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Direct Aqueous Injection of the Fluoroacetate Anion in Potable Water for Analysis by Liquid Chromatography/Tandem Mass Spectrometry
Citation:
Willison, S. AND E. Parry. Direct Aqueous Injection of the Fluoroacetate Anion in Potable Water for Analysis by Liquid Chromatography/Tandem Mass Spectrometry. U.S. Environmental Protection Agency, Washington, DC, EPA/600/R-18/056, 2018.
Impact/Purpose:
Sodium fluoroacetate is a highly lethal pesticide, which is registered for use to control livestock. It does not have a known antidote and is stable in potable water. If a water contamination incident with this pesticide were to occur, a fast, robust analytical method would be needed for emergency response and remediation to ensure safe drinking water. To address this need, an analytical method for fluoroacetate salts was established for drinking water, which provides laboratories with the capability to analyze samples during an environmental response. The developed direct aqueous injection method eliminates the need for cumbersome sample preparation prior to analysis. Detection limit capabilities are 0.4 μg/L. This report, describes in detail, the direct inject method and optimized column chemistries for sensitive and accurate detection at very low levels in potable water sources. State, local and EPA Regional laboratories will now be able to use this robust and efficient method for a sodium fluoroacetate incident to detect, and recover from, an environmental contamination incident.
Description:
Sodium fluoroacetate is a highly lethal pesticide, which is registered for use to control livestock. It does not have a known antidote and is stable in potable water. If a water contamination incident with this pesticide were to occur, a fast, robust analytical method would be needed for emergency response and remediation to ensure safe drinking water. To address this need, an analytical method for fluoroacetate salts was established for drinking water, which provides laboratories with the capability to analyze samples during an environmental response. The developed direct aqueous injection method eliminates the need for cumbersome sample preparation prior to analysis. Detection limit capabilities are 0.4 μg/L. This report, describes in detail, the direct inject method and optimized column chemistries for sensitive and accurate detection at very low levels in potable water sources. State, local and EPA Regional laboratories will now be able to use this robust and efficient method for a sodium fluoroacetate incident to detect, and recover from, an environmental contamination incident.