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Enriched housing alters cardiovascular function in male and female ApoE -/- mice and responsiveness to eucalyptus wildfire smoke
Citation:
Toler, S., M. Fiamingo, K. Lee, W. Oshiro, Todd Krantz, P. Evansky, D. Davies, Ian Gilmour, A. Farraj, AND M. Hazari. Enriched housing alters cardiovascular function in male and female ApoE -/- mice and responsiveness to eucalyptus wildfire smoke. Society of Toxicology, San Diego, California, March 27 - 31, 2022.
Impact/Purpose:
This study examined the impact of living conditions on the cardiovascular function of male and female atherosclerosis-prone mice and subsequent responses to eucalyptus wildfire smoke. The goal of this work was to determine if non-environmental stressors increase risk and the degree of resiliency conferred by housing enrichment.
Description:
This study showed that housing enrichment blunts the development of atherosclerosis effects in male and female mice and subsequent deleterious responses to wildfire smoke.