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INTRODUCTION AND STUDY DESIGN
Citation:
Sandhu, S., F. Serres, H. Gopalan, W. Grant, J. Veleminsky, AND G. Becking. INTRODUCTION AND STUDY DESIGN. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-94/525 (NTIS PB95148870), 1994.
Description:
Under the sponsorship of the UNEP/ILO/IPCS, 17 laboratories from diverse regions of the world participated in evaluating the utility of four plant bioassays for detecting genetic hazards of environmental chemicals. he bioassays included in this collaborative study were Arabidopsis embryo and chlorophyll assay and Tradescantia stamen hair assay, Tradescantia micronucleus assay, and Vicia faba root tip assay. four to six laboratories participated in the conductio of each of the bioassays. ll laboratories participating in a particular bioassay were supplied with uniform plant material as well as a standardized protocol. ive direct acting water soluble test chemicals- i.e.. maleic hydrazide, methyl nitrosourea, ethyl methanesulfonate, sodium azide. and azidoglycerol were selected for this study. he study was designed to be completed in three phases. thyl methanesulfonate was used as a positive control and has already been reported earlier (Sandhu et a]., 1991)...' The data from the remaining four chemicals used for the evaluation of four plant test. systems in first phase of the collaborative study are reported this volume.