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25
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2025
U. S. federal perspective on critical research issues in nanoEHS
(JOURNAL) [Published : Aug 31, 2023]
(JOURNAL) [Published : Aug 31, 2023]
This article discusses critical issues and opportunities going forward in nanotechnology environmental, health, and safety (nanoEHS) research from the perspective of Federal Government agency participants in the U.S. National Nanotechnology Initiative (NNI) interagency Nanotechno...
Antibiotic Resistance in Plastisphere
(JOURNAL) [Published : Dec 27, 2024]
(JOURNAL) [Published : Dec 27, 2024]
Microbial life on plastic debris, called plastisphere, has invoked special attention on aquatic ecosystems as emerging habitats for antibiotic resistance genes (ARG) and antibiotic-resistant bacteria (ARB). Micro- or nano-plastics formed through transport and degradation of plast...
Air Pollutant Impacts on the Brain and Neuroendocrine System with Implications for Peripheral Organs: A Perspective
(JOURNAL) [Published : Feb 07, 2023]
(JOURNAL) [Published : Feb 07, 2023]
Air pollutants are increasingly linked to extrapulmonary multi-organ effects. Specifically, recent studies associate air pollutants with brain disorders including psychiatric conditions, neuroinflammation and chronic diseases. Current evidence of linkage between neuropsychiatric ...
Transport Behavior and Applications of Nanomaterials for Water Treatment and Groundwater Remediation
(PRESENTATION) [Presented : Nov 04, 2024]
(PRESENTATION) [Presented : Nov 04, 2024]
Transport of nanomaterials are not well understood. We evaluated: 1) the effect of material properties on the aggregation and sedimentation kinetics of titanium dioxide nTiO2, reduced graphene oxide (RGO) and its hybrids with Ag0 and Fe3O4; 2) impurity dissolution kinetics and su...
Bimetallic catalyst system for the degradation of PCBs in sediments
(JOURNAL) [Published : Oct 01, 2024]
(JOURNAL) [Published : Oct 01, 2024]
QAPP for research: G-LRPCD-0020755-QP-1-5
SDMP for research: SDMP.FY24.88.0
SciHub entry (ScID): D-rjf5
In this paper, we report the successful application of a patent-pending reduced bimetallic nanoparticle catalytic system developed for the remediation of polychlorinated...
Semantic Integration of US Federal Nanomaterials Data - Open Source Software FCSM Conference Session Invitation 10/22/2024
(PRESENTATION) [Presented : Oct 22, 2024]
(PRESENTATION) [Presented : Oct 22, 2024]
Dr. Chris Marcum, Senior Statistician and Senior Scientist from the Office of the Chief Statistician of the United States has organized a symposium entitled "Open Source Software in the Federal Statistical System" accepted by the Federal Committee on Statistical Methodo...
IRIS Toxicological Review of Perfluorodecanoic Acid (PFDA) and Related Salts (Public Comment and External Review Draft)
(IRIS ASSESSMENT) [Published : Apr 10, 2023]
(IRIS ASSESSMENT) [Published : Apr 10, 2023]
In April 2023, the IRIS Program released the draft IRIS Toxicological Review of Perfluorodecanoic Acid (PFDA) and Related Salts for public comment and external peer review. The IRIS assessment of PFDA will undergo an independent external scientific peer review managed by ERG, a c...
2024
Comparing the definitions of microplastics based on size range: Scientific and policy implications
(JOURNAL) [Published : Sep 07, 2024]
(JOURNAL) [Published : Sep 07, 2024]
The term ‘Microplastic’ was coined about 20 years ago by Thompson et al. (2004). Defining the term microplastics (MP) can stir strong sentiments in some microplastic research and management circles. Some venture that if these particles had not been called &l...
EPA's Air Methods for Measuring PFAS in Source Emissions
(PRESENTATION) [Presented : Jul 24, 2024]
(PRESENTATION) [Presented : Jul 24, 2024]
As the regulatory framework to address PFAS in the environment continues to develop, so do the analytical methods used to detect nano-level quantities from all media. This webinar will provide a detailed review of stationary source analytical methods for air emissions Other Test ...
Toxicological Review of Perfluorodecanoic Acid (PFDA) and Related Salts (Final Report, 2024)
(IRIS ASSESSMENT) [Published : Jul 16, 2024]
(IRIS ASSESSMENT) [Published : Jul 16, 2024]
EPA has finalized the IRIS Toxicological Review of Perfluorodecanoic Acid (PFDA) and Related Salts. This assessment addresses the potential cancer and noncancer human health effects from exposure to PFDA and related salts. EPA’s program and regional offices may use this assessmen...
Toxicological Review of Perfluorodecanoic Acid (PFDA) and Related Salts (Interagency Science Discussion Draft, 2024)
(IRIS ASSESSMENT) [Published : Apr 24, 2024]
(IRIS ASSESSMENT) [Published : Apr 24, 2024]
In July 2024, EPA finalized the IRIS Toxicological Review of Perfluorodecanoic Acid (PFDA) and Related Salts. The Toxicological Review was reviewed internally by EPA and by other federal agencies and White House Offices after public release in April 2023. Consistent with the May ...
NNI nanoinformatics conference 2023: Movement toward a common infrastructure for federal nanoEHS data computational toxicology: Short communication
(JOURNAL) [Published : Jun 01, 2024]
(JOURNAL) [Published : Jun 01, 2024]
The National Nanotechnology Initiative organized a Nanoinformatics Conference in the 2023 Biden-Harris Administration’s Year of Open Science, which included interested U.S. and EU stakeholders, and preceded the U.S.-EU COR meeting on November 15th, 2023 in Washington, D.C. Progre...
