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INACTIVATION OF HEPATITIS A VIRUS AND MS2 BY OZONE AND OZONE-HYDROGEN PEROXIDE IN BUFFERED WATER
Citation:
Hall, R. AND M. Sobsey. INACTIVATION OF HEPATITIS A VIRUS AND MS2 BY OZONE AND OZONE-HYDROGEN PEROXIDE IN BUFFERED WATER. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-94/572.
Description:
The comparative inactivation of highly purified hepatitis A virus (HAV) and MS2 by 1 mg H202/L, 2.0 and 0.4 mg 03/L, and 2.0 mg 03/L plus 0.6, 1.0, or 1.6 mg H202/L, at 3-10 degrees C, in 0.01 M phosphate buffer (pH 6-10) was determined. Both HAV and MS2 were completely inactivated 3.9-6 log10) within 5 seconds in ozone solutions. ydrogen peroxide did not inactivate MS2, but did inactivate 95% of the HAV. oth HAV and MS2 were completely (3.3-5.5 log) inactivated within 5 seconds in the oxidant mixtures at pH 6-8, but MS2 survival exceeded that of HAV at pH 10. S2 was found to be a good model for predicting HAV inactivation by ozone and mixtures of ozone and hydrogen peroxide when both viruses are purified in the same manner.