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25
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Methods and Datasets for 5-Day Oral Anatoxin-a Toxicity in Mice
(DATA/SOFTWARE) [Published : Jun 05, 2026]
(DATA/SOFTWARE) [Published : Jun 05, 2026]
Anatoxin-a (ATX) is a neurotoxic cyanotoxin found in freshwater globally. Multiple genera of cyanobacteria can produce anatoxins and include producers associated with planktonic blooms such as Aphanizomenon, Dolichospermum, and Planktothrix and those most associated with benthic ...
Methods and Dataset for Anatoxin-a and Metabolite Quantification in Mouse Gastric Contents After Oral Dosing with Anatoxin-a
(DATA/SOFTWARE) [Published : Jun 06, 2026]
(DATA/SOFTWARE) [Published : Jun 06, 2026]
Harmful algal blooms are occur frequently in fresh and marine waters. Anatoxin-a (ATX) is a neurotoxin produced by cyanobacteria mainly in freshwater. Human health guidelines are limited by a scarcity of toxicological data although it has caused illness in humans, and illness and...
Revisiting chlorophyll a thresholds for San Francisco Bay: insights from observations of phytoplankton molecular abundance
(JOURNAL) [Published : Feb 21, 2026]
(JOURNAL) [Published : Feb 21, 2026]
Harmful Algal Blooms (HABs) are a hazard for coastal environments worldwide; identifying screening thresholds of chlorophyll-a (chl-a) associated with increased risk of HABs is a management priority. Molecular surveillance of coastal phytoplankton and bivalve biotoxins ...
Harmful algal bloom impacts on foodweb structure in western Lake Erie
(JOURNAL) [Published : Jun 16, 2025]
(JOURNAL) [Published : Jun 16, 2025]
Human-driven environmental change has caused harmful algal blooms (HABs) to increase in aquatic ecosystems worldwide, yet our understanding of their impacts on food webs and the fisheries that they support remains incomplete. This information gap is especially conspicuous in Lake...
Cyanobacterial bloom occurrence and emergency department visits for asthma or wheeze, Wisconsin, 2017-2019
(JOURNAL) [Published : Jun 01, 2026]
(JOURNAL) [Published : Jun 01, 2026]
Background: Cyanobacterial harmful algal blooms (cyanoHABs) pose risks to human and animal health.
Methods: We investigated the relationship between cyanoHABs and asthma or wheeze-related emergency department (ED) visits near three Wisconsin cities (Green Bay, Madison, ...
Coastal Freshwater HABs
(PRESENTATION) [Presented : Apr 16, 2026]
(PRESENTATION) [Presented : Apr 16, 2026]
Cyanobacteria have recently been detected in coastal systems in the U.S., with cyanotoxins measured in shellfish in downstream estuaries at levels of
concern for human health. Goal 4 of EPA’s draft Harmful Algal Blooms (HABs) Strategy highlights EPA’s critical role in the Advanc...
How Satellites Help Detect and Forecast Cyanobacterial HABs
(PRESENTATION) [Presented : Apr 27, 2026]
(PRESENTATION) [Presented : Apr 27, 2026]
The Cyanobacteria Assessment Network (CyAN) is a multi-agency, satellite-enabled program that delivers daily, national-scale monitoring, summary metrics, and forecasting of cyanobacterial harmful algal blooms (cyanoHABs) for thousands of U.S. lakes using 300 m Sentinel-3 OLCI obs...
The development of DNA metabarcoding approaches for biomonitoring of streams and rivers of the United States
(PRESENTATION) [Presented : Apr 22, 2026]
(PRESENTATION) [Presented : Apr 22, 2026]
Interest in using DNA metabarcoding as part of monitoring and assessment programs continues to increase since 2020 when EPA first published a study on its use to quantify diatom responses to nutrients in streams at a watershed scale. Results from this initial work were subsequent...
