EPA Science Inventory

PAIRED CITY CRYPTOSPORIDIUM SEROSURVEY

Citation:

Frost, F. J., T. Muller, G. F. Craun, R L. Calderon, AND P. A. Roefer. PAIRED CITY CRYPTOSPORIDIUM SEROSURVEY. EPIDEMIOLOGY AND INFECTION. Cambridge University Press, , Uk, 126:301-307, (2001).

Description:

In 1996, serological responses to two Cryptosporidium antigens were determined for 200 Las Vegas (LV), Nevada, and 200 Albuquerque, New Mexico, blood donors to evaluate associations between endemic infections, water exposures, and other risk factors. LV uses chlorinated filtered drinking water from Lake Mead while Albuquerque uses chlorinated ground water. The intensity of serological response to both markers was higher for older donors (p<0.05), donors who washed food with bottled water (p<0.05) and donors from LV (p<0.05). A decreased serological response was not associated with bottled water consumption, nor was an increased response associated with self-reported cryptosporidiosis-like illness or residence in LV at the time of a cryptosporidiosis outbreak two years earlier. Although these findings suggest the serological response may be associated with type of tap water and certain foods, additional research is needed to clarify the importance of both food and drinking water for endemic Cryptosporidium infection.

Record Details:

Record Type: DOCUMENT (JOURNAL/PEER REVIEWED JOURNAL)
Start Date: 08/01/2001
Completion Date: 08/01/2001
Record Last Revised: 12/22/2005
Record Created: 09/26/2003
Record Released: 09/26/2003
Record ID: 65021

Organization:

U.S. ENVIRONMENTAL PROTECTION AGENCY

OFFICE OF RESEARCH AND DEVELOPMENT

NATIONAL HEALTH AND ENVIRONMENTAL EFFECTS RESEARCH LAB

HUMAN STUDIES DIVISION

EPIDEMIOLOGY AND BIOMARKERS BRANCH