You are here:
BIOSENSORS
Citation:
Sharma, A. AND K. Rogers. BIOSENSORS. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-95/318.
Description:
It has recently been proposed under the International Union of Pure and Applied Chemistry (IUPAC) Commission that biosensors be regarded as a subgroup of chemical sensors in which a biologically based mechanism is used for detection of the analyte. hemical sensors are defined under this proposal as miniaturized transducers that selectively and reversibly respond to chemical compounds or ions, yielding an electrical signal which depends on an analyte concentration. lthough this definition excludes devices which employ irreversible binding (i.e., test strips, dipsticks and enzyme linked immunosorbent assay (ELISA) based formats), these systems are often discussed in the context of biosensor capabilities and future directions. otential advantages offered by biosensor technology include minimal sample preparation, high speed of analysis and the potential for in situ and flow stream analysis for process control. reas covered in the article include (1) user needs, (2) features, (3) molecular recognition, (4) signal transduction and, (5) biosensor applications.