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HISTOLOGICAL AND HISTOPATHOLOGICAL EVALUATION OF THE TESTIS
Citation:
Russel, L., R. Ettlin, A. Hikim, AND E. Clegg. HISTOLOGICAL AND HISTOPATHOLOGICAL EVALUATION OF THE TESTIS. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/8-91/012.
Description:
This book, the first to describe how the testis is evaluated in research and toxicology testing settings, is a resource for individuals who wish to perform a systematic evaluation of the testis. he book contains 728 illustrations and drawings. The book begins with a description of normal testis structure. t provides staging schemes for the three species (rat, mouse and dog) most commonly used in research and toxicology testing situations. Staging of spermatogenesis is designed to be self-taught. hapter on tissue preparation is written for the investigator to examine the options of tissue preparation available and to make a selection that suits a particular purpose. erfusion fixation of the testis is described in detail. istopathology of the testis is amply illustrated. nformation about the kinds of responses expected after variations in protocols is especially helpful to individuals planning experiments or testing protocols. oth qualitative and quantitative evaluation of the testis are stressed. Common morphological patterns of response are illustrated. hapter on the relationship of risk assessment to testis histology and histopathology is included to allow individuals to make an informed judgment about the best procedures to follow and how they should be viewed when making a risk assessment.