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Exposure-Based Context for Toxicology
Citation:
Wambaugh, J. AND B. Wetmore. Exposure-Based Context for Toxicology. IN: SOT Communique, Society of Toxicology, RESTON, VA, (1):1-3, (2017).
Impact/Purpose:
This is a submission to the Society of Toxicology (SOT) newsletter (The SOT Communique) designed to identify interest in founding an Exposure Specialty Section for the SOT. Depending on the feedback to this article, SOT may allow 50 SOT members to found a new specialty section that can solicit and endorse presentations for the SOT annual meeting and coordinate exposure-related activities among SOT members.
Description:
Over the course of our careers we have recognized the value and need for the incorporation of varied disciplines to explore the adoption of new tools and thought processes to address the challenges facing us as 21st century toxicologists. We have mutually benefited and see great value in facilitating similar interactions and collaborations amongst other researchers. We see the establishment of an Exposure Specialty Section as providing a key venue to facilitate such interactions and to allow dissemination of further relevant advances in this multifaceted research area. We intend to provide a forum across the field, with interactions among those working in exposure modeling (e.g., stochastic/probabilistic/Bayesian/far-field/near-field modeling, consumer product characterization, behaviors); advances in analytic tools (biomonitoring - suspect and non-targeted analyses; metabolomics); exposomics (EWAS); pharmacokinetic and population modeling (PBPK modeling; population variability); and integration with high throughput testing and other toxicity assessments (in vitro-in vivo extrapolation; high-throughput toxicokinetics; reverse dosimetry; aggregate exposure pathway).
