Jump to main content or area navigation.

Contact Us

Environmental Assessment

IRIS Toxicological Review of 1,1,2,2-Tetrachloroethane (2010 Final Report)

Report Information

EPA is announcing the release of the final report, Toxicological Review of 1,1,2,2-Tetrachloroethane: in support of the Integrated Risk Information System (IRIS). The updated Summary for 1,1,2,2-Tetrachloroethane and accompanying Quickview have also been added to the IRIS Database.

Jump to Table of Contents document
Martin Gehlhaus
  • by phone at:   703-347-8579
  • by email at:  gehlhaus.martin@epa.gov

Background

The Toxicological Review of 1,1,2,2-tetrachloroethane provides scientific support and rationale for the hazard and dose-response assessment pertaining to subchronic and chronic exposure to 1,1,2,2-tetrachloroethane. 1,1,2,2 Tetrachloroethane (1,1,2,2TCE; CASRN 79-34-5) is a synthetic halogenated hydrocarbon that is a colorless, nonflammable liquid at room temperature. The major use for 1,1,2,2 tetrachloroethane was in the production of trichloroethylene, tetrachloroethylene, and 1,2-dichloroethylene. This assessment contains the derivation of both a subchronic and chronic reference dose and an oral cancer slope factor. EPA is also putting forth for external review the statement that the human carcinogenic potential of 1,1,2,2-tetrachloroethane is “likely to be carcinogenic to humans”.

History/Chronology

September 2010EPA released the final tox report and summary document and posted these to the IRIS database.

Citation

U.S. EPA. IRIS Toxicological Review of 1,1,2,2-Tetrachloroethane (2010 Final Report). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-09/001, 2010.

Downloads

Related Links

Jump to main content.