Science Inventory

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The large number of diverse chemicals in production or in the environment has motivated medium to high throughput in vitro or small animal approaches to efficiently profile chemical-biological interactions and to utilize this information to assess risks of chemical exposures on h...

Evaluating the thousands of chemicals that are directly added to or come in contact with food poses a great challenge due to the time, cost, and sheer volume of data necessary to thoroughly conduct comprehensive toxicological testing. This study compiled a list of food-use chemic...

This book chapter discusses various catalysts for environmental remediation. Detailed information on catalysis using ferrate and ferrite oxidation, TiO2 photocatalysis, and new catalysts (i.e., graphene, perovskites and graphitic carbon nitride) is provided for the degradation of...

Research has shown that current-use pesticides can enter urban and agricultural watersheds and adversely affect aquatic organisms. A potential cause may be higher concentrations of the more toxic pesticide enantiomer present in the pesticide mixture. The presence of pesticide ena...

Eighteen pesticides being reviewed as a part of the EPA Substitute Chemical Program were tested for mutagenic activity by the following in vitro procedures: (1) Reverse mutation in Salmonella typhimurium strains TA1535, TA1537, TA1538, TA98, and TA100 and in Escherichia coli WP2 ...

THE US EPA'S N-METHYL CARBAMATE CUMULATIVE RISK ASSESSMENT (NMCRA) ASSESSES THE EFFECT ON ACETYLCHOLINE ESTERASE (AChE) ACTIVITY OF EXPOSURE TO 10 N-METHLY CARBAMATE (NMC)PESTICIDES THROUGH DIETARY, DRINKING WATER, AND RESIDENTIAL EXPOSURES. THESE DATA THUS INFORM, BUT DO NOT COM...

A wide range of perfluorinated organic compounds (PFCs) has been used in a variety of industrial processes and consumer products. The most commonly studied PFCs include perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA), but there are many more compounds in this c...

Template for symposia abstracts submission; requirements for symposium organisers.(European Spelling)

This study investigated the presence and human hazards associated with pesticides and other anthropogenic chemicals identified in kale grown in urban and rural environments. Pesticides and related compounds (i.e., surfactants and metabolites) in kale samples were evaluated using ...

This research was conducted in cooperation with EPA Region 4 in Athens, GA to develop a method to analyze selected pyrethroid pesticides using Reverse Phase-High Pressure Liquid Chromatography (HPLC). This HPLC method will aid researchers in separating and identifying these pyre...

PowerPoint presentation summarizing method development research involving the persistent perfluorinated organic compounds. Review of data indicating widespread distribution of these materials and the potential for toxicity.

PowerPoint presentation summarizing method development research involving the persistent perfluorinated organic compounds. Review of data indicating widespread distribution of these materials and the potential for toxicity.

PowerPoint presentation summarizing method development research involving the persistent perfluorinated organic compounds. Review of data indicating widespread distribution of these materials and the potential for toxicity.

PowerPoint presentation summarizing method development research involving the persistent perfluorinated organic compounds. Review of data indicating widespread distribution of these materials and the potential for toxicity.

Overview of significant research activities that have been initiated by the USEPA to increase understanding of children’s vulnerabilities and to better characterize children’s exposures to chemical stressors.

Carbonyl sulfide (COS) is a chemical intermediate in the production of pesticides and herbicides, is a metabolite of carbon disulfide, is produced by the combustion of organic material, and is found occurring in nature. COS was included in a Toxic Substances Control Act request f...

The purpose of the Mississippi River map series is to provide reference for ecological vulnerability throughout the entire Mississippi River Basin, which is a forthcoming product. This map series product consists of seven 32 inch x 40 inch posters, with a nominal scale of 1 inch ...

We have applied a method for quantifying relative levels of messenger RNA (mRNA) transcription to assess chemically-induced gene expression in fathead minnows (Pimephales promelas). Synthetic oligonucleotides designed for the fathead minnow vitellogenin gene transcription (Vg) p...

Oral presentation at the meeting of the ORSANCO Research Committee, December 2, 2004.

There is no abstract available for this product. If further information is requested, please refer to the bibliographic citation and contact the person listed under Contact field.

This report includes proceedings from the 2013 NIEHS/EPA Children's Centers Annual Meeting, held in Washington D.C. in October, 2013. Summaries of presentations, speaker biosketches, poster abstracts, and a meeting participant list are all included.

The report includes proceedings from the 2015 NIEHS/EPA Children's Centers Annual Meeting. The proceedings include presentation summaries, speaker biosketches, poster abstracts, and a list of meeting participants.

The U.S. Environmental Protection Agency (EPA) is faced with the challenge of efficiently evaluating chemical safety often with access to only sparse toxicity data. The increasing number of chemicals found in commerce and the environment, together with the time and resource requi...

Species differences in the intrinsic clearance (CL<SUB>int</SUB>) and the enzymes involved in the metabolism of pyrethroid pesticides were examined in rat and human hepatic microsomes. The pyrethroids bifenthrin, S-bioallethrin, bioresmethrin, β-cyfluthrin, cypermethrin, cis-per...

Recent studies suggest that environmental substances that mimic endogenous estrogens (eg. estradiol) may disrupt the endocrine system. While high-level exposures to estrogenic substances are believed to contribute to such adverse effects as cancer, developmental disorders, and fe...