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INVESTIGATION OF THE PERSISTENCE AND REPLICATION OF NUCLEAR POLYHEDROSIS VIRUSES IN VERTEBRATE AND INSECT CELL CULTURES BY THE USE OF HYBRIDIZATION TECHNIQUES
Citation:
Meinke, W., D. Goldstein, C. Alvidrez, J. Spizizen, AND C. William. INVESTIGATION OF THE PERSISTENCE AND REPLICATION OF NUCLEAR POLYHEDROSIS VIRUSES IN VERTEBRATE AND INSECT CELL CULTURES BY THE USE OF HYBRIDIZATION TECHNIQUES. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/1-80/026 (NTIS PB80202427), 1980.
Description:
The Health Effects Research Laboratory, Research Triangle Park, conducts a coordinaged environmental health research program in toxicology, epidemiology, and clinical studies using human volunteer subjects. These studies address problems in air pollution, non-ionizing radiation, environmental carcinogenesis, and the toxicology of pesticides as well as other chemical pollutants. The Laboratory develops and revises air quality criteria documents on pollutants for which national ambient air quality standards exist or are proposed, provides the data for registration of new pesticides or proposed suspension of those already in use, conducts research on hazardous and toxic materials, and is preparing the health basis for non-ionizing radiation standards. The majority of the registered pesticides are chemical agents. A few, however, are biological in nature because the active ingredients are microbial. Of these micro-organisms, viruses are perhaps the most unique in structure, biology, and the intimacy of their parasitic relationship with their hosts. This report considers whether potential biohazards to human health and other biological components of the environment exist when insect viruses are used as pesticides.