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Draft Genome Sequences of Antibiotic-Resistant Escherichia coli Isolates from U.S. Wastewater Treatment Plants
Citation:
Gomez-Alvarez, V. AND J. Hoelle-Schwalbach. Draft Genome Sequences of Antibiotic-Resistant Escherichia coli Isolates from U.S. Wastewater Treatment Plants. Microbiology Resource Announcements. American Society for Microbiology, Washington, DC, 8(23):e00351-19, (2019). https://doi.org/10.1128/MRA.00351-19
Impact/Purpose:
Escherichia coli, a member of the family Enterobacteriaceae, is the predominant enterobacterial gut resident in humans and other mammals and is commonly used as an indicator of fecal pollution in source, drinking, and recreational waters. The occurrence of carbapenem-resistant Escherichia coli (CREC) in wastewater is a potential concern because this matrix may serve as a reservoir for gene exchange and thereby increase the risk of antibiotic-resistant (AR) bacteria (including carbapenem-resistant) being disseminated into the environment and thence back to humans. The purpose of this research is to characterize the resulting isolates for the presence of carbapenemase and ESBL genes and identify sequence types that have been associated with extraintestinal infections in humans.
Description:
The spread of antibiotic resistance is a major public health concern. We report the draft genome sequences of three Escherichia coli isolates from primary effluent collected from geographically dispersed US wastewater treatment plants (WWTPs). Genomic analysis confirms the presence of genes encoding resistance to a broad spectrum of antibiotics.
URLs/Downloads:
DOI: Draft Genome Sequences of Antibiotic-Resistant Escherichia coli Isolates from U.S. Wastewater Treatment Plants
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