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Application of Cost Effectiveness and Value of Information Analyses in Evaluating the Utility of Toxicity-Testing Methodologies (APCRA)
Citation:
Price, P. AND R. Thomas. Application of Cost Effectiveness and Value of Information Analyses in Evaluating the Utility of Toxicity-Testing Methodologies (APCRA). 6th Annual Meeting of Accelerating the Pace of Chemical Risk Assessment (APCRA), N/A, North Carolina, October 14 - 15, 2021. https://doi.org/10.23645/epacomptox.16863604
Impact/Purpose:
This talk will present the results of an ongoing project to develop decision frameworks that objectively and transparently define prefered toxicity-testing methodologies. This guidance will support testing programs for the large numbers of untested chemicals in commercial use.
Description:
This presentation will cover work performed over the last two years by a team of ORD staff on a project to evaluate toxicity testing methodologies. The project developed two approaches for evaluating testing methodologies one based on Cost Effectiveness Analysis and the second on Value of Information. The approaches were used to evaluate the relative importance of cost, duration, and uncertainty in the toxicity tests.
URLs/Downloads:
DOI: Application of Cost Effectiveness and Value of Information Analyses in Evaluating the Utility of Toxicity-Testing Methodologies (APCRA)
APCRA 10-15-2.PDF (PDF, NA pp, 853.922 KB, about PDF)