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ANALYSES OF FISH TISSUE BY VACUUM DISTILLATION/GAS CHROMATOGRAPHY/MASS SPECTROMETRY
Citation:
Hiatt, M. ANALYSES OF FISH TISSUE BY VACUUM DISTILLATION/GAS CHROMATOGRAPHY/MASS SPECTROMETRY. Analytical Chemistry 69(6):1127-1134, (1997).
Description:
The analyses of fish tissue using VD/GC/MS with surrogate-based matrix corrections is described. Techniques for equilibrating surrogate and analyte spikes with a tissue matrix are presented, and equilibrated spiked samples are used to document method performance. The removal of analytes from the tissue corresponds to Koa and Kwa (octanol-air and water-air partition coefficients, respectively). For a given vacuum distillation, the impact of Koa and Kwa on analyte recovery can be determined by interpreting the recoveries of surrogate compounds and their Koa and Kwa. The use of these surrogates to monitor and correct for both water-air and octanol-air partitioning provides average recoveries of 86% for volatile gases, 97% for volatiles, 90% for neutral semivolatiles, 124% for basic semivolatiles, and 87% for the water-soluble volatiles. The method detection limits are sub-parts-per-billion for most analytes studied. A technique to experimentally determine the octanol-air partition relative volatility is described and the values for 113 compounds are presented.