Science Inventory

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Invited Question and Answer article for Nature Cardiovascular Research on Particulate Matter.Recent air-quality alerts in major cities due to the wildfires in Canada, Hawaii and Greece have put fine particulate matter (PM) pollution and consequent health issues into the spotlight...

Wetland restoration and construction are important land management options for retaining nitrogen and phosphorus and thereby improving water quality at local scales (i.e., at nearby streams). However, limited information exists regarding the cumulative influence of wetlands outsi...

Agricultural best management practices/conservation practices (ag BMPs/ACPs) have been widely implemented for nonpoint source pollution control. However, through a Region 10 R2P2 project, we have identified two critical knowledge gaps that limit broader adoption of ACPs in the Pa...

Over the last 10 years the EPA has been conducting research to better quantify the magnitude of greenhouse gas emissions from US reservoirs.   In 2021 reservoirs were included in the Inventory of US Greenhouse Gas Emissions and Sinks for the first time and currently estimate...

To continue estimating hedonic property models, possibly expanding environmental justice analyses, and undertaking other analyses that use property characteristics, EPA is interested in acquiring national property transaction data as a replacement for Zillow’s ZTRAX data. Z...

Thoughtful science communication is essential for the success of collaborative, transdisciplinary environmental research. We present an innovative evaluation of a four-year pilot project that took a highly engaged and collaborative approach to managing excess nutrients in the Cap...

For decades, researchers have sought to document injustices, highlight activism, and identify pathways in moving toward environmental justice (EJ). EJ research regarding water has been predominantly focused on drinking water. This project sought to identify and analyze the breadt...

New approach methodologies (NAMs) are being evaluated for their utility to inform developmental neurotoxicity (DNT) hazard instead of using animals. This work compares predictive models for DNT using DNT NAMs data. The dataset comprised 200 chemicals screened in 17 DNT assays wit...

This is a public presentation on the potential effects of nutrients in smoke on downwind cyanobacteria blooms. Wildfire activity is increasing in the continental U.S. and can be linked to climate change effects, including rising temperatures and more frequent drought conditions. ...

The relationship between environmental chemical exposure and a spectrum of neurological diseases is well-established. However, unraveling the underlying mechanism between human exposure and toxic outcomes presents significant challenges. Evaluation of neurotoxicity potential usin...

The meeting aims to 1) discuss progress towards updating the Initial Recommendations to an OECD guidance, 2) discuss the regulatory implementation of the current DNT-IVB and strategy to include/exclude additional assays, and 3) discuss complementary aspects of the guidance that a...

Neurite outgrowth is an important precursor to synapse formation and assays for neurite outgrowth are part of an in vitro battery (IVB) of assays for developmental neurotoxicity screening (DNT). This battery of assays evaluates chemical effects on key neurodevelopmental processes...

Background and Purpose: Current in vitro toxicology methods typically rely on exposure of cells to compounds that were added to the culture media. For neurotoxicity, in vitro exposure of rat cortical neural networks plated on multi-well microelectrode array plates (MEAs) have bee...

EPA has conducted prior decontamination research for traditional CWAs, but there is a scientific data gap for decontamination technologies capable of remediating sensitive equipment contaminated with a Fourth Generation Agent (FGA). The purpose of this project was to evaluate the...

Background: In vitro new approach methods (NAMs) have been developed for evaluating developmental neurotoxicity (DNT) potential. One such DNT NAM, the Network Formation Assay (NFA), uses a twelve-day exposure model to measure neuronal network activity changes in primary rat corti...

A probability-based sampling design can be used to create statistically defensible sampling plans. However, these plans may have sampling collection and/or processing demands that exceed allotted resources. Targeted sampling designs, also referred to as judgmental sampling, use p...

Secondary organic aerosol (SOA) from acid-driven reactive uptake of isoprene epoxydiols (IEPOX) contributes up to 40% of organic aerosol (OA) mass in fine particulate matter. Previous work showed substantial conversions of particulate inorganic sulfates to surface-active organosu...

Atmospheric nitrate is a key atmosphere component with implications for air quality, nutrient deposition, and climate.  However, accurately representing atmospheric nitrate concentrations within atmospheric chemistry models is a persistent challenge.  A contributing fac...

This is an invited outreach presentation to provide an introduction to environmental justice. It presents no new data or ongoing research from ORD.

This presentation seeks to provide basic information about PFAS chemistry, occurrence, and accumulation/potential impacts in biota to a group of non-scientists. This presentation includes no EPA data. 

Arsenic discharge and mobilization from the pollution source depend on the minerals that host arsenic, the matrix of local water, the redox condition, and the water flow. A disposable enzyme sensor has been developed for As(III) determination in site assessment. To evaluate the s...

The US EPA has developed a set of annual North American anthropogenic and fire emissions data for criteria air pollutants across 18 broad source catagories for 2002 through 2017.  The sixteen new annual emissions inventories were developed using consistent input data and met...

Over the past decade, a concerted effort has been made to develop in vitro and alternative assays that detect compounds with the potential to cause developmental neurotoxicity. As a result, a battery of assays has been developed that is believed to be useful for decision-making r...

While SWMM has arguably played a pivotal role in pollution control in collection systems since its introduction, traditional applications using the model have been relatively static. They typically involve calibrating and validating SWMM models with data collected and curated for...

Protein processing operations include animal slaughtering, meat and poultry product production, and/or rendering of byproducts. These facilities utilize large volumes of water for hair/hide/feather removal, carcass washing, chilling, trimming and cutting, cooking, and cleaning/sa...