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DOSE RESPONSE MODELING FOR 2, 3, 7, 8-TETRACHLORODIBENZO-P-DIOXIN
Citation:
DeVito, M J., A. C. Kim, N. J. Walker, F. Parham, AND C. J. Portier. DOSE RESPONSE MODELING FOR 2, 3, 7, 8-TETRACHLORODIBENZO-P-DIOXIN. 2nd, Chapter 7, A. Schecter and T. Gasiewicz (ed.), Dioxins and Health. John Wiley & Sons Incorporated, New York, NY, , 247-298, (2003).
Description:
As science continues to appreciate the prevalence and power of dioxins, so it learns more about the harmful effects and effective preventive measures regarding these chemicals. Updating the acclaimed First Edition, Dioxins and Health, Second Edition covers the latest major scientific findings on the most potent, well known, and long-lasting of the persistent organic pollutants (POPS).
The Second Edition of the book reflects significant advances in dioxin research made in human epidemiology as well as in animal studies. Dioxins and structural analogues have been proven to cause immune alterations, nervous system effects, and cancer in humans, leading to its designation as a carcinogen by the World Health Organization. Endocrine alterations, caused by dioxins, have been shown to produce diabetes mellitus in adults and thyroid and sex hormone changes in newborns. The Second Edition reflects these new findings in a wide-ranging survey of these ubiquitous toxins.