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Linking NRSA to the National Antimicrobial Resistance Monitoring System (NARMS): A Pilot Environmental Effort
Citation:
Garland, J., A. Franklin, M. Bagley, S. Keely, N. Brinkman, M. Jahne, AND L. Boczek. Linking NRSA to the National Antimicrobial Resistance Monitoring System (NARMS): A Pilot Environmental Effort. NRSA Steering Committee Meeting (Reoccuring), Virtual, Virtual, October 20, 2021.
Impact/Purpose:
Present an overview of the proposed use of NRSA samoples for the interagency NARMS effort to the NRSA steering committee.
Description:
The overall purpose of the Pilot Study is to develop a national-scale, quantitative assessment of AMR within surface water. The four main objectives as developed from initial meetings of the National Antimicrobial Resistance Monitoring System Environmental Working Group (NARMS EWG) are (I) standardized measure (and library of samples) to monitor trends as part of NARMS, (II) provide input to models of AMR risks for various end uses of water (recreational, drinking, agricultural, water reuse), (III) help quantify drivers of occurrence and selective pressures for potential amplification, and (IV) identify critical control points and assess current and new mitigation strategies. Scope of Work. 1) Phase 1: Method development to standardize methods for the analysis of antimicrobial resistant bacterial isolates (E. coli, Enterococcus spp., and Salmonella), antibiotic resistance genes and field collection of surface water samples. 2) Phase 2: Focused study to analyze antimicrobial resistance in the surface waters of a watershed. 3) Phase 3: Probabilistic study to analyze antimicrobial resistance in the surface waters nationwide. Phase 4: Additional focused watershed studies and nation-wide monitoring of antimicrobial resistance in the surface waters.