How Satellites Help Detect and Forecast Cyanobacterial HABs
(PRESENTATION) [Presented : Apr 16, 2026]
(PRESENTATION) [Presented : Apr 16, 2026]
The Cyanobacteria Assessment Network (CyAN) is a multi-agency, satellite-enabled program that delivers daily, national-scale monitoring, summary metrics, and forecasting of cyanobacterial harmful algal blooms (cyanoHABs) for thousands of U.S. lakes using 300 m Sentinel-3 OLCI obs...
Work in Progress: Benthic HABs methods and survey of the Columbia River- Hanford and Richland Sections
(PRESENTATION) [Presented : Apr 16, 2026]
(PRESENTATION) [Presented : Apr 16, 2026]
In 2024/2025 spatially balanced probability surveys for benthic HABs were conducted in five different systems. Here we use the preliminary results of the survey of the Hanford and Richland Sections of the Columbia River near the Tri-Cities, WA to provide context and an update to ...
Benthic HABs methods and survey of the Columbia River- Hanford and Richland Sections
(PRESENTATION) [Presented : Apr 08, 2026]
(PRESENTATION) [Presented : Apr 08, 2026]
In 2024 a spatially balanced probability survey for benthic HABs was conducted in the Hanford and Richland Sections of the Columbia River near the Tri-Cities, WA. Thirty nine sites were visited late September and mid October. Surface water grab samples were taken at each. A trans...
Spring 2025 Puget Sound LCMS results for Aqueous and SPATT samples
(DATA/SOFTWARE) [Published : Mar 05, 2026]
(DATA/SOFTWARE) [Published : Mar 05, 2026]
Spring 2025 Puget Sound Liquid chromatography mass spectrometry (LCMS) algal toxin concentration results from aqueous and solid phase adsorption toxin tracking (SPATT) samples
2023-2025 Grand Lake St. Marys field parameters
(DATA/SOFTWARE) [Published : Apr 30, 2026]
(DATA/SOFTWARE) [Published : Apr 30, 2026]
This Dataset includes the spatial and temporal measurements of water quality probe parameters taken in the field within the canal and river system of St. Mary's, OH for the years 2023-2025.
HABS-BLOCKS© Reduced Harmful Algal Bloom Activity in an in-Lake Limno-Corral Mesocosm Case Study at Grand Lake St. Marys, Ohio (USA)
(JOURNAL) [Published : Mar 28, 2026]
(JOURNAL) [Published : Mar 28, 2026]
HABS-BLOCKS© infused with glucose have been shown to reduce cyanobacterial populations and microcystin (MC) concentrations in laboratory mesocosm studies. An in situ limno-corral (LC) mesocosm study of HABS-BLOCKS© was conducted for two weeks during the 2025 algal bloom...
Stable isotopes reveal an imprint of harmful algal blooms on Lake Erie
(JOURNAL) [Published : Jun 16, 2025]
(JOURNAL) [Published : Jun 16, 2025]
In Lake Erie, harmful algal blooms have become a recurrent problem during the summer-through-fall growing season. We investigated if the annual disturbance of harmful algal blooms in Lake Erie relates to distinct differences in carbon and nitrogen stable isotope composition (&del...
Prioritizing Alaska Public Water Systems Potentially Impacted by Harmful Algal Blooms
(PRESENTATION) [Presented : Feb 18, 2026]
(PRESENTATION) [Presented : Feb 18, 2026]
Compared to the contiguous United States (CONUS), little is currently known about the potential vulnerability of public water systems (PWS) in the State of Alaska to freshwater harmful algal blooms (HABs). A Regional-Office of Research and Development (ORD) Applied Research (ROAR...
Evaluation of a field method for qPCR analysis of toxigenic cyanobacteria
(JOURNAL) [Published : Apr 01, 2026]
(JOURNAL) [Published : Apr 01, 2026]
Quantitative Polymerase Chain Reaction (qPCR) is a well-established method for molecular detection and quantification of microorganisms. Molecular detection of toxigenic cyanobacteria using qPCR has also been employed as a useful tool for predicting cyanotoxin production and form...
