Science Inventory

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Acute and long-term exposure to per- and polyfluoroalkyl substances (PFAS) is of rising concern due to their persistent detection and abundance in the environment coupled with their potential for bioaccumulation. The replacement of legacy PFAS with ether-linked carboxylic acid (P...

Presentation to Aquaculture America 2024, Zebrafish Husbandry Workshop and Summit

The analysis of contaminants of emerging concern (CECs) has been an ongoing priority due to their potential for adverse effects on environmental and human health. Wastewater is a source for many CECs, and surface waters that receive wastewater discharge often serve as source wate...

The purpose of this letter is to correct previously reported blood serum concentrations for PFO5DoA in people in Wilmington, North Carolina (NC), in 2017-2018 [1]. Perfluoro-3,5,7,9,11-pentaoxadodecanoic acid (known as PFO5DoA; Chemical Abstracts Service Number [CASN] 39492-91-6,...

These data were recently presented at SOT 2024 as a poster, and this sub-product will present the same data and analyses in a presentation at a local society meeting of endocrine disrupting chemicals NC (EDC-NC). Sprague-Dawley rat dams were exposed via oral gavage from GD18-22 t...

Presentation 01/08/2023 -International Conference on the Remediation and Management of Contaminated Sediments.  Topic: Analytical methods for PFAS in environmental media. Types of analytical and standard methods. Drinking Water Sample Methods Method 537 Method 533 Non-Drink...

Seven-day sublethal toxicity tests were performed with the freshwater invertebrates&nbsp;Ceriodaphnia dubia,&nbsp;Hyalella azteca, and&nbsp;Chironomus dilutus&nbsp;to determine the effects of per- or polyfluorinated alkyl substances (PFAS) of varying chain length within four clas...

Over the last decade, applications of non-target analysis (NTA) for environmental monitoring have detected dozens of novel PFAS in the Cape Fear Region (CFR) of North Carolina including GenX (HFPO-DA), Nafion byproduct 2 (BP2), and perfluoroether carboxylic acids with four (PFO4D...

Industrial producers and users of per- and polyfluorinated alkyl substances (PFAS) have been a major source of chemical contamination due to historical releases of legacy PFAS. Following the general phase-out of legacy PFAS such as PFOA/PFOS, industrial usage has shifted to alter...

This is a requested presentation for the Association of Clean Water Administrators (ACWA) that discusses how ORD is the research arm of the EPA and provides the scientific foundation for EPA to execute its mandate to protect human health and the environment. An overview of the 6 ...

&nbsp; Samples from 450 homes with shallow private wells throughout the state of Wisconsin (USA) were collected and analyzed for 44 individual per- and polyfluoroalkyl substances (PFAS), general water quality parameters, and indicators of human waste as well as agricultural inf...

Multiple per- and polyfluoroalkyl ether acids have recently been detected in drinking water and/or human serum, but there is a paucity of data on potential toxicity despite known exposure.&nbsp; Perfluoro-2-methoxyacetic acid (PFMOAA) is a short chain ether carboxylate (3 carbons...

Per- and polyfluoroalkyl substances (PFAS) are persistent organic pollutants with emerging environmental and regulatory concerns. &nbsp;We estimated PFAS groundwater concentrations for every ZIP code tabulated area (ZCTA) in 40 California counties where 25 percent or more of the ...

This work investigated the suitability of three non-hazardous food dyes as PFAS simulants during wastewater treatment with powdered activated carbon (PAC). Data from batch experiments with PAC revealed equilibrium constants (Log Kd) and pseudo first-order adsorption rate constant...

BACKGROUND. While major pathways of human PFAS exposure are thought to be drinking water and diet, other pathways and sources have also been shown to contribute to a person’s cumulative exposure. However, the degree of contribution of these other sources to PFAS body burdens is s...

Abstract reduced to fit RAPID character limits - full abstract attached Background and Purpose Recent human and ecological biomonitoring studies in the US and China have identified novel perfluoroalkyl carboxylic acids with ether linkages between each fluorinated carbon in a homo...

Due to the pervasive detection of multiple PFAS in human and environmental matrices, many health-based agencies are employing or pursuing cumulative assessment and regulatory approaches.&nbsp; However, the literature is lacking mammalian in vivo studies that test additivity by co...

Background and Purpose: Per- and polyfluoro-alkyl substances (PFAS) are a large and diverse class of organic chemicals in which all (per-) or some (poly-) carbon&ndash;hydrogen bonds have been replaced with carbon&ndash;fluorine bonds. PFAS are commonly found in human tissues. S...

&nbsp;The shift from PFOS and PFOA production in the past 20 years towards shorter chain and replacement PFAS has led to the environmental release of complex mixtures of emerging PFAS with unknown bioaccumulation potential and toxicology. Prioritizing research on merging PFAS in ...

Background:&nbsp;A fluorochemical facility near Fayetteville, North Carolina, emitted per- and polyfluoroalkyl ether acids (PFEAs), a subgroup of per- and polyfluoroalkyl substances (PFAS), to air. Objective:&nbsp;Analyze PFAS in private wells near the facility and in blood from ...

In March 2024, the IRIS Program released the draft IRIS Toxicological Review of Perfluorononanoic Acid (PFNA) and Related Salts for public comment and external peer review. The IRIS assessment of PFNA will undergo an independent external scientific peer review managed by ERG, a c...

Home plumbing can be contaminated with PFAS from aqueous film forming foams (AFFF) through accidental backflow resulting from firefighting related activities, including back-siphoning during routine maintenance of equipment.  This exact incident did occur in Wyoming, OH in 2018, ...

To present EPA/ORD's Technical Assistance project on treating emerging contaminants

Many aqueous film forming foam (AFFF) delivery systems in aircraft hangars and firefighting vehicles may require thorough cleaning to avoid ongoing environmental impacts from residual per- and polyfluoroalkyl substances (PFAS) within those systems. Though replacement AFFF formula...

To present EPA/ORD's technical assistance project on emerging contaminants.