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DATA REQUIREMENTS FOR ASSESSING CHILDREN'S EXPOSURE TO PESTICIDES
Citation:
CohenHubal, E A. AND L S. Sheldon. DATA REQUIREMENTS FOR ASSESSING CHILDREN'S EXPOSURE TO PESTICIDES. Presented at ACS National Meeting, New Orleans, LA, August 23, 1999.
Impact/Purpose:
1. To identify those pesticides, pathways, and activities that represent the highest potential exposures to children;
2. To determine the factors that influence pesticide exposures to children;
3. To develop methods for measuring multimedia exposures to children, including methods that account for important activities that take place in home, school, and day care settings;
4. To generate data on multimedia pesticide concentrations, pesticide biomarkers, and exposure factors that can be used as inputs to aggregate exposure models for children.
Description:
Several multimedia, multipathway exposure monitoring studies are currently being planned within EPA/NERL. The overall objectives of these studies are (1) to develop the data and models that can be used to estimate exposure and dose for young children to pesticides and (2) to identify and quantify important exposure factors for young children. To meet these objectives, data will be collected on pesticide concentrations in environmental media and on children's activity patterns. Data collection will focus on those microenvironments where children spend most of their time. These data will then be used as multipathway model inputs to estimate exposures. Concentration of urinary biomarkers will also be measured. These data will be combined with PBPK models to develop a second estimate of exposure. Comparisons between the two estimates will be used to evaluate and refine the various models. Given these objectives, a preliminary modeling approach was developed and used to identify data needs and to guide field sample collection. This approach ensures that samples and questionnaire information collected in these studies will provide the necessary data for assessing children's exposures to pesticides.
The U.S. Environmental Protection Agency through its Office of Research and Development funded and managed the research described here. It has been subjected to Agency review and approved for publication. Mention of trade names or commercial products does not constitute an endorsement or recommendation for use.