Science Inventory

<< Previous

Next >>

Background and Purpose Computational toxicology and exposure modeling efforts require access to a broad variety of data. The US EPA Center for Computational Toxicology and Exposure (CCTE) has developed a suite of tools, including the CompTox Chemicals Dashboard and ChemExpo onlin...

This subproduct was a training webinar on the Chemicals and Products Database and the Chemical Exposure Knowledgebase (ChemExpo) presented to the California Department of Toxic Substances Control as part of a series on CCTE Tools.

Currently, jurisdictions and individuals are challenged to consider the full range of information required to manage and use chemicals in a way that protects and promotes public health. Research to apply and demonstrate approaches that leverage disparate information by combining ...

This is an invited presentation for the EPA/ORD-NIEHS/NICETAM Workshop: Advancing Quantitative Analysis in Human Health Assessments through Probabilistic Method. It describes the different exposure-based new approach methods (NAMs) that have been proposed by ORD's ExpoCast group ...

Exposure to fine particulate matter (PM2.5) from wildfire smoke is an important and growing risk to public health. Reducing personal exposure from public health actions can minimize adverse health effects associated with PM2.5 from wildfire smoke. To motivate individuals to modif...

In the United States (US), workers represent a &ldquo;highly exposed and susceptible subpopulation&rdquo; that must be considered by the US Environmental Protection Agency (EPA) when evaluating new or existing chemicals under the amended Toxic Substances Control Act (TSCA). Howev...

Monitoring chemical occurrence in various environmental media yields gold-standard information for characterizing the mechanisms by which human and ecological receptors are exposed to exogenous chemicals.&nbsp; Monitoring data support the parameterization of quantitative exposure...

This is an oral presentation for the Accelerating the Pace of Chemical Risk Assessment (APCRA) annual meeting in 2024. No abstract was required.

Chemical risk assessment relies on knowledge of hazard, the dose&ndash;response relationship, and exposure to characterize potential risks to public health and the environment. A chemical with minimal toxicity might pose a risk if exposures are extensive, repeated, and/or occurri...

Background Lead (Pb) in house dust contributes significantly to blood lead levels (BLLs) in children which may result in dire health consequences. Assessment of house dust Pb in the United States, relationships with Pb in soil and paint, and residential factors influencing Pb con...

The webinar does not have the abstract.&nbsp;

An oil burn experiment was conducted at the University of Alaska Fairbanks&rsquo; Poker Flat Research Range on a subset of a 1 ha artificial pond during August 2-3, 2022. The downwind PM 2.5 concentrations were measured with unmanned aircraft systems (UAS) flown by the U.S. Geolo...

The webinar series and workshop titled &ldquo;Trust Your Gut: Establishing Confidence in Gastrointestinal Models &ndash; An Overview of the State of the Science and Contexts of Use&rdquo; was co-organized by NICEATM, NIEHS, FDA, EPA, CPSC, DoD, and the Johns Hopkins Center for Al...

&nbsp; Residential lead (Pb) exposure is of critical concern to families globally as Pb promotes severe neurological effects in children, especially those less than 5 years old, and no blood lead level is deemed safe by the US Center for Disease Control. House dust and soils ar...

ChemExpo is an interactive web application for exploring chemical data, curated from public documents, relevant to exposure assessment. ChemExpo currently surfaces data collected by EPA about how chemicals are used in commerce and how they occur in consumer and industrial product...

This is a guide for users who wish to explore data available on U.S. EPA&rsquo;s Chemical Exposure Knowledgebase (ChemExpo). It is appropriate for both experienced users and those who may be new to the application. The goal is to simplify a user&rsquo;s experience navigating the ...

This release of SHEDS-HT (v0.1.10) updates the model to include input data developed from EPA's Chemicals and Products Database (CPDat) Version 3. Other changes include: &nbsp; - Updated function documentation- Updated functionality with regard to SHEDS-HH home location set-up- A...

N/A

N/A

Evidence suggests that clothing can influence human exposure to semi-volatile organic compounds (SVOCs) through transdermal uptake and inhalation. Accordingly, a computational modeling framework (ABICAM) was expanded and applied to assess the dynamics of human exposure to gas-pha...

Background: The number of chemicals present in the environment exceeds the capacity of government bodies to characterize risk. Therefore, data-informed and reproducible processes are needed for identifying chemicals for further assessment. The Minnesota Department of Health (MDH)...

Background and Purpose An ongoing and primary research endeavor of the US EPA includes the evaluation of chemical risk to environmental and human health as well as modes of traversal from commercial sources and industrial processes to environmental and ecological media (including...

Abstract for invited SOT 2024 session &quot;Practical applications of machine learning for gaining mechanistic insights in toxicology&quot; Monitoring of chemical occurrence in various environmental media is gold-standard information for characterizing the mechanisms by which hum...

Under the Toxic Substances Control Act (TSCA), the US Environmental Protection Agency (US EPA) is required to determine whether a chemical substance poses an unreasonable risk before the chemical is manufactured in or imported into the United States. This presentation provides an...

Under the Toxic Substances Control Act (TSCA), the US Environmental Protection Agency (US EPA) is required to determine whether a chemical substance poses an unreasonable risk before the chemical is manufactured in or imported into the United States. This presentation will provid...