Citation:

U.S. EPA. IRIS Toxicological Review of Ethyl Tertiary Butyl Ether (ETBE) (Interagency Science Discussion Draft, 2020). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-20/106, 2020.

Impact/Purpose:

EPA is undertaking an new health assessment for ethyl tertiary butyl ether (ETBE) for the Integrated Risk Information System (IRIS). The outcome of this project will be a Toxicological Review and IRIS Summary of ETBE that will be entered on the IRIS database. IRIS is an EPA database containing Agency scientific positions on potential adverse human health effects that may result from chronic (or lifetime) exposure to chemicals in the environment. IRIS contains chemical-specific summaries of qualitative and quantitative health information in support of two steps of the risk assessment process, i.e., hazard identification and dose-response evaluation. IRIS assessments are used nationally and internationally in combination with specific situational exposure assessment information to evaluate potential public health risks associated with environmental contaminants. The IRIS database is relied on for the development of risk assessments, site-specific environmental decisions, and rule making.

Description:

In August 2021, EPA finalized the IRIS assessment of ethyl tertiary butyl ether (ETBE). The Toxicological Review was reviewed internally by EPA and by other federal agencies and White House Offices after public release in June 2017. Consistent with the May 2009 IRIS assessment development process, all written comments on IRIS assessments submitted by other federal agencies and White House Offices are made publicly available. Accordingly, interagency comments and the interagency science discussion materials provided to other agencies, including interagency review drafts of the IRIS Toxicological Review of Ethyl Tertiary Butyl Ether are posted on this site.

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