Science Inventory

The Childrens Total Exposure to Persistent Pesticides and Other Persistent Organic Pollutants (CTEPP) Study


The CTEPP study is the largest aggregate exposure study of preschool children (ages 2 to 5 years) conducted in the United States. The CTEPP study was designed in part to fill in critical data gaps on young children’s exposures to pesticides in response to the Food Quality Protection Act (FQPA) of 1996.


The Children's Total Exposure to Persistent Pesticides and Other Persistent Pollutant (CTEPP) study was one of the largest aggregate exposure studies of young children in the United States. The CTEPP study examined the exposures of about 260 preschool children and their primary adult caregivers to pollutants commonly found in their everyday environments. The major objectives of this three-year study were to quantify children's aggregate exposures, to apportion the exposure pathways, to identify the important exposure media, and to identify the important hypotheses for future testing. Participants were recruited from randomly selected day care centers and homes in six North Carolina (NC) and six Ohio (OH) counties. Monitoring was performed over 48-hr periods at the children's homes and/or day care centers. Multimedia samples that were collected included duplicate diet, drinking water, indoor air, outdoor air, urine, floor dust, play area soil, transferable residues, and surface wipes (hand, food preparation, and hard floor). The samples were extracted and analyzed by gas chromatography/mass spectrometry for over 50 pollutants including pesticides, phthalate esters, phenols, polychlorinated biphenyls, and polycyclic aromatic hydrocarbons. In addition, 20% of the preschool children were videotaped for about 2 hours at homes in OH to supplement the activity diaries and observations. All of the measurement data and associated information was incorporated into the CTEPP database. The data were statistically analyzed to quantify the concentrations of these pollutants in multimedia and to estimate the exposures through the inhalation, ingestion, and dermal routes of the preschool children through environmental sampling, time?activity diaries, food diaries and questionnaires. This database is one of the largest resources for characterizing young children's exposures to pollutants in their everyday environments.



Record Details:

Record Type: PROJECT
Start Date: 10/01/2011
Completion Date: 10/01/2011
OMB Category: Other
Record ID: 76506