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TREATMENT OF CONTAMINATED SOIL WITH PHOSPHORUS AND MANGANESE OXIDE REDUCES LEAD ADSORPTION BY SPRAGUE-DAWLEY RATS
Citation:
Hettiarachchi**, G. M., G. M. Pierzynski, F. W. Oehme, O. Sonmez, AND J A. Ryan*. TREATMENT OF CONTAMINATED SOIL WITH PHOSPHORUS AND MANGANESE OXIDE REDUCES LEAD ADSORPTION BY SPRAGUE-DAWLEY RATS. JOURNAL OF ENVIRONMENTAL QUALITY. ASA, CSSA, SSSA, Madison, WI, 32(4):1335-1345, (2003).
Description:
A study was conducted to determine the extent of adsorption of Pb into young rats that were fed Pb contaminated soil treated with two different sources of P and P plus Mn oxide. Attempts were also made to compare an in vitro, physiologically based extraction procedure test (PBET) data with animal data and to provide support for the validity of the in vitro test to assess potential bioavailable Pb from a treated Pb-contaminated soil. A metal contaminated soil (total Pb concentration of 2290 mg/kg) collected from Joplin, MO was used. A total of 152 male Sprague-Dawley rats, six weeks of age at the start of dosing were fed 19 different test diets for 21 consecutive days. The Pb concentrations in four different body compartments; blood, bone, liver and kidney were examined after termination. For all four tissues, Pb concentations for the Pb acetate groups were significantly higher than the Pb concentrations for all the soil Pb groups. In general, either Triple superphosphate (TSP) or phosphate rock (PR) treatments resulted significant reductions in tissue Pb concentration compared to the untreated soil fed group. Blood and kidney Pb concentrations for the PR plus Mn oxide group were significantly lower than that of the PR group at the low and high dose levels, indicating that PR with Mn oxide may be more effective in reducing Pb bioavilability than PR alone. Further, correlation between the in vitro test and animal data (in vivo) based on both bone and liver tissues showed that the in vitro test is about 90% successful at predicting Pb bioavailability.