Mining, refining, and QSAR analysing the nanoinformatics in EPA NaKnowBase
(JOURNAL) [Published : Apr 17, 2024]
(JOURNAL) [Published : Apr 17, 2024]
Concerns about the safety of manufacturing and using engineered nanomaterials (ENMs) have been increasing as the technology continues to expand. Efforts have been underway to investigate the potentially harmful effects of ENMs without carrying out the challenging empirical studie...
Translating nanoEHS data using EPA NaKnowBase and the Resource Description Framework
(JOURNAL) [Published : Mar 08, 2024]
(JOURNAL) [Published : Mar 08, 2024]
Background: The U.S. Federal Government has supported the generation of extensive amounts of nanomaterials and related nano Environmental Health and Safety (nanoEHS) data, there is a need to make these data available to stakeholders. With recent efforts, a need for improved inter...
Interactive effects of changes in UV radiation and climate on terrestrial ecosystems, biogeochemical cycles, and feedbacks to the climate system
(JOURNAL) [Published : May 01, 2023]
(JOURNAL) [Published : May 01, 2023]
Terrestrial organisms and ecosystems are being exposed to new and rapidly changing combinations of solar UV radiation and other environmental factors because of ongoing changes in stratospheric ozone and climate. In this Quadrennial Assessment, we examine the interactive effects ...
The elemental fingerprint as a potential tool for tracking the fate of real-life model nanoplastics generated from plastic consumer products in environmental systems
(JOURNAL) [Published : Jan 01, 2024]
(JOURNAL) [Published : Jan 01, 2024]
Metals and metalloids are widely used in producing plastic materials as fillers and pigments, which can be used to track the environmental fate of real-life nanoplastics in environmental and biological systems. Therefore, this study investigated the metal and metalloids concentra...
Analytical Methods for Microplastic Detection in Drinking Water
(PRESENTATION) [Presented : Sep 14, 2023]
(PRESENTATION) [Presented : Sep 14, 2023]
Microplastic contamination raises concerns in drinking water quality due to difficulties in removing them during treatment and potential for contaminant leaching. EPA’s Office of Research and Development is interested in developing sampling and analytical methods for microp...
CeO2 nanoparticle dose and exposure modulate soybean development and plant-mediated responses in root-associated bacterial communities
(JOURNAL) [Published : May 03, 2024]
(JOURNAL) [Published : May 03, 2024]
Agricultural soils are increasingly undergoing inadvertent and purposeful exposures to engineered CeO2 nanoparticles (NPs), which can impact crops and root-associated microbial communities. However, interactions between NP concentration and exposure duration on plant-mediate...
Micro- and Nanoplastics in Marine Sediment: Detecting Particles and Assessing Impacts on Benthic Communities
(PRESENTATION) [Presented : Mar 28, 2024]
(PRESENTATION) [Presented : Mar 28, 2024]
Plastic particles are now found ubiquitously in the environment. As the abundance of plastic increases in marine systems, the magnitude of adverse biological and ecological effects of plastics of various size classes (macro-, micro-, nano-) need to be evaluated for potential risk...
Emerging contaminant research at the US EPA: PFAS and microplastics
(PRESENTATION) [Presented : Nov 17, 2022]
(PRESENTATION) [Presented : Nov 17, 2022]
Per- and polyfluoroalkyl substances (PFAS) are a group of man-made chemicals that have been in use since the 1940s in a wide array of consumer products. PFAS are persistent in the environment and bioaccumulate. Thermal treatment methods are currently applied to a variety of mater...
The environmental fate, transformation, and speciation of nano-copper oxide in a freshwater environment
(PAPER IN NON-EPA PROCEEDINGS) [Published : Jul 08, 2022]
(PAPER IN NON-EPA PROCEEDINGS) [Published : Jul 08, 2022]
The use and production of engineered nanomaterials have grown rapidly over the past few decades due to their unique properties and versatility. However, the full extent of nanomaterials’ impact on the environment is currently unknown. In this study, we use the W...
Effects of Copper Nanoparticles on mRNA and Small RNA Expression in Human Hepatocellular Carcinoma (HepG2) Cells
(JOURNAL) [Published : Oct 01, 2021]
(JOURNAL) [Published : Oct 01, 2021]
With the advancement of nanotechnology, nanoparticles are widely used in many different industrial processes and consumer products. Copper nanoparticles (Cu NPs) are among the most toxic nanomaterials. We investigated Cu NPs toxicity in Human Hepatocellular carcinoma (HepG2) cell...
Novel use of Nano Materials for degradation of PCB
(PRESENTATION) [Presented : Oct 14, 2022]
(PRESENTATION) [Presented : Oct 14, 2022]
Persistent organic pollutants (POPs) such as Polychlorinated biphenyls (PCBs) are notorious for their widespread prevalence in aquatic and sedimentary ecosystems, recalcitrance, and carcinogenicity. Dredging and land-filling are still commonly used for treating PCB contaminated m...
Micro- and Nanoplastics Plastic Pollution Research at the EPA
(PRESENTATION) [Presented : Nov 28, 2023]
(PRESENTATION) [Presented : Nov 28, 2023]
Plastic particles are found ubiquitously in the environment, and as plastic abundance increases in marine systems, the adverse biological and ecological effects of plastics of various size classes (macro-, micro-, nano-) needs to be evaluated for potential risks. Marine sediments...
Differential genomic effects of four nano-sized and one micro-sized CeO2 particles on HepG2 cells
(JOURNAL) [Published : Oct 01, 2023]
(JOURNAL) [Published : Oct 01, 2023]
The objective of this research was to perform a genomics study of five cerium oxide particles, 4 nano and one micrometer-sized particles which have been studied previously by our group with respect to cytotoxicity, biochemistry and metabolomics. Human liver carcinoma HepG2 c...