Algal Blooms in Lakes Increase After Wildfire Smoke Events in the Contiguous United States
(JOURNAL) [Published : Mar 06, 2026]
(JOURNAL) [Published : Mar 06, 2026]
Area burned by wildfire has increased in the contiguous United States and in many places globally in recent years, impacting communities and ecosystems nearby and even far downwind of fires. We examined the potential effects of smoke on surface chlorophyll-a concentrations in lak...
The application of satellite technology for monitoring cyanobacterial harmful algal blooms in U.S. waters.
(PRESENTATION) [Presented : Mar 04, 2026]
(PRESENTATION) [Presented : Mar 04, 2026]
Cyanobacterial harmful algal blooms are widespread, dynamic, and consequential. Traditional field-based monitoring alone cannot provide the spatial and temporal coverage along, and this work examines how integrating satellite observations with in situ sampling and models enables ...
National forecasting of cyanobacterial harmful algal bloom events: a three-year model evaluation
(JOURNAL) [Published : Apr 01, 2026]
(JOURNAL) [Published : Apr 01, 2026]
Publicly available cyanobacterial harmful algal blooms (cyanoHAB) forecasts are now available at www.epa.gov/habs/hab-forecasts, offering water quality and public health managers a tool for anticipating cyanoHAB conditions in the largest United States lakes and reservoirs. T...
Update on Ohio River HABs Research and Monitoring
(PRESENTATION) [Presented : Feb 10, 2026]
(PRESENTATION) [Presented : Feb 10, 2026]
An update to the Ohio River Valley Water Sanitation Commission's Technical Committee on Ohio River HABs research and monitoring that occurred over 2025 will be provided. Progress for the year includes refinement of the 14 day ahead HABs occurrence forecast, revision of scripts us...
Gene Expression of Mouse Liver and Brain after 5-day Oral Exposure of Anatoxin-a
(DATA/SOFTWARE) [Published : Feb 17, 2026]
(DATA/SOFTWARE) [Published : Feb 17, 2026]
This subproduct is a gene count dataset generated by gene expression of mouse liver and brain tissue after exposure to 5 days of the freshwater cyanotoxin anatoxin-a. Male and female CD-1 mice were dosed with either vehicle (water), 2, 4, or 6 mg/kg (+)-anatoxin-a extracted and p...
Ecology of Lake Erie: Causes, consequences and management of eutrophication: A synthesis
(JOURNAL) [Published : Jun 16, 2025]
(JOURNAL) [Published : Jun 16, 2025]
Lake Erie has been re-experiencing excessive nutrient loading (i.e., eutrophication) during recent decades, the causes and consequences of which remain incomplete (Scavia et al., 2014; Sinclair et al., 2023; Watson et al., 2016). Our general understanding is that increased runoff...
Recommendations for temporal aggregation of water quality data from multi-platform satellite constellations
(JOURNAL) [Published : Jan 01, 2026]
(JOURNAL) [Published : Jan 01, 2026]
Satellite constellations often launch platforms over several years, increasing observational frequency and capturing additional, potentially more extreme, events. Consequently, reported changes in satellite-derived data may inadvertently capture variations in observational freque...
Identification of Anatoxin-a and Related Metabolites in Exposed Mice Samples with a High-Resolution Mass Spectrometry Discovery Workflow
(JOURNAL) [Published : Aug 20, 2025]
(JOURNAL) [Published : Aug 20, 2025]
Harmful cyanobacterial blooms (HCBs) are a public health concern and require ongoing surveillance to monitor the negative water quality effects and cyanotoxins associated with these blooms. (+)-Anatoxin-a (ATX) is a potent neurotoxin produced by select cyanobacteria during HCB fo...