1425 of Methods in Molecular Biology . Springer Science + Business Media, New York, NY, 1425:361-381, (2016).

HOUCK, K. A., A. M. RICHARD, R. S. JUDSON, M. T. MARTIN, D. REIF, AND I. A. SHAH. ToxCast: PREDICTING TOXICITY POTENTIAL THROUGH HIGH-THROUGHPUT BIOACTIVITY PROFILING. 1st Edition, , Chapter 1, Pablo Steinberg (ed.), High-Throughput Screening Methods in Toxicity Testing. John Wiley & Sons, Inc, Hoboken, NJ, , 3-31, (2013).

KNUDSEN, T. B., M. T. MARTIN, K. J. CHANDLER, N. KLEINSTREUER, R. JUDSON, AND N. SIPES. Predictive Models and Computational Toxicology. Chapter 26, Paul C.Barrow (ed.), Teratogenicity Testing; Methods and Protocols. Humana Press Incorporated, Totowa, NJ, 947:343-374, (2013).

DAVIS, J., R. TORNERO-VELEZ, AND R. W. SETZER. Computational Approaches for Developing Informative Prior Distributions for Bayesian Calibration of PBPK Models (Book Chapter). Chapter 18, James B. Knaak, Charles Timchalk, Rogelio Tornero Velez (ed.), Parameters for Pesticide QSAR and PBPK/PD Models for Human Risk Assessment. ACS Publications, Washington, DC, 1099:291-306, (2012).

GALLAGHER, K., F. M. GOODSAID, D. J. DIX, S. EULING, M. KRAMER, N. MCCARROLL, J. PRESTON, P. SAYRE, B. SEN, D. WOLF, AND W. H. BENSON. Toxicogenomics and the Regulatory Framework. Chapter 14, Darrell R. Boverhof and B. Bhaskar Gollapudi (ed.), Applications of Toxicogenomics in Safety Evaluation and Risk Assessment. John Wiley & Sons Incorporated, New York, NY, , 293-321, (2011).

KNUDSEN, T. B. ToxCast and Virtual Embryo: in vitro data and in silico models for predictive toxicology. Chapter 3.3, Troy Seidle and Horst Spielmann (ed.), AXLR8-3 Alternative Testing Strategies; Progress Report 2012. Springer-Verlag, Berlin, Germany, , 193-200, (2012).

KNUDSEN, T. B. The VIRTUAL EMBRYO. A Computational Framework for Developmental Toxicity. Chapter 3.3, Troy Seidle and Horst Spielmann (ed.), AXLR8-2 Alternative Testing Strategies Progress Report 2011. Springer-Verlag, Berlin, Germany, , 253-258, (2011).

BARRIER, M., K. J. CHANDLER, S. C. JEFFAY, M. R. HOOPES, T. B. KNUDSEN, AND E. S. HUNTER. Mouse Embryonic Stem Cell Adherent Cell Differentiation and Cytotoxicity (ACDC) Assay: Book Chapter. 2012 Edition, Chapter 11, Craig Harris; Jason M. Hansen (ed.), Developmental Toxicology; Methods and Protocols; Series: Methods in Molecular Biology, Springer Protocols. Humana Press Incorporated, Totowa, NJ, 889:181-196, (2012).

JUDSON, R. Differential Toxicity Characterization of Green Alternative Chemicals. Chapter 2, Paul T. Anastas, Robert S. Boethling, Adelina Voutchkova (ed.), Handbook of Green Chemistry: Set III; Green Processes - Designing Safer Chemicals. Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, 9:21-46, (2012).

KNAAK, J. B., C. C. DARY, X. Zhang, R. W. Gerlach, R. TORNERO-VELEZ, D. CHANG, M. GOLDSMITH, AND J. N. BLANCATO. Parameters for Pyrethroid Insecticide QSAR and PBPK/PD Models for Human Risk Assessment . Chapter INT, Springer, New York, NY, 219:1-114, (2012).

KLEINSTREUER, N. C. AND T. B. KNUDSEN. Predictive Modeling and Computational Toxicology. Third Edition, Chapter 23, Ronald D.Hood (ed.), Developmental and Reproductive Toxicology: A Practical Approach. Informa Healthcare Books, UK, London, Uk, , 578-591, (2011).

KNUDSEN, T. B. AND R. DEWOSKIN. Systems Modeling in Developmental Toxicity. 1st Edition, Chapter 37, Daniel A. Casciano; Saura C. Sahu (ed.), Handbook of Systems Toxicology. John Wiley and Sons, LTD, , Uk, 2:599-617, (2011).

SINGH, A. V., R. J. KAVLOCK, A. M. RICHARD, AND C. YANG. Computational Toxicology. Second Edition, Chapter 21, Knudsen, T., Daston,GP (ed.), Comprehensive Toxicology. Elsevier Ltd, Oxford, Uk, 12:307-337, (2010).

KNUDSEN, T. B. AND G. P. DASTON. Virtual Tissues and Developmental Systems Biology (book chapter). Second Edition, Chapter 23, Knudsen,T. and Daston,G. (ed.), Comprehensive Toxicology. Elsevier Ltd, Oxford, Uk, 12:347-358, (2010).

DASTON, G. P. AND T. B. KNUDSEN. Fundamental concepts, current regulatory design and interpretation . Second Edition, Chapter 12, Kudsen, T., Daston, GP (ed.), Comprehensive Toxicology. Elsevier Ltd, Oxford, Uk, 12:3-9, (2010).

KAVLOCK, R. J. Can Chemicals in the Environment That Affect Hormone Function Disrupt Development? Second Edition, Chapter 27, Barbara Hales; Anthony Scialli; Melissa S. Tassinari (ed.), Teratology Primer. John Wiley & Sons Incorporated, New York, NY, 1(2):71-72, (2010).

SINGH, A. V. AND T. B. KNUDSEN. How Can We Use Bioinformatics to Predict Which Agents Will Cause Birth Defects? Second Edition, Chapter 19, Barbara Hales; Anthony Scialli; Melissa S. Tassinari (ed.), Teratology Primer. John Wiley & Sons Incorporated, New York, NY, 1(2):51-53, (2010).

KNUDSEN, T. B. Can Computational Models Be Used to Assess the Developmental Toxicity of Environmental Exposures? Second Edition, Chapter 18, John Wiley & Sons Incorporated, New York, NY, 1(2):48-50, (2010).