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OVERVIEW OF EPA'S HUMAN EXPOSURE AND SOURCE-TO-DOSE MODELING PROGRAM: HEADSUP
Citation:
Ozkaynak, A H., G F. Evans, D A. Pahl, AND J A. Graham. OVERVIEW OF EPA'S HUMAN EXPOSURE AND SOURCE-TO-DOSE MODELING PROGRAM: HEADSUP. Presented at ISEA 2000 Exposure Analysis in the 21st Century: Integrating Science, Policy and Quality of Life, Monterey Peninsula, CA, October 24-27, 2000.
Impact/Purpose:
The primary objective of this research project is to develop a scientifically-robust, complete multimedia, multi-pathway human exposure source-to-dose modeling system with modules and computational tools that can estimate exposures and doses to the general population, as well as to identifiable susceptible subpopulations, and can predict and diagnose the complex relationships which exist between source and exposure and dose -- and to ensure that this scientifically sound model, with its associated tools and the various modules included within, meets the needs of Program Offices and the scientific community for conducting risk assessments.
Description:
EPA's human exposure and source-to-dose modeling program is designed to provide a scientifically sound approach to understanding how people are actually exposed to pollutants and the magnitude of predicted exposures and dose. The objective of this research project is to develop a comprehensive human exposure source-to-dose (HES2D) model that can estimate multimedia, multi pathway human exposures and doses to both the general population and to identifiable susceptible subpopulations. The HES2D modeling framework is designed to predict and diagnose the complex relationships between emissions from different sources of pollutants and resulting human exposures and dose. This research program also serves to integrate and incorporate human exposure measurements, models, and methods from all aspects of EPA's research programs into a comprehensive, scientifically sound approach for evaluating human exposures. To assist the Agency in this endeavor, EPA has entered into multi-year assistance agreements with two research consortia who possess extensive experience in human exposure modeling and risk assessment. The Human Exposure and Dose Simulation University Partnership (HEASDUP) program involves five-year agreements with the Lawrence Berkeley National Laboratory (LBNL) and with the Environmental and Occupational Health Sciences Institute (EOSHI). To date, extensive collaboration among the three research groups (EPA, LBNL and EOSHI) has produced various modeling algorithms, inputs and simulation modules that can be used to estimate human exposures to particulate matter (PM) and pesticides. This symposium includes various presentations on key research components of the HEASDUP program, including applications of an integrated computer modeling platform (MENTOR) and the Stochastic Human Exposure and Dose Simulation (SHEDS) model for PM.
This abstract has been reviewed in accordance with the U.S. Environmental Protection Agency's peer and administrative review policies and approved for presentation and publication. Mention of trade names or commercial products does not constitute endorsement or recommendation for use.