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An AOP-based Ontology for Neural Tube Closure Caused by Disturbance in Retinoic Acid Signaling
Citation:
Staal, Y., N. Baker, L. Burgoon, G. Daston, T. Knudsen, AND A. Piersma. An AOP-based Ontology for Neural Tube Closure Caused by Disturbance in Retinoic Acid Signaling. Presented at European Society of Toxicology (Eurotox), Brussels, N/A, BELGIUM, September 02 - 05, 2018. https://doi.org/10.23645/epacomptox.7140866
Impact/Purpose:
Poster Presented to European Society of Toxicology (Eurotox) meeting Sep 2018
Description:
Retinoid signaling plays an important role in embryo- fetal development and its disruption is teratogenic. The biology of the RA pathway, leading to defects in neural tube closure was the basis for the construction of an ontology for developmental toxicity.
URLs/Downloads:
DOI: An AOP-based Ontology for Neural Tube Closure Caused by Disturbance in Retinoic Acid Signaling
010753_WP AN AOP-BASED ONTOLOGY FOR NEURAL TUBE CLOSURE_V1 YS_M.PDF (PDF, NA pp, 788.61 KB, about PDF)
Record Details:
Record Type:DOCUMENT( PRESENTATION/ POSTER)
Product Published Date:09/05/2018
Record Last Revised:10/23/2018
OMB Category:Other
Record ID:
342534