Science Inventory

Computational Embryology: Agent-Based Modeling and Simulation of External Genital Development

Citation:

Knudsen, T. Computational Embryology: Agent-Based Modeling and Simulation of External Genital Development. Presented at NIH-NIDDK/American Urological Association Workshop, Linthicum, MD, May 31 - June 01, 2018. https://doi.org/10.23645/epacomptox.6953021

Impact/Purpose:

Presentation given at NIH-National Institute of Diabetes and Digestive and Kidney Diseases/American Urological Association Workshop May 2018

Description:

Presentation of the US EPA's Virtual Tissue Model project using agent-based models (ABMs). ABMs can execute simulations that self-organize cells into high levels of biological structure and function (emergent phenotypes), and simulate perturbations in the system-dose or stage response, critical pathways, or non-chemical stressors. They can also make a probabilistic rendering of where, when and how a developmental defect might occur (mechanistic interpretation).

Record Details:

Record Type: DOCUMENT ( PRESENTATION/ SLIDE)
Product Published Date: 06/01/2018
Record Last Revised: 08/24/2018
OMB Category: Other
Record ID: 341915