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EOSINOPHIL INFLUX TO THE NASAL AIRWAY FOLLOWING LOCAL, LOW-LEVEL LPS CHALLENGE IN HUMANS
Citation:
Peden, D. P., P Murphy, L. NewlinClapp, B. A. Boehlecke, P A. Bromberg, W. Reed, K. Murphy, AND M. Hazcha. EOSINOPHIL INFLUX TO THE NASAL AIRWAY FOLLOWING LOCAL, LOW-LEVEL LPS CHALLENGE IN HUMANS. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 104:388-394, (1999).
Description:
Background: Recent obervations show that atopic asthmatic subjects have increased sensitivity to respirable endotoxin (or LPS) compared with normal persons. In vitro studies demonstrate that LPS enchances eosinophil survival. These obervations suggest that the effects of inhaled LPS in asthmatic subjects may include increases in the number of airway eosinophils.
Record Details:
Record Type:DOCUMENT( JOURNAL/ PEER REVIEWED JOURNAL)
Product Published Date:08/01/1999
Record Last Revised:12/22/2005
Record ID:
65816